{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:30:48Z","timestamp":1787758248882,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"\n The Rationale:<\/jats:title>\n Glanzmann thrombasthenia is a rare platelet disorder affecting 0.0001% of the population. Dentists may often be unaware of this condition, and manipulation of soft tissue can lead to grave consequences, which may even result in fatality.<\/jats:p>\n <\/jats:sec>\n \n Patient Concerns:<\/jats:title>\n In this case report, a 4-year-old patient with Glanzmann thrombasthenia reported to the department with a chief complaint of a discoloured tooth.<\/jats:p>\n <\/jats:sec>\n \n Clinical Findings:<\/jats:title>\n On examination, 51 was nonvital, and pulpectomy was the treatment planned. The non-vital anterior tooth was treated with a pulpectomy procedure. There was uncontrolled bleeding during the procedure.<\/jats:p>\n <\/jats:sec>\n \n Treatment:<\/jats:title>\n A topical solution of BotroClot was used to arrest the bleeding, and obturation was completed following that. The post-operative period was uneventful.<\/jats:p>\n <\/jats:sec>\n \n Take-away Lessons:<\/jats:title>\n Case report explored the use of a topical hemostatic agent to arrest bleeding from the canal. This case report warrants eliciting a thorough medical history before any dental procedure.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijdr.ijdr_1191_21","type":"journal-article","created":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T07:01:35Z","timestamp":1665644495000},"page":"219-222","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Glanzmann Thrombasthenia"],"prefix":"10.4103","volume":"33","author":[{"given":"Lalitha S.","family":"Jairam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil Babu","family":"Kotha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-23-20240828","first-page":"443","article-title":"Glanzmann's Thrombasthenia report of case and review of the literature","volume":"3","author":"Sebastiano","year":"2010","journal-title":"Int J Clin Exp Pathol"},{"key":"R2-23-20240828","doi-asserted-by":"crossref","first-page":"580","DOI":"10.5005\/jp-journals-10005-1973","article-title":"Glanzmann Thrombasthenia: Use of the soft splint with tranexamic acid paste to reduce spontaneous oral bleeding","volume":"14","author":"Bhavyaa","year":"2021","journal-title":"Int J Clin Pediatr Dent"},{"key":"R3-23-20240828","first-page":"8796425","article-title":"Epistaxis as a common presenting symptom of Glanzmann's thrombasthenia, a rare qualitative platelet disorder: Illustrative case examples","volume":"2017","author":"Recht","year":"2017","journal-title":"Case Rep Emerg Med"},{"key":"R4-23-20240828","doi-asserted-by":"crossref","first-page":"888","DOI":"10.3324\/haematol.2018.214239","article-title":"Glanzmann thrombasthenia: Genetic basis and clinical correlates","volume":"105","author":"Botero","year":"2020","journal-title":"Haematologica"},{"key":"R5-23-20240828","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13023-020-01628-w","article-title":"Diagnostic testing for SARS-CoV-2 infection in HHT patients: nasopharyngeal versus oropharyngeal swab","volume":"15","author":"Pagella","year":"2020","journal-title":"Orphanet Journal of Rare Diseases"},{"key":"R6-23-20240828","doi-asserted-by":"crossref","first-page":"88","DOI":"10.4103\/jiaomr.jiaomr_43_17","article-title":"Glanzmann's Thrombasthenia\u2013A rare case report of spontaneous gingival bleeding","volume":"30","author":"Venkat","year":"2018","journal-title":"J Indian Acad Oral Med Radiol"},{"key":"R7-23-20240828","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.tmrv.2016.01.001","article-title":"New insights into the treatment of Glanzmann Thrombasthenia","volume":"30","author":"Poon","year":"2016","journal-title":"Transfus Med Rev"},{"key":"R8-23-20240828","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1007\/s12663-014-0700-2","article-title":"The effects of topical hemocoagulase solution on the healing process of post-extraction wounds: A split mouth design","volume":"14","author":"Shenoy","year":"2015","journal-title":"J Max Oral Surg"},{"key":"R9-23-20240828","first-page":"9370212","article-title":"Glanzmann's Thrombastenia: The role of tranexamic acid in oral surgery","volume":"2018","author":"Franco","year":"2018","journal-title":"Case Rep Dent"},{"key":"R10-23-20240828","first-page":"443","article-title":"Glanzmann's thrombasthenia: Report of a case and review of the literature","volume":"3","author":"Sebastiano","year":"2010","journal-title":"Int J Clin Exp Pathol"}],"container-title":["Indian Journal of Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijdr.ijdr_1191_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:11:16Z","timestamp":1787757076000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijdr.ijdr_1191_21"}},"subtitle":["Use of Hemocoagulase (BotroClot) for Arrest of Bleeding During a Primary Tooth Endodontic Procedure"],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ijdr.ijdr_1191_21","relation":{},"ISSN":["0970-9290"],"issn-type":[{"value":"0970-9290","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]}}}