{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:38:47Z","timestamp":1786649927942,"version":"build-2736575974"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"\n Background:<\/jats:title>\n Gold is the oldest dental restorative material, used for dental repairs for more than 4000 years, and remains an important metal included in the dental sector. In a world where nanoparticle importance has been well established and preparation of nanoparticles has become much easier, it is important to assess if these nanoparticles can be extracted from plants as well. Along with its extraction, analysis of each property of the nanoparticle is essential. Pepper and eucalyptus remain two of the most important ingredients used in ayurveda and can be easily found as a component in everyday consumption.<\/jats:p>\n <\/jats:sec>\n \n Aim:<\/jats:title>\n This study was to extract gold nanoparticles using eucalyptus and piper longum and evaluate the antibacterial activity of the derived gold nanoparticles.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methodology:<\/jats:title>\n Preparation of plant extract was done following which extraction of gold nanoparticles was performed. Antibacterial properties of the gold nanoparticles were tested by well diffusion method and compared against the antibacterial gold standard, antibiotic amoxicillin. After 24 hours, the zone of inhibitions was measured in millimeters and the data were compiled.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n The resultant green synthesized gold nanoparticles show high antibacterial activity against S. albicans, and a fair amount of antibacterial activity against S. mutans, S. aureus, and E. faecalis, which was revealed by comparing the zone of inhibition to the gold standard, amoxicillin 500 mg.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Gold nanoparticles were found to have good antimicrobial activity.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijdr.ijdr_22_24","type":"journal-article","created":{"date-parts":[[2025,2,15]],"date-time":"2025-02-15T08:00:06Z","timestamp":1739606406000},"page":"429-432","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Green Synthesis of Gold Nanoparticles Using Eucalyptus and Piper Longum and Antimicrobial Activity Evaluation"],"prefix":"10.4103","volume":"35","author":[{"given":"Nadhirah","family":"Faiz","sequence":"first","affiliation":[{"name":"Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Velappanchavadi, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinay","family":"Sivaswamy","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Velappanchavadi, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subhashree","family":"Rohinikumar","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Velappanchavadi, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,2,15]]},"reference":[{"key":"R1-20260423","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2147\/NSA.S3707","article-title":"Gold nanoparticles: From nanomedicine to nanosensing","volume":"1","author":"Chen","year":"2008","journal-title":"Nanotechnol Sci Appl"},{"key":"R3-20260423","doi-asserted-by":"crossref","first-page":"015606.","DOI":"10.1088\/0957-4484\/19\/01\/015606","article-title":"High-yield synthesis and optical response of gold nanostars","volume":"19","author":"Kumar","year":"2007","journal-title":"Nanotechnology"},{"key":"R4-20260423","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1007\/s00405-006-0082-2","article-title":"Behavior of metal implants used in ENT surgery in 7 Tesla magnetic resonance imaging","volume":"263","author":"Thelen","year":"2006","journal-title":"Eur Arch 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gold nanoparticles by novel sundried Cinnamomum camphora leaf","volume":"18","author":"Huang","year":"2007","journal-title":"Nanotechnology"},{"key":"R9-20260423","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1177\/00220345810600040701","article-title":"Materials science: Copper and silver corrosion activity in crown and bridge alloys","volume":"60","author":"Wright","year":"1981","journal-title":"J Dent Res"},{"key":"R10-20260423","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/BF03215496","article-title":"Gold in dentistry: Alloys, uses and performance","volume":"36","author":"Knosp","year":"2003","journal-title":"Gold Bull"},{"key":"R11-20260423","first-page":"52","article-title":"Enhanced antimicrobial activity of herbal formulation mediated copper nanoparticles against clinical pathogens","volume":"21","author":"Rieshy","year":"2020","journal-title":"Plant Cell Biotechnol Mol Biol"},{"key":"R12-20260423","first-page":"33","article-title":"Controlling of oral pathogens using turmeric and tulsi herbal formulation mediated copper nano particles","volume":"21","author":"Kishore","year":"2020","journal-title":"Plant Cell Biotechnol Mol Biol"},{"key":"R13-20260423","first-page":"4452","article-title":"Antibacterial activity of selenium nanoparticles extracted from capparis decidua against escherichia coli and lactobacillus species","volume":"14","author":"Sneka","year":"2021","journal-title":"Res J Pharm Technol"},{"key":"R14-20260423","first-page":"9","article-title":"Antifungal activity of tulsi and turmeric assisted copper nano particle","volume":"21","author":"Roshan","year":"2020","journal-title":"Plant Cell Biotechnol Mol Biol"},{"key":"R15-20260423","first-page":"1670","article-title":"Green synthesis of reduced graphene oxide nanoparticles, its characterization and antimicrobial properties against common oral pathogens","volume":"8","author":"Iffat","year":"2021","journal-title":"Int J Dentistry Oral Sci"},{"key":"R16-20260423","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.colsurfb.2007.01.010","article-title":"A novel extracellular synthesis of monodisperse gold nanoparticles using marine alga, Sargassum wightii Greville","volume":"57","author":"Singaravelu","year":"2007","journal-title":"Colloids Surf B Biointerfaces"},{"key":"R17-20260423","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.saa.2012.09.042","article-title":"Green synthesis of gold nanoparticles using Citrus fruits (Citrus limon, Citrus reticulata and Citrus sinensis) aqueous extract and its characterization","volume":"102","author":"Kannan","year":"2013","journal-title":"Spectrochim Acta A Mol Biomol Spectrosc"},{"key":"R18-20260423","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s13404-012-0048-7","article-title":"The combination effects of trivalent gold ions and gold nanoparticles with different antibiotics against resistant Pseudomonas 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