{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:00:24Z","timestamp":1790420424276,"version":"4.1.0"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"Abstract<\/jats:title>\n \n Skeletal Class III malocclusions are frequently associated with craniosynostosis syndromes, resulting in distinctive facial and dental anomalies. Among these, Crouzon syndrome is characterised by mutations in the\n FGFR2<\/jats:italic>\n gene, leading to premature fusion of the cranial vault, cranial base, orbital and maxillary sutures. The phenotypic expression of this congenital condition varies according to the timing and pattern of sutural fusion. This report details the clinical features and management of a 16-year-old male patient presenting with moderate skeletal Class III malocclusion as a manifestation of Crouzon syndrome. The present case fell within the spectrum of conventional non-surgical management. Adjunctive chin cup therapy initiated after rapid maxillary expansion aided in controlling residual mandibular growth, contributing to a favourable outcome in a hypodivergent pattern. Functional and aesthetic outcomes were markedly enhanced, and the results remained stable at the one-year follow-up assessment. Excellent compliance over 36 months contributed to treatment success and stability.\n <\/jats:p>","DOI":"10.4103\/ijdr.ijdr_46_26","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:00:32Z","timestamp":1790416832000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility of Non-surgical Orthodontic Management in Syndromic Skeletal Class III: A Case Report"],"prefix":"10.4103","author":[{"given":"Snigdha","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopaedics, Faculty of Dental Sciences, King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipti","family":"Shastri","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopaedics, Faculty of Dental Sciences, King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gulshan K.","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopaedics, Faculty of Dental Sciences, King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"R2-20260926","first-page":"26","article-title":"Prevalence of malocclusion and abnormal oral habits in North Indian rural children","volume":"16","author":"Gauba","year":"1998","journal-title":"J Indian Soc Pedod Prev Dent"},{"key":"R3-20260926","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/ng1194-275","article-title":"Jackson-Weiss and Crouzon syndromes are alleilic with mutations in fibroblast growth factor receptor 2","volume":"8","author":"Jabs","year":"1994","journal-title":"Nat Genet"},{"key":"R4-20260926","first-page":"72","article-title":"Non surgical treatment of Crouzon syndrome","volume":"16","author":"Maspero","year":"2014","journal-title":"Stomatologija"},{"key":"R5-20260926","first-page":"394","article-title":"Palatal anomalies in the syndromes of Apert and Crouzon","volume":"11","author":"Peterson","year":"1974","journal-title":"Cleft Palate J"},{"key":"R6-20260926","first-page":"475","article-title":"Treatment of craniosynostosis: The multidisciplinary approach","volume":"31","author":"Fearon","year":"2004","journal-title":"Clin Plast Surg"},{"key":"R7-20260926","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S1073-8746(97)80057-6","article-title":"Facial growth of skeletal class III malocclusion and the effects, limitations, and long-term dentofacial adaptations to chin cup therapy","volume":"3","author":"Sugawara","year":"1997","journal-title":"Semin Orthod"},{"key":"R8-20260926","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1067\/mod.2002.123632","article-title":"Treatment decision in adult patients with class III malocclusion: orthodontic therapy or orthognathic surgery?","volume":"122","author":"Stellzig-Eisenhauer","year":"2002","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"R9-20260926","first-page":"201","article-title":"Non-surgical treatment of mandibular deviation: A case report","volume":"26","author":"Kim","year":"2010","journal-title":"Aust Orthod J"},{"key":"R10-20260926","first-page":"69","article-title":"Treatment of a Class III patient: A case report","volume":"27","author":"Rabie","year":"2011","journal-title":"Aust Orthod J"}],"container-title":["Indian Journal of Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijdr.ijdr_46_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:00:33Z","timestamp":1790416833000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijdr.ijdr_46_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,25]]},"references-count":9,"URL":"https:\/\/doi.org\/10.4103\/ijdr.ijdr_46_26","relation":{},"ISSN":["0970-9290","1998-3603"],"issn-type":[{"value":"0970-9290","type":"print"},{"value":"1998-3603","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,25]]},"assertion":[{"value":"2026-01-16","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}