{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:04:58Z","timestamp":1787169898157,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,4]]},"abstract":"\n The Rationale:<\/jats:title>\n Sarcoidosis is a multisystemic granulomatous disease of unknown aetiology that usually presents with systemic lesions including the skin. Isolated cutaneous lesions are very rare.<\/jats:p>\n <\/jats:sec>\n \n Patient Details:<\/jats:title>\n We present a middle-aged female patient, a known systemic lupus erythematosus patient, in remission developing an isolated, single sarcoidosis lesion in the perioral labial mucosa. The lesion was a rapidly growing nodular lesion with a papillary surface near the philtrum of the upper lip.<\/jats:p>\n <\/jats:sec>\n \n Diagnosis:<\/jats:title>\n A biopsy revealed that to be a granulomatous lesion with large multinucleated giant cells. Using a panel of tests, by excluding tuberculosis and establishing the immunoprofile, the diagnosis was established. Although infrequent, perioral and oral lesions may constitute the first signs of systemic sarcoidosis.<\/jats:p>\n <\/jats:sec>\n \n Outcomes and Take-away Lessons:<\/jats:title>\n For this reason, the oral health care provider needs to be watchful and when there is a suspicion of sarcoidosis, systemic sarcoidosis must be included in the differential diagnosis of oral and perioral granulomatous lesions.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijdr.ijdr_562_21","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T10:42:21Z","timestamp":1637577741000},"page":"261-263","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["A Rare Case Report of Perioral Sarcoidosis"],"prefix":"10.4103","volume":"32","author":[{"given":"S.M.","family":"Balaji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preetha","family":"Balaji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-23-20240828","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/ijd.14218","article-title":"The natural history of cutaneous sarcoidosis. Clinical spectrum and histological analysis of 40 cases","volume":"58","author":"Garc\u00eda-Colmenero","year":"2019","journal-title":"Int J Dermatol"},{"key":"R2-23-20240828","doi-asserted-by":"crossref","first-page":"606461","DOI":"10.3389\/fmed.2020.606461","article-title":"Gene co-expression networks identifies common hub genes between cutaneous sarcoidosis and discoid lupus erythematosus","volume":"7","author":"Nickles","year":"2020","journal-title":"Front Med (Lausanne"},{"key":"R3-23-20240828","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1177\/0961203308100483","article-title":"Co-existing sarcoidosis, systemic lupus erythematosus and the antiphospholipid antibody syndrome: Case reports and discussion from the Brigham and Women's hospital Lupus Center","volume":"18","author":"Wesemann","year":"2009","journal-title":"Lupus"},{"key":"R4-23-20240828","first-page":"549","article-title":"Concurrence of sarcoidosis and systemic lupus erythematosus in three patients","volume":"20","author":"Begum","year":"2002","journal-title":"Clin Exp Rheumatol"},{"key":"R5-23-20240828","doi-asserted-by":"crossref","first-page":"e232093","DOI":"10.1136\/bcr-2019-232093","article-title":"Oral sarcoidosis aiding in diagnosis of underlying systemic disease","volume":"12","author":"Bagchi","year":"2019","journal-title":"BMJ Case Rep"},{"key":"R6-23-20240828","first-page":"180","article-title":"Polymorphic eruption of extensive cutaneous sarcoidosis","volume":"18","author":"Chauhan","year":"2020","journal-title":"Skinmed"},{"key":"R7-23-20240828","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.annder.2017.03.018","article-title":"[Granulomatous periocular eruption]","volume":"144","author":"Moncourier","year":"2017","journal-title":"Ann Dermatol Venereol"},{"key":"R8-23-20240828","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1159\/000493122","article-title":"Micropapular cutaneous sarcoidosis reviewed","volume":"234","author":"Labadie","year":"2018","journal-title":"Dermatology"},{"key":"R9-23-20240828","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1002\/art.41307","article-title":"Lip edema in a young woman\u2013An unusual cause","volume":"72","author":"Sahoo","year":"2020","journal-title":"Arthritis Rheumatol"},{"key":"R10-23-20240828","first-page":"1860","article-title":"Awareness on oral manifestation of sarcoidosis among dental students","volume":"26","author":"Ganapathy","year":"2020","journal-title":"Journal of Contemporary Issues in Business and Government"}],"container-title":["Indian Journal of Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijdr.ijdr_562_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:14:37Z","timestamp":1787166877000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijdr.ijdr_562_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijdr.ijdr_562_21","relation":{},"ISSN":["0970-9290"],"issn-type":[{"value":"0970-9290","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]}}}