{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:33:30Z","timestamp":1787070810594,"version":"build-2736575974"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Denture liners that are made of silicone have a tendency of being colonised by microbes because they are porous and can store moisture thus providing the optimal environment where bacteria and fungi can thrive.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      Sixty silicone discs (Proclinic Expert) were split into six groups (10 discs each), three of which were treated using 5% iodine and three controls in distilled water and assessed against\n                      <jats:italic toggle=\"yes\">Streptococcus mutans<\/jats:italic>\n                      ,\n                      <jats:italic toggle=\"yes\">Lactobacillus salivarius<\/jats:italic>\n                      and\n                      <jats:italic toggle=\"yes\">Candida albicans<\/jats:italic>\n                      . Teams were randomly selected through the computer. Discs were incubated in one week in distilled water, followed by their inoculation. The standard plate count was used to determine the microbial counts (CFU\/ml) after incubating the surface swabbed at 37\u00b0C and an incubation duration of 24\u201348 h. Triple experiments were carried out.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Treatment with 5% iodine solution significantly reduced microbial colony counts for all tested organisms (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.005).\n                      <jats:italic toggle=\"yes\">S. mutans<\/jats:italic>\n                      decreased from 191.4 \u00b1 3.8 to 106.2 \u00b1 2.4 CFU\/ml,\n                      <jats:italic toggle=\"yes\">L. salivarius<\/jats:italic>\n                      from 175.1 \u00b1 2.7 to 86.8 \u00b1 1.8 CFU\/ml, and\n                      <jats:italic toggle=\"yes\">C. albicans<\/jats:italic>\n                      from 115.1 \u00b1 3.9 to 50.0 \u00b1 1.6 CFU\/ml, showing the strongest antifungal effect. These results indicate that 5% iodine is highly effective in reducing microbial colonisation on silicone-based resilient liners.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      The 5% iodine solution demonstrated good antimicrobial action in silicone-based liner contaminated with the oral pathogens in reduction of microbial load\n                      <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                      . But no evaluation was done on the effects on the physical and mechanical properties of the liners.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijdr.ijdr_569_25","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T17:00:09Z","timestamp":1774285209000},"page":"412-416","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Association between the Proportions of Streptococcus mutans, Candida albicans, and Lactobacillus salivarius in Dental Plaques and Dentures"],"prefix":"10.4103","volume":"36","author":[{"given":"Sahar M.","family":"Ahmed","sequence":"first","affiliation":[{"name":"Department of Microbiology, College of Dentistry, AL-Rafidain University, Baghdad, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Entisar M.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Microbiology, College of Medicine, Mustansiriyah University, Baghdad, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esraa","family":"Fuad","sequence":"additional","affiliation":[{"name":"Department of Microbiology, College of Dentistry, AL-Rafidain University, Baghdad, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,3,23]]},"reference":[{"key":"R1-20260325","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/bs.aambs.2023.02.001","article-title":"Biofilm ecology associated with dental caries:Understanding of microbial interactions in oral communities leads to development of therapeutic strategies targeting cariogenic biofilms","volume":"122","author":"Cai","year":"2023","journal-title":"Adv Appl Microbiol"},{"key":"R2-20260325","doi-asserted-by":"crossref","first-page":"2046309","DOI":"10.1080\/20002297.2022.2046309","article-title":"Streptococcus mutans-associated bacteria in dental plaque of severe early childhood caries","volume":"14","author":"Zhang","year":"2022","journal-title":"J Oral Microbiol"},{"key":"R3-20260325","doi-asserted-by":"crossref","first-page":"940602","DOI":"10.3389\/fcimb.2022.940602","article-title":"Streptococcusmutans membrane vesicles enhance candida albicans pathogenicity and carbohydrate metabolism","volume":"12","author":"Wu","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"key":"R4-20260325","doi-asserted-by":"crossref","first-page":"840245","DOI":"10.3389\/fimmu.2022.840245","article-title":"Lactobacillus spp. for gastrointestinal health:Current and future perspectives","volume":"13","author":"Dempsey","year":"2022","journal-title":"Front Immunol"},{"key":"R5-20260325","first-page":"45","article-title":"Candida-associated denture stomatitis. Aetiology and management:A review. Part 1. Factors influencing distribution of Candida species in the oral cavity. Aust","volume":"43","author":"Webb","year":"1998","journal-title":"Dent J"},{"key":"R6-20260325","first-page":"151","article-title":"The significance of Candida albicans in denture stomatitis","volume":"82","author":"Budtz-J\u00f8rgensen","year":"1974","journal-title":"Scand J Dent Res"},{"key":"R7-20260325","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1046\/j.1365-2842.2001.00706.x","article-title":"Candida albicans growth on thermal cycled materials for maxillofacial prostheses in vitro","volume":"28","author":"Nikawa","year":"2001","journal-title":"J Oral Rehabil"},{"key":"R8-20260325","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0109-5641(03)00088-5","article-title":"Colonization and penetration of denture soft lining materials by Candida albicans","volume":"20","author":"Bulad","year":"2004","journal-title":"Dent Mater"},{"key":"R9-20260325","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/0022-3913(87)90026-6","article-title":"Response of processed resilient denture liners to Candida albicans","volume":"57","author":"Burns","year":"1987","journal-title":"J Prosthet Dent"},{"key":"R10-20260325","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1111\/j.1365-2842.1997.tb00379.x","article-title":"Effects of salivary or serum pellicles on the candida albicans growth and biofilm formation on soft lining materials in vitro","volume":"24","author":"Nikawa","year":"1997","journal-title":"J Oral Rehabil"},{"key":"R11-20260325","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.prosdent.2023.09.001","article-title":"Bond strength between denture lining material and CAD-CAM denture base resin:A systematic review and meta-analysis","volume":"134","author":"Pereira","year":"2025","journal-title":"J Prosthet Dent"},{"key":"R12-20260325","doi-asserted-by":"crossref","DOI":"10.21608\/ejmm.2025.405645.1787","article-title":"The role of candida albicans in immune modulation:Biomarkers and cytokine profiles in invasive infections","author":"Al-Ameri","year":"2026","journal-title":"Egypt J Med Microbiol"},{"key":"R13-20260325","doi-asserted-by":"crossref","first-page":"287","DOI":"10.61186\/iem.10.4.287","article-title":"Assessing the prevalence of bacterial vaginosis among infertile women in Thi-Qar Province, Iraq","volume":"10","author":"Mohammad","year":"2024","journal-title":"Infect Epidemiol Microbiol"},{"key":"R14-20260325","doi-asserted-by":"crossref","first-page":"460","DOI":"10.3390\/polym15020460","article-title":"Efficacy of denture cleansers on microbial adherence and surface topography of conventional and CAD\/CAM-processed denture base resins","volume":"15","author":"Alfouzan","year":"2023","journal-title":"Polymers (Basel)"},{"key":"R15-20260325","doi-asserted-by":"crossref","first-page":"e25080","DOI":"10.15421\/0225080","article-title":"The impact of trace elements and cytokines on the pathogenesis and severity of acne","volume":"16","author":"Al-Isawi","year":"2025","journal-title":"Regul Mech Biosyst"},{"key":"R16-20260325","doi-asserted-by":"crossref","first-page":"e25049","DOI":"10.15421\/0225049","article-title":"Bacterial strains isolated from sinusitis infections and their drug resistance profiles in Nasiriyah (Iraq)","volume":"16","author":"Malik","year":"2025","journal-title":"Regul Mech Biosyst"},{"key":"R17-20260325","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbrc.2023.07.048","article-title":"Demonstration of iodide-dependent UVA-triggered growth inhibition in Saccharomyces cerevisiae cells and identification of its suppressive molecules","volume":"677","author":"Ono","year":"2023","journal-title":"Biochem Biophys Res Commun"},{"key":"R18-20260325","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1186\/s12906-021-03323-0","article-title":"Antifungal and anti-biofilm activity of a new Spanish extract of propolis against Candida glabrata","volume":"21","author":"Fern\u00e1ndez-Calder\u00f3n","year":"2021","journal-title":"BMC Complement Med Ther"},{"key":"R19-20260325","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/adj.12312","article-title":"Inhibitory effects of antiseptic mouthrinses on streptococcus mutans, streptococcus sanguinis and lactobacillus acidophilus","volume":"60","author":"Evans","year":"2015","journal-title":"Aust Dent J"},{"key":"R20-20260325","first-page":"260","article-title":"Iodine induces toxicity against Candida albicans and Candida glabrata through oxidative stress","volume":"14","author":"Cuellar-Rufino","year":"2022","journal-title":"Iran J Microbiol"}],"container-title":["Indian Journal of Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijdr.ijdr_569_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:36:58Z","timestamp":1787067418000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijdr.ijdr_569_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ijdr.ijdr_569_25","relation":{},"ISSN":["0970-9290","1998-3603"],"issn-type":[{"value":"0970-9290","type":"print"},{"value":"1998-3603","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"2025-08-05","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-24","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}