{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:32:06Z","timestamp":1787776326192,"version":"build-2784847793"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Alzheimer\u2019s disease (AD) is a progressive neurodegenerative disorder characterised by the loss of intellectual functions. The disorder is usually seen after the age of 60 years, and these elderly patients tend to experience a progressive decline in their cognitive and behavioural abilities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>The present study was carried out to assess the oral health-related quality of life (OHRQoL) in elderly patients suffering from AD as compared to subjects without the disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Method:<\/jats:title>\n                    <jats:p>One hundred elderly subjects with AD and 150 subjects without AD were included in the study. The subjective assessment of OHRQoL was done using the General Oral Health Assessment Index (GOHAI). Demographic and oral characteristics were assessed for dentition status with the Decayed, Missing and Filled Teeth (DMFT) index, Oral Hygiene Index (OHI), prosthesis use, xerostomia and presence of oral pathologies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      GOHAI values were found to be statistically higher (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0003) in the subjects with AD. The subjects with AD were found to have a higher DMFT (mean difference = 4.11), Oral Hygiene Index (OHI) scores (mean difference = 1.54), xerostomia (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0128) and number of oral pathologies. However, the educational level (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.2603) and number of natural teeth (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0006) were found to be lower in the group with AD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The present study reported that the elderly subjects suffering from AD had poorer OHRQoL than those without the disease. There is a need to comprehensively evaluate the oral health conditions of elderly patients with AD and actively provide management to improve their OHRQoL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijdr.ijdr_792_21","type":"journal-article","created":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T07:03:37Z","timestamp":1726470217000},"page":"149-153","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Oral Health-Related Quality of Life (OHRQoL) in Elderly Patients with and without Alzheimer\u2019s Disease - An Evaluative Study"],"prefix":"10.4103","volume":"35","author":[{"given":"Ambar","family":"Khan","sequence":"first","affiliation":[{"name":"Department of Public Health Dentistry, College of Dental Science and Hospital, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafia","family":"Untoo","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, D.J. College of Dental Sciences and Research, Modinagar, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basavaraj","family":"Patthi","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, D.J. College of Dental Sciences and Research, Modinagar, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish","family":"Singla","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, D.J. College of Dental Sciences and Research, Modinagar, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Kumari","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, Dental College Azamgarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ananthalekshmy","family":"Rajeev","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, The Oxford Dental College, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,9,14]]},"reference":[{"key":"R2-20241009","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1056\/NEJMra040223","article-title":"Alzheimer's disease","volume":"35","author":"Cummings","year":"2004","journal-title":"N Engl J Med"},{"key":"R3-20241009","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.14219\/jada.archive.2006.0381","article-title":"Alzheimer's disease:Psychopathology, medical management and dental implications","volume":"137","author":"Friedlander","year":"2006","journal-title":"J Am Dent Assoc"},{"key":"R4-20241009","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0378-5122(98)00110-8","article-title":"Alzheimer's disease","volume":"15","author":"Reiman","year":"1999","journal-title":"Maturitas"},{"key":"R5-20241009","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1067\/moe.2002.123538","article-title":"Alzheimer's disease and dental management","volume":"93","author":"Kocaelli","year":"2002","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R6-20241009","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/j.1741-2358.2003.00078.x","article-title":"Association between dental health behaviours, mental\/physical function and self-feeding ability among the elderly:A cross-sectional survey","volume":"20","author":"Arai","year":"2003","journal-title":"Gerodontology"},{"key":"R7-20241009","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/S0011-8532(22)00051-9","article-title":"Providing dental care for patients diagnosed with Alzheimer's disease","volume":"41","author":"Henry","year":"1997","journal-title":"Dent Clin North Am"},{"key":"R8-20241009","doi-asserted-by":"crossref","first-page":"659","DOI":"10.2147\/CIA.S125128","article-title":"Oral health-related quality of life and prosthetic status of nursing home residents with or without dementia","volume":"12","author":"Klotz","year":"2017","journal-title":"Clin Interv Aging"},{"key":"R9-20241009","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1212\/WNL.57.6.985","article-title":"Incidence of Alzheimer's disease in a rural community in India:The Indo\u2013US study","volume":"57","author":"Chandra","year":"2001","journal-title":"Neurology"},{"key":"R10-20241009","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1002\/j.0022-0337.1990.54.11.tb02481.x","article-title":"Development of the geriatric oral health assessment index","volume":"54","author":"Atchison","year":"1990","journal-title":"J Dent Educ"},{"key":"R11-20241009","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/ger.12099","article-title":"Translation and validation of Hindi version of Geriatric Oral Health Assessment Index","volume":"33","author":"Mathur","year":"2016","journal-title":"Gerodontology"},{"key":"R12-20241009","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1741-2358.2006.00118.x","article-title":"The oral health of individuals with dementia in nursing homes","volume":"23","author":"Adam","year":"2006","journal-title":"Gerodontology"},{"key":"R14-20241009","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1212\/WNL.46.3.641","article-title":"Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study:What is in store for the oldest old?","volume":"46","author":"Lautenschlager","year":"1996","journal-title":"Neurology"},{"key":"R15-20241009","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.oooo.2012.03.028","article-title":"Oral health of the elderly with Alzheimer's disease","volume":"114","author":"Ribeiro","year":"2012","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"R16-20241009","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.prosdent.2017.07.010","article-title":"Mastication and oral health\u2013related quality of life in removable denture wearers with Alzheimer disease","volume":"119","author":"Campos","year":"2018","journal-title":"J Prosthet Dent"},{"key":"R17-20241009","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/scd.12178","article-title":"Oral health-related quality of life in mild Alzheimer:patient versus caregiver perceptions","volume":"36","author":"Campos","year":"2016","journal-title":"Spec Care Dentist"},{"key":"R18-20241009","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1590\/S0102-311X2005000400028","article-title":"Self-perception and oral health conditions in an elderly population (Portuguese)","volume":"21","author":"Silva","year":"2005","journal-title":"Cad Saude Publica"},{"key":"R19-20241009","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.prosdent.2019.08.015","article-title":"Association of oral health\u2013related quality of life and Alzheimer disease:A systematic review","volume":"124","author":"Ming","year":"2019","journal-title":"J Prosthet Dent"},{"key":"R20-20241009","doi-asserted-by":"crossref","first-page":"184","DOI":"10.17126\/joralres.2014.043","article-title":"Alzheimer's disease:Oral manifestations, treatment and preventive measures","volume":"3","author":"Ortega-Mart\u00ednez","year":"2014","journal-title":"J Oral Res"}],"container-title":["Indian Journal of Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijdr.ijdr_792_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:06:32Z","timestamp":1787774792000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijdr.ijdr_792_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ijdr.ijdr_792_21","relation":{},"ISSN":["0970-9290","1998-3603"],"issn-type":[{"value":"0970-9290","type":"print"},{"value":"1998-3603","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"2021-08-07","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}