{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:42:01Z","timestamp":1786653721470,"version":"build-2736575974"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Pituitary microadenomas are said to be common, with an incidence of 27%. Hypothyroidism causing periorbital oedema (PO) remains rare in the literature, but it is still within the etiological factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient Concerns:<\/jats:title>\n                    <jats:p>This study presents a 53-year-old patient who presented with PO and visited the dental clinic to exclude dental infection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Diagnosis:<\/jats:title>\n                    <jats:p>Based on the evaluation of proper haematological and radiological investigations, pituitary microadenoma was identified with an abrupt increase in the thyroid stimulating hormone (TSH) level.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Follow-up:<\/jats:title>\n                    <jats:p>The patient was followed with further studies to identify the primary cause of PO. It was concluded that the disruption in the drug regimen caused an increase in the TSH and led to PO rather than microadenoma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijdr.ijdr_9_22","type":"journal-article","created":{"date-parts":[[2024,4,20]],"date-time":"2024-04-20T12:01:03Z","timestamp":1713614463000},"page":"455-457","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Periorbital Oedema Associated with Hypothyroidism \u2013 A Case Report"],"prefix":"10.4103","volume":"34","author":[{"given":"Bushra R.","family":"Noaman","sequence":"first","affiliation":[{"name":"Department of Pedodontics, Faculty of Dentistry, Tishk International University, Erbil, Kurdistan Region, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah M.","family":"Bazrgan","sequence":"additional","affiliation":[{"name":"Department of Pedodontics, Faculty of Dentistry, Tishk International University, Erbil, Kurdistan Region, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,4,19]]},"reference":[{"key":"R1-20250715","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1007\/s11102-019-00988-2","article-title":"A tale of pituitary adenomas: To NET or not to NET","volume":"22","author":"Ho","year":"2019","journal-title":"Pituitary"},{"issue":"3 Suppl 1","key":"R2-20250715","first-page":"56","article-title":"Pituitary adenomas: A review","volume":"4","author":"Sharif-Alhoseini","year":"2012","journal-title":"J Inj Violence Res"},{"key":"R3-20250715","doi-asserted-by":"crossref","first-page":"151","DOI":"10.2214\/ajr.144.1.151","article-title":"Prolactin-secreting pituitary microadenomas: Inaccuracy of high-resolution CT imaging","volume":"1","author":"Davis","year":"1985","journal-title":"AJR Am J Roentgenol"},{"key":"R4-20250715","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1148\/radiology.161.3.3786729","article-title":"Pituitary adenomas: High-resolution MR imaging at 1.5 T","volume":"3","author":"Kucharczyk","year":"1986","journal-title":"Radiology"},{"key":"R5-20250715","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1089\/thy.2012.0205","article-title":"American Association of Clinical Endocrinologists and American Thyroid Association Taskforce on Hypothyroidism in Adults. Clinical practice guidelines for hypothyroidism in adults: Cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association","volume":"12","author":"Garber","year":"2012","journal-title":"Thyroid"},{"key":"R7-20250715","article-title":"Clinical manifestations and evaluation of edema in adults","author":"Smith","year":"2019","journal-title":"United States: UptoDate"},{"key":"R8-20250715","doi-asserted-by":"crossref","first-page":"184","DOI":"10.3389\/fendo.2017.00184","article-title":"Not all orbitopathy is Graves\u2019: Discussion of cases and review of literature","volume":"8","author":"Boddu","year":"2017","journal-title":"Front Endocrinol (Lausanne)"},{"key":"R9-20250715","first-page":"364","article-title":"Periorbital oedema caused by profound primary hypothyroidism","author":"Martin","year":"2019","journal-title":"BMJ: British Medical Journal (Online)"}],"container-title":["Indian Journal of Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijdr.ijdr_9_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:41:24Z","timestamp":1786650084000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijdr.ijdr_9_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ijdr.ijdr_9_22","relation":{},"ISSN":["0970-9290","1998-3603"],"issn-type":[{"value":"0970-9290","type":"print"},{"value":"1998-3603","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"2022-01-06","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-14","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}