{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:12:39Z","timestamp":1792033959775,"version":"4.4.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T00:00:00Z","timestamp":1612483200000},"content-version":"vor","delay-in-days":1406,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Indian Journal of Medical Microbiology"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.4103\/ijmm.ijmm_17_47","type":"journal-article","created":{"date-parts":[[2020,12,7]],"date-time":"2020-12-07T08:51:17Z","timestamp":1607331077000},"page":"237-242","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Evaluation of Serum Galactomannan Enzyme Immunoassay at Two Different Cut-offs for the Diagnosis of Invasive Aspergillosis in Patients with Febrile Neutropenia"],"prefix":"10.1016","volume":"35","author":[{"given":"Ritin","family":"Mohindra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malini R.","family":"Capoor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shikha","family":"Puri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitesh","family":"Raheja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinesh K.","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranadip","family":"Chowdhury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.4103\/ijmm.IJMM_17_47_bib1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1086\/323335","article-title":"Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: An international consensus","volume":"34","author":"Ascioglu","year":"2002","journal-title":"Clin Infect Dis"},{"key":"10.4103\/ijmm.IJMM_17_47_bib2","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1128\/CMR.18.1.44-69.2005","article-title":"Aspergillus infections in transplant recipients","volume":"18","author":"Singh","year":"2005","journal-title":"Clin Microbiol Rev"},{"key":"10.4103\/ijmm.IJMM_17_47_bib3","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/00005792-199903000-00003","article-title":"Invasive aspergillosis in transplant recipients","volume":"78","author":"Paterson","year":"1999","journal-title":"Medicine (Baltimore)"},{"issue":"Suppl 1","key":"10.4103\/ijmm.IJMM_17_47_bib4","doi-asserted-by":"crossref","first-page":"S239","DOI":"10.1080\/13693780400025161","article-title":"Invasive aspergillosis in the hematologic and immunologic patient: New findings and key questions in leukemia","volume":"43","author":"Herbrecht","year":"2005","journal-title":"Med Mycol"},{"key":"10.4103\/ijmm.IJMM_17_47_bib5","doi-asserted-by":"crossref","first-page":"34","DOI":"10.4103\/0255-0857.108717","article-title":"Variables affecting the performance of galactomannan assay in high-risk patients at a tertiary care centre in India","volume":"31","author":"Khanna","year":"2013","journal-title":"Indian J Med Microbiol"},{"key":"10.4103\/ijmm.IJMM_17_47_bib6","first-page":"86","article-title":"Detection of galactomannan and (1-3)-\u03b2-D-glucan for early diagnosis of invasive aspergillosis in hematological cancer patients","volume":"9","author":"Xin","year":"2013","journal-title":"Int J Pharmacol"},{"key":"10.4103\/ijmm.IJMM_17_47_bib7","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ijid.2016.10.027","article-title":"Utility of the serum galactomannan assay for the diagnosis of invasive aspergillosis in children with acute lymphoblastic leukemia","volume":"54","author":"Avcu","year":"2017","journal-title":"Int J Infect Dis"},{"key":"10.4103\/ijmm.IJMM_17_47_bib8","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1093\/annonc\/mdm571","article-title":"Aspergillus galactomannan testing in patients with long-term neutropenia: Implications for clinical management","volume":"19","author":"Penack","year":"2008","journal-title":"Ann Oncol"},{"key":"10.4103\/ijmm.IJMM_17_47_bib9","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/sj.bmt.1703332","article-title":"Late onset of invasive aspergillus infection in bone marrow transplant patients at a university hospital","volume":"29","author":"Grow","year":"2002","journal-title":"Bone Marrow Transplant"},{"key":"10.4103\/ijmm.IJMM_17_47_bib10","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1086\/425317","article-title":"Utility of Aspergillus antigen detection in specimens other than serum specimens","volume":"39","author":"Klont","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.4103\/ijmm.IJMM_17_47_bib11","doi-asserted-by":"crossref","first-page":"74","DOI":"10.4103\/0971-5851.116181","article-title":"Serum galactomannan assay for diagnosis of probable invasive aspergillosis in acute leukemia and hematopoietic stem cell transplantation","volume":"34","author":"Ghosh","year":"2013","journal-title":"Indian J Med Paediatr Oncol"},{"key":"10.4103\/ijmm.IJMM_17_47_bib12","first-page":"158","article-title":"Rapid diagnosis of invasive aspergillosis by antigen","volume":"5","author":"Wheat","year":"2003","journal-title":"J Clin Infect Dis"},{"key":"10.4103\/ijmm.IJMM_17_47_bib13","series-title":"Aspergillosis. Fundamental Medical Mycology","first-page":"357","year":"2012"},{"key":"10.4103\/ijmm.IJMM_17_47_bib14","first-page":"1","article-title":"Galactomannan and 1, 3-D-Glucan testing for the diagnosis of invasive aspergillosis","volume":"22","author":"Lamoth","year":"2016","journal-title":"J Fungi"},{"key":"10.4103\/ijmm.IJMM_17_47_bib15","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.1128\/JCM.37.10.3223-3228.1999","article-title":"Autopsy-controlled prospective evaluation of serial screening for circulating galactomannan by a sandwich enzyme-linked immunosorbent assay for haematological patients at risk for invasive aspergillosis","volume":"37","author":"Maertens","year":"1999","journal-title":"J Clin Microbiol"},{"key":"10.4103\/ijmm.IJMM_17_47_bib16","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1182\/blood.V97.6.1604","article-title":"Screening for circulating Galactomannan as a non-invasive diagnostic tool for invasive aspergillosis in prolonged neutropenic patients and stem cell transplantation recipients: A prospective validation","volume":"97","author":"Maertens","year":"2001","journal-title":"J Blood"},{"key":"10.4103\/ijmm.IJMM_17_47_bib17","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1086\/343804","article-title":"Use of circulating galactomannan screening for early diagnosis of invasive aspergillosis in allogeneic stem cell transplant recipients","volume":"186","author":"Maertens","year":"2002","journal-title":"J Infect Dis"},{"key":"10.4103\/ijmm.IJMM_17_47_bib18","first-page":"459405","article-title":"Laboratory diagnosis of invasive aspergillosis: From diagnosis to prediction of outcome","volume":"2013","author":"Barton","year":"2013","journal-title":"Scientifica (Cairo)"},{"key":"10.4103\/ijmm.IJMM_17_47_bib19","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1086\/503427","article-title":"Diagnosis of invasive aspergillosis using a galactomannan assay: A meta-analysis","volume":"42","author":"Pfeiffer","year":"2006","journal-title":"Clin Infect Dis"},{"key":"10.4103\/ijmm.IJMM_17_47_bib20","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1086\/514349","article-title":"Optimization of the cutoff value for the Aspergillus double-sandwich enzyme immunoassay","volume":"44","author":"Maertens","year":"2007","journal-title":"Clin Infect Dis"},{"key":"10.4103\/ijmm.IJMM_17_47_bib21","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1128\/JCM.43.1.299-305.2005","article-title":"Contribution of (1\u21923)-beta-D-glucan chromogenic assay to diagnosis and therapeutic monitoring of invasive aspergillosis in neutropenic adult patients: A comparison with serial screening for circulating galactomannan","volume":"43","author":"Pazos","year":"2005","journal-title":"J Clin Microbiol"},{"key":"10.4103\/ijmm.IJMM_17_47_bib22","first-page":"743","article-title":"Early diagnosis of invasive aspergillosis in neutropenic patients with biweekly serial screening of circulating galactomannan by Platelet antigen","volume":"19","author":"Palaceo","year":"2006","journal-title":"J Clin Infect Dis"},{"key":"10.4103\/ijmm.IJMM_17_47_bib23","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1128\/JCM.41.5.2184-2186.2003","article-title":"Detection of circulating Aspergillus fumigatus galactomannan: Value and limits of the Platelia test for diagnosing invasive aspergillosis","volume":"41","author":"Pinel","year":"2003","journal-title":"J Clin Microbiol"},{"key":"10.4103\/ijmm.IJMM_17_47_bib24","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1046\/j.1365-2141.2003.04308.x","article-title":"Galactomannan detection in computerized tomography-based broncho-alveolar lavage fluid and serum in haematological patients at risk for invasive pulmonary aspergillosis","volume":"121","author":"Becker","year":"2003","journal-title":"Br J Haematol"},{"key":"10.4103\/ijmm.IJMM_17_47_bib25","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1093\/infdis\/155.5.1005","article-title":"Receptor-mediated clearance of Aspergillus galactomannan","volume":"155","author":"Bennett","year":"1987","journal-title":"J Infect Dis"},{"key":"10.4103\/ijmm.IJMM_17_47_bib26","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s11046-007-9010-2","article-title":"Update on the contribution of galactomannan for the diagnosis of invasive aspergillosis","volume":"163","author":"Aquino","year":"2007","journal-title":"Mycopathologia"},{"key":"10.4103\/ijmm.IJMM_17_47_bib27","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1056\/NEJM200312113492424","article-title":"False positive test for Aspergillus antigenemia related to concomitant administration of piperacillin and tazobactam","volume":"349","author":"Sulahian","year":"2003","journal-title":"N Engl J Med"},{"key":"10.4103\/ijmm.IJMM_17_47_bib28","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1111\/j.1600-6143.2004.00415.x","article-title":"Prospective assessment of platelia Aspergillus galactomannan antigen for the diagnosis of invasive aspergillosis in lung transplant recipients","volume":"4","author":"Husain","year":"2004","journal-title":"Am J Transplant"},{"key":"10.4103\/ijmm.IJMM_17_47_bib29","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1164\/rccm.200704-606OC","article-title":"Galactomannan in bronchoalveolar lavage fluid: A tool for diagnosing aspergillosis in Intensive Care Unit patients","volume":"177","author":"Meersseman","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"10.4103\/ijmm.IJMM_17_47_bib30","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1086\/647935","article-title":"Bronchoalveolar lavage fluid galactomannan for the diagnosis of invasive pulmonary aspergillosis in patients with hematologic diseases","volume":"49","author":"Maertens","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.4103\/ijmm.IJMM_17_47_bib31","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s12185-009-0429-8","article-title":"Detection of sputum Aspergillus galactomannan for diagnosis of invasive pulmonary aspergillosis in haematological patients","volume":"90","author":"Kimura","year":"2009","journal-title":"Int J Hematol"},{"key":"10.4103\/ijmm.IJMM_17_47_bib32","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/1471-2334-10-44","article-title":"Galactomannan testing of bronchoalveolar lavage fluid is useful for diagnosis of invasive pulmonary aspergillosis in hematology patients","volume":"10","author":"Hsu","year":"2010","journal-title":"BMC Infect Dis"},{"key":"10.4103\/ijmm.IJMM_17_47_bib33","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/j.rmed.2013.04.007","article-title":"The utility of galactomannan antigen in the bronchial washing and serum for diagnosing pulmonary aspergillosis","volume":"107","author":"Kono","year":"2013","journal-title":"Respir Med"},{"key":"10.4103\/ijmm.IJMM_17_47_bib34","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1186\/s12879-015-1014-9","article-title":"Serum galactomannan index for early prediction of mortality in immunocompromised children with invasive pulmonary aspergillosis","volume":"15","author":"Han","year":"2015","journal-title":"BMC Infect Dis"},{"key":"10.4103\/ijmm.IJMM_17_47_bib35","first-page":"943691","article-title":"The diagnosis of invasive and noninvasive pulmonary aspergillosis by serum and bronchoalveolar lavage fluid galactomannan assay","volume":"2015","author":"Zhang","year":"2015","journal-title":"Biomed Res Int"},{"key":"10.4103\/ijmm.IJMM_17_47_bib36","doi-asserted-by":"crossref","first-page":"899","DOI":"10.3904\/kjim.2015.30.6.899","article-title":"Serum galactomannan levels in the diagnosis of invasive aspergillosis","volume":"30","author":"Okuturlar","year":"2015","journal-title":"Korean J Intern Med"},{"key":"10.4103\/ijmm.IJMM_17_47_bib37","first-page":"DC01","article-title":"Galactomannan assay and invasive pulmonary aspergillosis-Comparison of the test performance at an in-house and the Kit cut-off","volume":"10","author":"Savio","year":"2016","journal-title":"J Clin Diagn Res"}],"container-title":["Indian Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0255085720302905?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0255085720302905?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T19:17:04Z","timestamp":1759346224000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0255085720302905"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["S0255085720302905"],"URL":"https:\/\/doi.org\/10.4103\/ijmm.ijmm_17_47","relation":{},"ISSN":["0255-0857"],"issn-type":[{"value":"0255-0857","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of Serum Galactomannan Enzyme Immunoassay at Two Different Cut-offs for the Diagnosis of Invasive Aspergillosis in Patients with Febrile Neutropenia","name":"articletitle","label":"Article Title"},{"value":"Indian Journal of Medical Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.4103\/ijmm.IJMM_17_47","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2017 Indian Journal of Medical Microbiology. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}