{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:08:22Z","timestamp":1790734102811,"version":"4.1.0"},"reference-count":23,"publisher":"Scientific Scholar","issue":"5&6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,5]]},"abstract":"\n Background & objectives:<\/jats:title>\n The COVID-19 pandemic had a distinct impact on scientific research and Ethics Committees (ECs). We conducted a mixed-methods investigation to understand the issues faced and solutions identified by ECs during this pandemic in India.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n A quantitative online survey form (30 members) and qualitative in-depth interviews (10 members) from various ECs were conducted. Thematic content analysis for qualitative and proportion analysis for quantitative data was carried out.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n During the online survey, an average difficulty score, which was measured using the Visual Analogue Scale, was 5.3 (SD 2.1). Pressure for expedited approvals was felt by EC members with a drastic increase in the number of submission of research projects. The scarcity of information on investigational products (IPs) and requisite consent process posed major hurdles. Ongoing non-COVID studies and post-graduate dissertations were badly hit due to the shift in attention towards COVID-related research. Non-familiarity with virtual technology and lack of face-to-face interactions were highlighted as demerits. However, a few of the EC members welcomed newer methods, being time-saving, convenient and reducing travel hassles. Site monitoring and severe adverse event-related analyses were also negatively impacted upon. Solutions included the alternate methods of consenting (virtual, abbreviated), a detailed explanation of the protocol and IPs and benefits versus risk assessment.<\/jats:p>\n <\/jats:sec>\n \n Interpretation & conclusions:<\/jats:title>\n Despite various challenges posed by the COVID-19 pandemic, the ECs in India steered well through the hurdles. Moreover, adapting a hybrid mode, technical training and updating guidelines were perceived as urgent by EC members.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijmr.ijmr_1095_22","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T07:10:47Z","timestamp":1665990647000},"page":"461-471","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":11,"title":["Challenges faced by ethics committee members in India during COVID-19 pandemic: A mixed-methods exploration"],"prefix":"10.25259","volume":"155","author":[{"given":"Abhijit Vasantrao","family":"Kadam","sequence":"first","affiliation":[{"name":"Division of Clinical Sciences, ICMR-National AIDS Research Institute, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandip","family":"Patil","sequence":"additional","affiliation":[{"name":"Division of Clinical Sciences, ICMR-National AIDS Research Institute, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suvarna","family":"Sane","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, ICMR-National AIDS Research Institute, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.M.","family":"Shahabuddin","sequence":"additional","affiliation":[{"name":"Division of Library, ICMR-National AIDS Research Institute, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samiran","family":"Panda","sequence":"additional","affiliation":[{"name":"Division of Epidemiology and Communicable Diseases, Indian Council of Medical Research, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2022,10,28]]},"reference":[{"key":"B1-20241212","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/1747016120941632","article-title":"Fostering ethical biomedical 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