{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T05:12:39Z","timestamp":1774242759281,"version":"3.50.1"},"reference-count":11,"publisher":"Scientific Scholar","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,3]]},"abstract":"\n \n The incidence of carbapenem-resistant Enterobacteriaceae<\/jats:italic> has been steadily rising. The morbidity, mortality and financial implications of such patients are significant. We did a retrospective analysis of the case records of 11 patients who had culture report positive for pan drug-resistant (PDR) organisms. There were total 15 isolates of PDR organisms in 11 patients. These were associated with catheter-associated urinary tract infections (7), tracheitis (4), bacteraemia (2), meningitis (1) and soft-tissue infection (1). Average APACHE II score was 23.72 (range 7-36) indicating patients with multiple co-morbidities and organ dysfunction. The average length of hospital stay was 60.72 (25-123) days. The overall mortality rate was 81.81 per cent, while PDR infection-related mortality was 18.18 per cent. Strict implementation of antibiotic stewardship programme is essential to limit use and prevent abuse of colistin.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijmr.ijmr_1388_17","type":"journal-article","created":{"date-parts":[[2019,6,24]],"date-time":"2019-06-24T08:11:27Z","timestamp":1561363887000},"page":"418-422","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":13,"title":["Retrospective analysis of colistin-resistant bacteria in a tertiary care centre in India"],"prefix":"10.25259","volume":"149","author":[{"given":"Sharmili","family":"Sinha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suneeta","family":"Sahu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyotirmaya","family":"Pati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Banambar","family":"Ray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saroj Kumar","family":"Pattnaik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","reference":[{"key":"R1-19-20241212","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1093\/jac\/dkl562","article-title":"Colistin-resistant isolates of Klebsiella pneumoniae emerging in Intensive Care Unit patients: First report of a multiclonal cluster","volume":"59","author":"Antoniadou","year":"2007","journal-title":"J Antimicrob Chemother"},{"key":"R2-19-20241212","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1128\/AAC.01020-10","article-title":"Outbreak of colistin-resistant, carbapenem-resistant Klebsiella pneumoniae in metropolitan detroit, michigan","volume":"55","author":"Marchaim","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"key":"R3-19-20241212","doi-asserted-by":"crossref","first-page":"86","DOI":"10.5799\/ahinjs.02.2014.03.0145","article-title":"Emergence of pan-drug resistance amongst gram negative bacteria! 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