{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:57:27Z","timestamp":1782889047746,"version":"3.54.5"},"reference-count":28,"publisher":"Scientific Scholar","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:sec>\n            <jats:title>Background &amp; objectives:<\/jats:title>\n            <jats:p>Magnetic resonance imaging (MRI) is frequently done for the evaluation of chronic low backache (CLBA), however, its significance in Indian patients has not been evaluated. We report here the MRI findings in patients with CLBA and their sensitivity and specificity with clinical evidence of radiculopathy and localized CLBA as well as correlate these with pain severity and disability.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Seventy two patients with CLBA aged 20-70 yr without trauma, infection, tumour, metastasis and vascular malformation were included in the study. Their demographic characteristics, lifestyle, education and employment were noted. Lumbosacral MRI was carried out and 19 MRI parameters at six levels (D12-L1-L5-S1) were noted. The severity of pain was assessed by Numeric Rating Scale (NRS, 0-10) and disability by Oswestry Disability Index (ODI).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>MRI was abnormal in all patients, the most common being disc desiccation (90.3%) followed by facet joint arthropathy (FJA; 75%) and nerve root compression (NRC; 72.2%). Endplate changes and high-intensity zone were noted in 58 and 50 per cent of patients, respectively. One-third patients with FJA, however, were below 30 yr of age. NRC on MRI had 61.3 per cent sensitivity and 10 per cent specificity with clinical radiculopathy. FJA had 60.7 per cent sensitivity and 15.9 per cent specificity with localized CLBA. None of the MRI parameters and MRI sum score correlated with NRS and ODI. On multivariate analysis, NRS was independent predictor of ODI (odds ratio 0.58, 95% confidence interval 0.35-0.98, <jats:italic toggle=\"yes\">P<\/jats:italic>=0.04).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Interpretation &amp; conclusions:<\/jats:title>\n            <jats:p>In patients with CLBA, NRC on MRI showed poor specificity with corresponding clinical radiculopathy and FJA with localized backache. None of the MRI abnormality correlated with the severity of pain or disability.<\/jats:p>\n          <\/jats:sec>","DOI":"10.4103\/ijmr.ijmr_1653_14","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T12:46:48Z","timestamp":1519217208000},"page":"796-803","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Clinical significance of magnetic resonance imaging findings in chronic low backache"],"prefix":"10.25259","volume":"145","author":[{"given":"A.K.","family":"Kohat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayantee","family":"Kalita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Ramanivas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usha K.","family":"Misra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.V.","family":"Phadke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","reference":[{"key":"R1-15-20241212","doi-asserted-by":"crossref","first-page":"2724","DOI":"10.1097\/01.brs.0000244618.06877.cd","article-title":"Back pain prevalence and visit rates: Estimates from U.S. national surveys, 2002","volume":"31","author":"Deyo","year":"2006","journal-title":"Spine (Phila Pa 1976"},{"key":"R2-15-20241212","first-page":"16","article-title":"Disability related to chronic low back pain: Prevalence and associated factors","volume":"46","author":"Salvetti Mde","year":"2012","journal-title":"Rev Esc Enferm USP"},{"key":"R3-15-20241212","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1056\/NEJM199407143310201","article-title":"Magnetic resonance imaging of the lumbar spine in people without back pain","volume":"331","author":"Jensen","year":"1994","journal-title":"N Engl J Med"},{"key":"R4-15-20241212","first-page":"141","article-title":"Correlation of clinical presentation, radiography, and magnetic resonance imaging for low back pain \u2013 A preliminary survey","volume":"6","author":"Yong","year":"2003","journal-title":"J HK Coll Radiol"},{"key":"R5-15-20241212","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1259\/0007-1285-65-773-361","article-title":"High-intensity zone: A diagnostic sign of painful lumbar disc on magnetic resonance imaging","volume":"65","author":"Aprill","year":"1992","journal-title":"Br J Radiol"},{"key":"R6-15-20241212","doi-asserted-by":"crossref","first-page":"598","DOI":"10.7326\/0003-4819-112-8-598","article-title":"Herniated lumbar intervertebral disk","volume":"112","author":"Deyo","year":"1990","journal-title":"Ann Intern Med"},{"key":"R7-15-20241212","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1097\/BRS.0b013e318184ef95","article-title":"Facet joint osteoarthritis and low back pain in the community-based population","volume":"33","author":"Kalichman","year":"2008","journal-title":"Spine (Phila Pa 1976"},{"key":"R8-15-20241212","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.jns.2014.05.002","article-title":"An open labeled randomized controlled trial of pregabalin versus amitriptyline in chronic low backache","volume":"342","author":"Kalita","year":"2014","journal-title":"J Neurol Sci"},{"key":"R9-15-20241212","first-page":"1067","article-title":"Chronic low back pain: Evaluation and management","volume":"79","author":"Last","year":"2009","journal-title":"Am Fam Physician"},{"key":"R10-15-20241212","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1136\/bmj.328.7448.1119","article-title":"Low back pain","volume":"328","author":"Speed","year":"2004","journal-title":"BMJ"},{"key":"R12-15-20241212","doi-asserted-by":"crossref","first-page":"2940","DOI":"10.1097\/00007632-200011150-00017","article-title":"The Oswestry disability index","volume":"25","author":"Fairbank","year":"2000","journal-title":"Spine (Phila Pa 1976"},{"key":"R13-15-20241212","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1002\/mus.880170603","article-title":"Osteomalacic myopathy","volume":"17","author":"Russell","year":"1994","journal-title":"Muscle Nerve"},{"key":"R14-15-20241212","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1097\/00007632-199901010-00011","article-title":"Differentiating lumbar disc protrusions, disc bulges, and discs with normal contour but abnormal signal intensity. Magnetic resonance imaging with discographic correlations","volume":"24","author":"Milette","year":"1999","journal-title":"Spine (Phila Pa 1976"},{"key":"R15-15-20241212","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1148\/radiology.165.2.3659376","article-title":"Normal and degenerative posterior spinal structures: MR imaging","volume":"165","author":"Grenier","year":"1987","journal-title":"Radiology"},{"key":"R16-15-20241212","first-page":"371","article-title":"Spondylolisthesis","volume":"54","author":"Meyerding","year":"1932","journal-title":"Surg Gynecol Obstet"},{"key":"R18-15-20241212","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1148\/radiology.166.1.3336678","article-title":"Degenerative disk disease: Assessment of changes in vertebral body marrow with MR imaging","volume":"166","author":"Modic","year":"1988","journal-title":"Radiology"},{"key":"R19-15-20241212","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.1097\/BRS.0b013e318145a3a9","article-title":"Prevalence of lumbar facet arthrosis and its relationship to age, sex, and race: An anatomic study of cadaveric specimens","volume":"32","author":"Eubanks","year":"2007","journal-title":"Spine (Phila Pa 1976"},{"key":"R20-15-20241212","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.clinthera.2007.01.013","article-title":"Pregabalin: A novel gamma-aminobutyric acid analogue in the treatment of neuropathic pain, partial-onset seizures, and anxiety disorders","volume":"29","author":"Tassone","year":"2007","journal-title":"Clin Ther"},{"key":"R21-15-20241212","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1097\/01.brs.0000261561.12944.ff","article-title":"Modic changes in endplates of lumbar vertebral bodies: Prevalence and association with low back and sciatic pain among middle-aged male workers","volume":"32","author":"Kuisma","year":"2007","journal-title":"Spine (Phila Pa 1976"},{"key":"R22-15-20241212","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1007\/s00330-004-2314-4","article-title":"Longitudinal study of vertebral type-1 end-plate changes on MR of the lumbar spine","volume":"14","author":"Mitra","year":"2004","journal-title":"Eur Radiol"},{"key":"R23-15-20241212","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1007\/s00256-013-1700-x","article-title":"Do more MRI findings imply worse disability or more intense low back pain? A cross-sectional study of candidates for lumbar disc prosthesis","volume":"42","author":"Berg","year":"2013","journal-title":"Skeletal Radiol"},{"key":"R24-15-20241212","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.2106\/00004623-200109000-00002","article-title":"The value of magnetic resonance imaging of the lumbar spine to predict low-back pain in asymptomatic subjects: A seven-year follow-up study","volume":"83-A","author":"Borenstein","year":"2001","journal-title":"J Bone Joint Surg Am"},{"key":"R25-15-20241212","first-page":"1253","article-title":"Relationship between severity of lumbar disc disease and disability scores in sciatica patients","volume":"50","author":"Porchet","year":"2002","journal-title":"Neurosurgery"},{"key":"R26-15-20241212","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.spinee.2013.06.078","article-title":"Quantitative estimation of the high-intensity zone in the lumbar spine: Comparison between the symptomatic and asymptomatic population","volume":"14","author":"Liu","year":"2014","journal-title":"Spine J"},{"key":"R27-15-20241212","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1136\/oemed-2012-101116","article-title":"Work-related psychosocial and mechanical risk factors for low back pain: A 3-year follow-up study of the general working population in Norway","volume":"70","author":"Sterud","year":"2013","journal-title":"Occup Environ Med"},{"key":"R28-15-20241212","first-page":"21","article-title":"Association between strenuous occupational activity and low back pain","volume":"26","author":"Ordo\u00f1ez-Hinojos","year":"2012","journal-title":"Acta Ortop Mex"},{"key":"R29-15-20241212","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1111\/j.1365-2265.2008.03360.x","article-title":"Vitamin D deficiency in rural girls and pregnant women despite abundant sunshine in northern India","volume":"70","author":"Sahu","year":"2009","journal-title":"Clin Endocrinol (Oxf"},{"key":"R30-15-20241212","doi-asserted-by":"crossref","first-page":"76","DOI":"10.2340\/16501977-1070","article-title":"Low back pain associated with sociodemographic factors, lifestyle and osteoporosis: A population-based study","volume":"45","author":"Chou","year":"2013","journal-title":"J Rehabil Med"}],"container-title":["Indian Journal of Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/02223309-201745060-00015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T22:58:59Z","timestamp":1751497139000},"score":1,"resource":{"primary":{"URL":"https:\/\/ijmr.org.in\/clinical-significance-of-magnetic-resonance-imaging-findings-in-chronic-low-backache\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.4103\/ijmr.ijmr_1653_14","relation":{},"ISSN":["0971-5916"],"issn-type":[{"value":"0971-5916","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]}}}