{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T19:16:44Z","timestamp":1790191004141,"version":"4.1.0"},"reference-count":13,"publisher":"Scientific Scholar","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,1]]},"abstract":"\n Background & objectives:<\/jats:title>\n \n Multidrug-resistant Salmonellae have emerged worldwide as also in India. The aim of this study was to study the antimicrobial susceptibility pattern of\n Salmonella enterica<\/jats:italic>\n serovars isolated at a tertiary care hospital in northern India.\n <\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n A total of 106\n S. enterica<\/jats:italic>\n serovars isolated from various clinical samples from January 2011 to June 2012 were tested for antimicrobial susceptibility by Kirby-Bauer disk diffusion method. The minimum inhibitory concentration (MIC) of ciprofloxacin, chloramphenicol and ceftriaxone was determined both by agar dilution method and\n E<\/jats:italic>\n -test for all the isolates.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Salmonella<\/jats:italic>\n Typhi (73.6%) was the predominant isolate followed by\n S.<\/jats:italic>\n Paratyphi A (15.1%),\n S.<\/jats:italic>\n Typhimurium (9.4%) and\n S.<\/jats:italic>\n Enteritidis (1.9%). Of these, 34 (32.1%) were resistant to ciprofloxacin (MIC \u22651 \u03bcg\/ml by agar dilution) with MIC\n 90<\/jats:sub>\n of ciprofloxacin for\n S.<\/jats:italic>\n Typhi,\n S.<\/jats:italic>\n Paratyphi A and\n S.<\/jats:italic>\n Typhimurium being 32, 4 and 1 \u03bcg\/ml, respectively. All the isolates were sensitive to chloramphenicol (MIC \u22648 \u03bcg\/ml) and ceftriaxone (MIC \u22641 \u03bcg\/ml). Disk diffusion method showed high susceptibility rates to cefotaxime (100%), azithromycin (93.4%) and co-trimoxazole (97.2%). Nalidixic acid resistance was seen in 105 (99.1%) isolates. Of the nalidixic acid-resistant strains, only 34 (32.3%) were found to be resistant to ciprofloxacin (MIC \u22651 \u03bcg\/ml).\n <\/jats:p>\n <\/jats:sec>\n \n Interpretation & conclusions:<\/jats:title>\n This study showed an alarming increase in MIC to quinolones and re-emergence of susceptibility to conventional antibiotics among Salmonellae.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijmr.ijmr_862_14","type":"journal-article","created":{"date-parts":[[2017,5,29]],"date-time":"2017-05-29T08:31:30Z","timestamp":1496046690000},"page":"124-128","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":11,"title":["Patterns in antimicrobial susceptibility of Salmonellae isolated at a tertiary care hospital in northern India"],"prefix":"10.25259","volume":"145","author":[{"given":"Preeti","family":"Behl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varsha","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atul","family":"Sachdev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal","family":"Guglani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jagdish","family":"Chander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","reference":[{"key":"R1-19-20241212","doi-asserted-by":"crossref","first-page":"223","DOI":"10.4103\/0255-0857.83904","article-title":"Antimicrobial resistance in typhoidal Salmonellae","volume":"29","author":"Harish","year":"2011","journal-title":"Indian J Med Microbiol"},{"key":"R2-19-20241212","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0255-0857(21)02470-1","article-title":"Changing trends in the antibiograms of Salmonella isolates at a tertiary care hospital in Hyderabad","volume":"24","author":"Lakshmi","year":"2006","journal-title":"Indian J Med Microbiol"},{"key":"R3-19-20241212","doi-asserted-by":"crossref","first-page":"31","DOI":"10.4103\/0255-0857.124292","article-title":"Plasmid-mediated quinolone resistance in typhoidal salmonellae: A preliminary report from South India","volume":"32","author":"Geetha","year":"2014","journal-title":"Indian J Med Microbiol"},{"key":"R6-19-20241212","doi-asserted-by":"crossref","first-page":"633","DOI":"10.3855\/jidc.557","article-title":"Neonatal sepsis due to Salmonella Typhi and Paratyphi A","volume":"3","author":"Mohanty","year":"2009","journal-title":"J Infect Dev Ctries"},{"key":"R7-19-20241212","first-page":"101","article-title":"Treatment of enteric fever in children on the basis of current trends of antimicrobial susceptibility of Salmonella enterica serovar Typhi and Paratyphi A","volume":"24","author":"Manchanda","year":"2006","journal-title":"Indian J Med Microbiol"},{"key":"R8-19-20241212","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1017\/S0950268805005844","article-title":"Antibiogram pattern and seasonality of Salmonella serotypes in a North Indian tertiary care hospital","volume":"134","author":"Mohanty","year":"2006","journal-title":"Epidemiol Infect"},{"key":"R9-19-20241212","doi-asserted-by":"crossref","first-page":"70","DOI":"10.3855\/jidc.109","article-title":"Antimicrobial susceptibility of Salmonella Typhi in India","volume":"4","author":"Nagshetty","year":"2010","journal-title":"J Infect Dev Ctries"},{"key":"R10-19-20241212","first-page":"800","article-title":"Antimicrobial susceptibility of Salmonella enterica serovars in a tertiary care hospital in Southern India","volume":"137","author":"Choudhary","year":"2013","journal-title":"Indian J Med Res"},{"key":"R11-19-20241212","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1099\/jmm.0.47353-0","article-title":"In vitro activity of azithromycin, newer quinolones and cepalosporins in ciprofloxacin resistant Salmonella causing enteric fever","volume":"56","author":"Capoor","year":"2007","journal-title":"J Med Microbiol"},{"key":"R12-19-20241212","first-page":"105","article-title":"Predictive efficacy of nalidixic acid resistance as a marker of fluoroquinolone resistance in Salmonella enterica var Typhi","volume":"124","author":"Ray","year":"2006","journal-title":"Indian J Med Res"},{"key":"R13-19-20241212","doi-asserted-by":"crossref","first-page":"227","DOI":"10.3855\/jidc.1310","article-title":"Re-emergence of susceptibility to conventionally used drugs among strains of Salmonella Typhi in central West India","volume":"5","author":"Kumar","year":"2011","journal-title":"J Infect Dev Ctries"},{"key":"R14-19-20241212","first-page":"92","article-title":"Preserving efficacy of chloramphenicol against typhoid fever in a tertiary care hospital, India","volume":"15","author":"Harish","year":"2011","journal-title":"Regional Health Forum"},{"key":"R15-19-20241212","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1099\/jmm.0.068486-0","article-title":"Detection of TEM-, SHV- and CTX-M-type \u00df-lactamase production among clinical isolates of Salmonella species","volume":"63","author":"Elumalai","year":"2014","journal-title":"J Med Microbiol"}],"container-title":["Indian Journal of Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/02223309-201745010-00019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T19:01:56Z","timestamp":1751482916000},"score":1,"resource":{"primary":{"URL":"https:\/\/ijmr.org.in\/patterns-in-antimicrobial-susceptibility-of-salmonellae-isolated-at-a-tertiary-care-hospital-in-northern-india\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.4103\/ijmr.ijmr_862_14","relation":{},"ISSN":["0971-5916"],"issn-type":[{"value":"0971-5916","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]}}}