{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:29:31Z","timestamp":1787030971082,"version":"build-2736575974"},"reference-count":24,"publisher":"Scientific Scholar","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,2]]},"abstract":"\n Background & objectives:<\/jats:title>\n Guillain\u2013Barre syndrome (GBS) is an autoimmune disease and a recognized cause of generalized progressive paralysis worldwide. The present study was aimed to document the clinical findings, demographics and seasonal variations amongst the patients with GBS during the hospital stay.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n A retrospective analysis of 66 referred cases diagnosed as GBS was conducted. Medical records and the data related to age, sex, antecedent illness, duration of symptoms before admission, muscle power graded by the Medical Research Council scale, functional scores, details of Intensive Care Unit complications and need for ventilation were obtained. The patients were divided into four seasonal groups: S1 (spring, February to April), S2 (summer, May to July), S3 (rainy, August to October) and S4 (winter, November to January) and parameters were studied.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n The mean age of the patients was 40.69 yr. Forty one (62.1%) patients had a history of preceding illness. Forty nine (74.2%) patients showed quadriparesis as most common complaint. Thirty three (50%) patients were of acute inflammatory demyelinating polyneuropathy (AIDP) variant. The highest number of GBS cases (60%) was found in S1 and S2. The maximum duration of hospital stay was observed in S3 group (mean 23 days).<\/jats:p>\n <\/jats:sec>\n \n Interpretation & conclusions:<\/jats:title>\n GBS seems to affect all age groups with male preponderance. Most common antecedent event and presenting feature were flu-like illness and quadriparesis, respectively. AIDP was the most common variant. Most cases occurred from February to July (S1 and S2 group) (maximum in July) with preceding influenza and diarrhoea and maximum duration of hospital stay was observed in S3 group. Prospective studies with follow up of GBS patients need to be done to confirm findings.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijmr.ijmr_995_14","type":"journal-article","created":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T13:54:46Z","timestamp":1734616486000},"page":"203-208","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":18,"title":["Guillain\u2013Barre syndrome"],"prefix":"10.25259","volume":"145","author":[{"given":"Manisha","family":"Shrivastava","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shah","family":"Nehal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navaid","family":"Seema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","reference":[{"key":"R3-9-20241212","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1055\/s-2008-1062261","article-title":"Guillain-Barr\u00e9 syndrome","volume":"28","author":"Burns","year":"2008","journal-title":"Semin Neurol"},{"key":"R4-9-20241212","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/S1474-4422(08)70215-1","article-title":"Clinical features, pathogenesis, and treatment of Guillain-Barr\u00e9 syndrome","volume":"7","author":"van Doorn","year":"2008","journal-title":"Lancet Neurol"},{"key":"R5-9-20241212","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1056\/NEJM199511233332102","article-title":"Campylobacter jejuni infection and Guillain-Barr\u00e9 syndrome","volume":"333","author":"Rees","year":"1995","journal-title":"N Engl J Med"},{"key":"R6-9-20241212","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/jns5.12050","article-title":"Guillain-Barr\u00e9 syndrome: Subtypes and predictors of outcome from India","volume":"19","author":"Kalita","year":"2014","journal-title":"J Peripher Nerv Syst"},{"key":"R7-9-20241212","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1086\/594124","article-title":"Guillain-Barr\u00e9 syndrome and influenza virus infection","volume":"48","author":"Sivadon-Tardy","year":"2009","journal-title":"Clin Infect Dis"},{"key":"R8-9-20241212","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.1600-0404.1985.tb03165.x","article-title":"Epidemiology of the Guillain-Barr\u00e9 syndrome in the county of Hordaland, Western Norway","volume":"71","author":"Larsen","year":"1985","journal-title":"Acta Neurol Scand"},{"key":"R9-9-20241212","first-page":"6","article-title":"Seasonal variation and sex distribution in patients with Guillain-Barr\u00e9 syndrome","volume":"3","author":"Zaheer","year":"2008","journal-title":"Pak J Neurol Sci"},{"key":"R10-9-20241212","doi-asserted-by":"crossref","first-page":"23","DOI":"10.4236\/nm.2013.41004","article-title":"Seasonal, age & gender variation of Guillain Barre syndrome in a tertiary referral center in India","volume":"4","author":"Sharma","year":"2013","journal-title":"Neurosci Med"},{"key":"R11-9-20241212","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1093\/brain\/awm004","article-title":"Immunotherapy for Guillain-Barr\u00e9 syndrome: A systematic review","volume":"130","author":"Hughes","year":"2007","journal-title":"Brain"},{"key":"R12-9-20241212","first-page":"CD001798","article-title":"Plasma exchange for Guillain-Barr\u00e9 syndrome","volume":"7","author":"Rapha\u00ebl","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"R13-9-20241212","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1001\/archneur.62.8.1194","article-title":"Supportive care for patients with Guillain-Barr\u00e9 syndrome","volume":"62","author":"Hughes","year":"2005","journal-title":"Arch Neurol"},{"key":"R15-9-20241212","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/S0140-6736(78)92644-2","article-title":"Controlled trial prednisolone in acute polyneuropathy","volume":"ii","author":"Hughes","year":"1978","journal-title":"Lancet"},{"key":"R16-9-20241212","doi-asserted-by":"crossref","first-page":"349","DOI":"10.4103\/0028-3886.117582","article-title":"Seasonal variation in the clinical recovery of patients with Guillain Barr\u00e9 syndrome requiring mechanical ventilation","volume":"61","author":"Sriganesh","year":"2013","journal-title":"Neurol India"},{"key":"R17-9-20241212","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1159\/000184748","article-title":"The epidemiology of Guillain-Barr\u00e9 syndrome worldwide. 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