{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:26:54Z","timestamp":1787761614675,"version":"build-2784847793"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Mycobacterium tuberculosis<\/jats:italic>\n                      infection (TB) masquerading as lung tumor is well reported, but its mimicry as metastatic thoracic cancer is rare. We report the case of a young male who presented with clinical and radiological picture of lung cancer but investigations confirmed it as TB. A 35-year-old male, with 18-pack year of smoking history, presented with dry cough, anorexia, weight loss, and lower back and left hip pain. Chest imaging showed right upper lobe speculated mass with mediastinal and hilar lymphadenopathy and a lytic lesion in the left sacral area. Magnetic resonance imaging of the spine and pelvis revealed lytic lesion in the left sacrum. Fluorodeoxyglucose positron emission tomography computed tomography scan of the whole body showed hypermetabolic lung lesion with ipsilateral mediastinal, supraclavicular, splenic, and bone metastasis in the left aspect of the sacrum. Computed tomography (CT)-guided biopsy of the lung lesion showed necrotizing granuloma and tissue culture was positive for pan-susceptible\n                      <jats:italic toggle=\"yes\">M. tuberculosis<\/jats:italic>\n                      . Follow-up CT scan showed complete resolution of the lung lesion and lymph nodes after anti-TB treatment with significant reduction in the sacral lesion. Mycobacterial infection may mimic metastatic lung cancer and should always be considered a differential diagnosis.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijmy.ijmy_89_21","type":"journal-article","created":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T08:57:49Z","timestamp":1682067469000},"page":"327-329","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":14,"title":["Tuberculosis Presenting as Metastatic Lung Cancer"],"prefix":"10.4103","volume":"10","author":[{"given":"Sarfraz A","family":"Saleemi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bader","family":"Alothman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Alamer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sultan","family":"Alsayari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulaziz","family":"Almogbel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shamayel","family":"Mohammed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-17-20240902","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ijid.2017.03.024","article-title":"Prevalence of Latent Mycobacterium tuberculosis Infection (LTBI) in Saudi Arabia; Population based survey","volume":"60","author":"Balkhy","year":"2017","journal-title":"Int J Infect Dis"},{"key":"R3-17-20240902","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S1473-3099(05)70163-8","article-title":"Miliary tuberculosis: New insights into an old disease","volume":"5","author":"Sharma","year":"2005","journal-title":"Lancet Infect Dis"},{"key":"R4-17-20240902","doi-asserted-by":"crossref","first-page":"418","DOI":"10.3945\/an.116.012211","article-title":"World Cancer Report 2014. Geneva, Switzerland: World Health Organization, International Agency for Research on Cancer, WHO Press, 2015","volume":"7","author":"McGuire","year":"2016","journal-title":"Adv Nutr"},{"key":"R5-17-20240902","first-page":"239","article-title":"A follow-up examination of patients with pulmonary tuberculosis resected on suspicion of tumour","volume":"57","author":"Prytz","year":"1976","journal-title":"Scand J Respir Dis"},{"key":"R6-17-20240902","first-page":"1103","article-title":"Tuberculosis presenting as endobronchial tumor","volume":"25","author":"Saleemi","year":"2004","journal-title":"Saudi Med J"},{"key":"R7-17-20240902","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0720-048X(01)00402-8","article-title":"Bilateral multiple pulmonary tuberculous nodules mimicking metastatic disease","volume":"44","author":"Ariy\u00fcrek","year":"2002","journal-title":"Eur J Radiol"},{"key":"R8-17-20240902","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1136\/bcr.11.2010.3539","article-title":"Bilateral nodular pulmonary tuberculomas simulating metastatic disease","volume":"2011","author":"Kant","year":"2011","journal-title":"BMJ Case Rep"},{"key":"R9-17-20240902","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/cid\/ciw778","article-title":"Official American Thoracic Society\/Infectious Diseases Society of America\/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of tuberculosis in adults and children","volume":"64","author":"Lewinsohn","year":"2017","journal-title":"Clin Infect Dis"},{"key":"R10-17-20240902","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1093\/cid\/ciw566","article-title":"Executive Summary: Official American Thoracic Society\/Centers for Disease Control and Prevention\/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of drug-susceptible tuberculosis","volume":"63","author":"Nahid","year":"2016","journal-title":"Clin Infect Dis"},{"key":"R11-17-20240902","first-page":"335","article-title":"A common medical error: Lung cancer misdiagnosed as sputum negative tuberculosis","volume":"10","author":"Singh","year":"2009","journal-title":"Asian Pac J Cancer Prev"},{"key":"R12-17-20240902","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1097\/SMJ.0b013e318218700a","article-title":"Multimodality FDG PET\/CT appearance of pulmonary tuberculoma mimicking lung cancer and pathologic correlation in a tuberculosis-endemic country","volume":"104","author":"Zheng","year":"2011","journal-title":"South Med J"},{"key":"R13-17-20240902","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.ijmyco.2015.07.001","article-title":"A case of tuberculosis and adenocarcinoma coexisting in the same lung lobe","volume":"5","author":"Rihawi","year":"2016","journal-title":"Int J Mycobacteriol"},{"key":"R14-17-20240902","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1136\/jclinpath-2016-203868","article-title":"Significance of coexistent granulomatous inflammation and lung cancer","volume":"70","author":"Dagaonkar","year":"2017","journal-title":"J Clin Pathol"},{"key":"R15-17-20240902","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.ijmyco.2015.05.015","article-title":"Reactivation of pulmonary tuberculosis during cancer treatment","volume":"4","author":"Jacobs","year":"2015","journal-title":"Int J Mycobacteriol"}],"container-title":["The International Journal of Mycobacteriology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijmy.ijmy_89_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:01:44Z","timestamp":1787760104000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijmy.ijmy_89_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijmy.ijmy_89_21","relation":{},"ISSN":["2212-5531"],"issn-type":[{"value":"2212-5531","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}