{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T22:44:24Z","timestamp":1779317064071,"version":"3.51.4"},"reference-count":15,"publisher":"Scientific Scholar","content-domain":{"domain":["indianjnephrol.org"],"crossmark-restriction":true},"short-container-title":["IJN"],"abstract":"<jats:p>Salicylates are often used in clinical practice as antiplatelets as well as analgesics. Its overdose is not uncommon due to its easy availability over the counter. Mortality is high in severe cases when a lethal dose is consumed. Treatment of overdose is difficult due to the non-availability of an antidote. Hemodialysis is an underutilized treatment modality in such cases. We discuss here a case of a young female who presented to us 2.5 h after the consumption of a lethal dose of salicylate with symptoms of only tinnitus. She was successfully treated with two sessions of hemodialysis. Her drug levels on admission were remarkably high, and early hemodialysis was justified in view of high-dose consumption with minimal symptoms.<\/jats:p>","DOI":"10.4103\/ijn.ijn_141_22","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T09:12:52Z","timestamp":1711703572000},"page":"67-69","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Timely Hemodialysis for Successful Treatment of Acute Salicylate Overdose in a Young Adult Female \u2013 A Case Report"],"prefix":"10.25259","volume":"34","author":[{"given":"Amitabh","family":"Kulkarni","sequence":"first","affiliation":[{"name":"Department of Nephrology, NMC Specialty Hospital, Dubai, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavan","family":"Shrivastava","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, NMC Specialty Hospital, Dubai, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh Kumar","family":"Phulara","sequence":"additional","affiliation":[{"name":"Department of Critical Care Unit, NMC Specialty Hospital, Dubai, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2023,2,21]]},"reference":[{"key":"10.4103\/ijn.ijn_141_22\/ref-1","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.annemergmed.2015.03.031","article-title":"Extracorporeal treatment for salicylate poisoning: Systematic review and recommendations from the EXTRIP workgroup","volume":"66","author":"Juurlink","year":"2015","journal-title":"Ann Emerg Med"},{"key":"10.4103\/ijn.ijn_141_22\/ref-2","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1111\/j.1399-6576.1987.tb02574.x","article-title":"Acute salicylate self-poisoning in 177 consecutive patients treated in ICU","volume":"31","author":"Thisted","year":"1987","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.4103\/ijn.ijn_141_22\/ref-3","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1001\/archinte.1987.00370030114022","article-title":"A two-year review of salicylate deaths in Ontario","volume":"147","author":"Mcguigan","year":"1987","journal-title":"Arch Intern Med"},{"key":"10.4103\/ijn.ijn_141_22\/ref-4","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1080\/10408444.2016.1236071","article-title":"A critical review of the literature to conduct a toxicity assessment for oral exposure to methyl salicylate","volume":"47","author":"Greene","year":"2017","journal-title":"Crit Rev Toxicol"},{"key":"10.4103\/ijn.ijn_141_22\/ref-5","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1016\/j.jaad.2013.12.005","article-title":"A review of toxicity from topical salicylic acid preparations","volume":"70","author":"Madan","year":"2014","journal-title":"J Am Acad Dermatol"},{"key":"10.4103\/ijn.ijn_141_22\/ref-6","doi-asserted-by":"publisher","first-page":"1697","DOI":"10.1002\/ccr3.2346","article-title":"Intentional acetylsalicylic acid acute intoxication and its clinical management","volume":"7","author":"Soleimani","year":"2019","journal-title":"Clin Case Rep"},{"key":"10.4103\/ijn.ijn_141_22\/ref-7","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1345\/aph.1D575","article-title":"Delayed salicylate toxicity at 35 hours without early manifestations following a single salicylate ingestion","volume":"38","author":"Rivera","year":"2004","journal-title":"Ann Pharmacother"},{"key":"10.4103\/ijn.ijn_141_22\/ref-8","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1177\/102490791001700314","article-title":"Case report of aspirin overdose: Bezoar formation and controversies of multiple-dose activated charcoal in salicylate poisoning","volume":"17","author":"Wong","year":"2010","journal-title":"Hong Kong J Emerg Med"},{"key":"10.4103\/ijn.ijn_141_22\/ref-9","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1097\/00007611-199605000-00005","article-title":"Systemic inflammatory response syndrome caused by chronic salicylate intoxication","volume":"89","author":"Chalasani","year":"1996","journal-title":"South Med J"},{"key":"10.4103\/ijn.ijn_141_22\/ref-10","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1056\/NEJM197305242882107","article-title":"Salicylate intoxication","volume":"288","author":"Hill","year":"1973","journal-title":"N Engl J Med"},{"key":"10.4103\/ijn.ijn_141_22\/ref-11","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1542\/peds.23.2.260","article-title":"Disturbances of acid-base equilibrium in salicylate intoxication","volume":"23","author":"Winters","year":"1959","journal-title":"Pediatrics"},{"key":"10.4103\/ijn.ijn_141_22\/ref-12","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.1001\/archinte.1978.03630350019008","article-title":"Acid-base disturbances in the salicylate-intoxicated adult","volume":"138","author":"Gabon","year":"1978","journal-title":"Arch Intern Med"},{"key":"10.4103\/ijn.ijn_141_22\/ref-13","doi-asserted-by":"publisher","first-page":"e920016","DOI":"10.12659\/AJCR.920016","article-title":"A case of salicylate toxicity presenting with acute focal neurologic deficit in a 61-year-old woman with a history of stroke","volume":"21","author":"Tessa","year":"2020","journal-title":"Am J Case Rep"},{"key":"10.4103\/ijn.ijn_141_22\/ref-14","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.annemergmed.2011.02.023","article-title":"Falsely normal anion gap in severe salicylate poisoning caused by laboratory interference","volume":"58","author":"Jacob","year":"2011","journal-title":"Ann Emerg Med"},{"key":"10.4103\/ijn.ijn_141_22\/ref-15","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1038\/ki.2008.443","article-title":"The underutilization of hemodialysis in patients with salicylate poisoning","volume":"75","author":"Fertel","year":"2009","journal-title":"Kidney Int"}],"container-title":["Indian Journal of Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/indianjnephrol.org\/timely-hemodialysis-for-successful-treatment-of-acute-salicylate-overdose-in-a-young-adult-female-a-case-report\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/indianjnephrol.org\/timely-hemodialysis-for-successful-treatment-of-acute-salicylate-overdose-in-a-young-adult-female-a-case-report\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T05:01:37Z","timestamp":1712206897000},"score":1,"resource":{"primary":{"URL":"https:\/\/indianjnephrol.org\/timely-hemodialysis-for-successful-treatment-of-acute-salicylate-overdose-in-a-young-adult-female-a-case-report\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,21]]},"references-count":15,"alternative-id":["10.4103\/ijn.ijn_141_22"],"URL":"https:\/\/doi.org\/10.4103\/ijn.ijn_141_22","relation":{},"ISSN":["1998-3662","0971-4065"],"issn-type":[{"value":"1998-3662","type":"electronic"},{"value":"0971-4065","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2,21]]},"article-number":"67"}}