{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T00:44:09Z","timestamp":1712277849992},"reference-count":14,"publisher":"Scientific Scholar","content-domain":{"domain":["indianjnephrol.org"],"crossmark-restriction":true},"short-container-title":["IJN"],"abstract":"<jats:p>Proliferative glomerulonephritis in myelofibrosis is a very rare. Mesangial proliferation and sclerosis with changes of chronic thrombotic microangiopathy have been reported, but pauci-immune focal crescentic glomerulonephritis has not been described so far. Herein, we present a 68-year-old male who was a known case of myelofibrosis and presented with rapidly progressive glomerulonephritis and nephrotic range proteinuria. He was diagnosed as anti-neutrophil cytoplasmic antibody (ANCA)-negative focal crescentic glomerulonephritis, and he responded well to a course of intravenous methylprednisolone and cyclophosphamide. Pauci-immune focal crescentic glomerulonephritis may occur in myelofibrosis without ANCA and may be related to unknown pathogenetic mechanisms in myeloproliferative disorders or suggest any superimposed pathology that might respond well to immunosuppressants.<\/jats:p>","DOI":"10.4103\/ijn.ijn_218_22","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T09:12:52Z","timestamp":1711703572000},"page":"64-66","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Focal Crescentic Glomerulonephritis Superimposed on Myeloproliferative Disease-Related Glomerulopathy in a Case of Myelofibrosis"],"prefix":"10.25259","volume":"34","author":[{"given":"Janmejay Ashvinkumar","family":"Kunpara","sequence":"first","affiliation":[{"name":"Department of Nephrology, Zydus Hospitals, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhavya Prakash","family":"Darji","sequence":"additional","affiliation":[{"name":"GCS Medical College, Ahmedabad, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Himanshu Arvindbhai","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Zydus Hospitals, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devang","family":"Patwari","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Zydus Hospitals, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sujit Shaileshbhai","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Zydus Hospitals, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prakash Ishwarlal","family":"Darji","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Zydus Hospitals, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2023,2,21]]},"reference":[{"key":"10.4103\/ijn.ijn_218_22\/ref-1","doi-asserted-by":"publisher","first-page":"160","DOI":"10.3389\/fmed.2018.00160","article-title":"Physiology of hyperuricemia and urate-lowering treatments","volume":"5","author":"Benn","year":"2018","journal-title":"Front Med (Lausanne)"},{"key":"10.4103\/ijn.ijn_218_22\/ref-2","doi-asserted-by":"publisher","first-page":"1292","DOI":"10.1016\/j.kint.2017.06.009","article-title":"Acute renal infarction: A presentation of essential thrombocytosis","volume":"92","author":"\u00d6zpolat","year":"2017","journal-title":"Kidney Int"},{"key":"10.4103\/ijn.ijn_218_22\/ref-3","doi-asserted-by":"publisher","first-page":"1729","DOI":"10.1182\/bloodadvances.2019000211","article-title":"Leukocytosis and thrombosis in essential thrombocythemia and polycythemia vera: A systematic review and meta-analysis","volume":"3","author":"Carobbio","year":"2019","journal-title":"Blood Adv"},{"key":"10.4103\/ijn.ijn_218_22\/ref-4","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1016\/S0272-6386(99)70047-8","article-title":"Focal segmental glomerulosclerosis and mesangial sclerosis associated with myeloproliferative disorders","volume":"34","author":"Au","year":"1999","journal-title":"Am J Kidney Dis"},{"key":"10.4103\/ijn.ijn_218_22\/ref-5","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1038\/ki.2011.147","article-title":"Myeloproliferative neoplasms cause glomerulopathy","volume":"80","author":"Said","year":"2011","journal-title":"Kidney Int"},{"key":"10.4103\/ijn.ijn_218_22\/ref-6","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1111\/his.14282","article-title":"Renal disease associated with myeloproliferative neoplasms and myelodysplastic syndrome\/myeloproliferative neoplasms","volume":"78","author":"B\u00fcttner-Herold","year":"2021","journal-title":"Histopathology"},{"key":"10.4103\/ijn.ijn_218_22\/ref-7","doi-asserted-by":"publisher","first-page":"2452","DOI":"10.1056\/NEJMra063728","article-title":"The myeloproliferative disorders","volume":"355","author":"Campbell","year":"2006","journal-title":"N Engl J Med"},{"key":"10.4103\/ijn.ijn_218_22\/ref-8","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1038\/sj.leu.2404955","article-title":"Classification and diagnosis of myeloproliferative neoplasms. 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