{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T23:09:17Z","timestamp":1779318557742,"version":"3.51.4"},"reference-count":15,"publisher":"Scientific Scholar","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Hydroxychloroquine (HCQ) has immunomodulatory and immunosuppressive properties and is used in many rheumatological conditions like systemic lupus erythematosus, rheumatoid arthritis, and Sjogren\u2019s syndrome. It is usually a widely used and well-tolerated DMARD (Disease Modifying Anti Rheumatic Drugs). Its most feared toxicities include retinopathy and, rarely, cardiomyopathy. Among its other reported side effects is drug-induced phospholipidosis. Here, we report two cases of HCQ-induced phospholipidosis based on renal biopsy electron microscopy. HCQ-induced phospholipidosis, although uncommon, must be considered as one of the differentials in a patient with persistent proteinuria.<\/jats:p>","DOI":"10.4103\/ijn.ijn_325_22","type":"journal-article","created":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T11:00:43Z","timestamp":1691406043000},"source":"Crossref","is-referenced-by-count":1,"title":["Hydroxychloroquine-Induced Phospholipidosis \u2013 A Forgotten Complication of a Common Drug"],"prefix":"10.25259","author":[{"given":"Nagamounika","family":"Kothapalli","sequence":"first","affiliation":[{"name":"Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shivraj","family":"Padiyar","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aswin M.","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Travancore Medical College Hospital, Kollam, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prathyusha","family":"Manikuppam","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Smitha M.","family":"Matthai","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeet","family":"Roy","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, 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