{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T08:29:39Z","timestamp":1782289779019,"version":"3.54.5"},"reference-count":22,"publisher":"Scientific Scholar","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Radioactive iodine (RAI) therapy is widely used and has an important role in the management of hyperthyroidism and thyroid malignancies. The development of acute or chronic leukemia is a very rare complication of RAI therapy. We report a case of metastatic Follicular thyroid cancer (FTC) who underwent total thyroidectomy followed by treatment with a cumulative dose of 1600 mCi of RAI (for 4 years) and by palliative radiotherapy for L4 spinal metastasis, later on, developed acute myeloid leukemia. Thus, all patients with thyroid carcinoma treated with RAI should undergo periodic hematological examinations irrespective of RAI dose.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijnm.ijnm_133_22","type":"journal-article","created":{"date-parts":[[2023,2,23]],"date-time":"2023-02-23T12:34:14Z","timestamp":1677155654000},"page":"56-58","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Acute Myeloid Leukemia following Radioactive Iodine Therapy for Metastatic Follicular Carcinoma of the Thyroid"],"prefix":"10.25259","volume":"38","author":[{"given":"Komal","family":"Bishnoi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph","family":"Emerson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Girish Kumar","family":"Parida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prapti","family":"Acharya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somanath","family":"Padhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanhaiyalal","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","reference":[{"key":"R1-10-20240902","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1259\/0007-1285-28-327-165","article-title":"Acute leukaemia following x-ray and radioiodine treatment of thyroid carcinoma","volume":"28","author":"Blom","year":"1955","journal-title":"Br J Radiol"},{"key":"R2-10-20240902","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1159\/000505686","article-title":"Acute myeloid leukemia after low-dose radioiodine therapy for papillary thyroid carcinoma","volume":"13","author":"Alsaud","year":"2020","journal-title":"Case Rep Oncol"},{"key":"R3-10-20240902","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s10552-015-0682-5","article-title":"Therapy-related acute myeloid leukemia following radioactive iodine treatment for thyroid cancer","volume":"27","author":"Oluwasanjo","year":"2016","journal-title":"Cancer Causes Control"},{"key":"R4-10-20240902","doi-asserted-by":"crossref","first-page":"225","DOI":"10.5045\/kjh.2012.47.3.225","article-title":"A case of therapy-related acute myeloid leukemia with inv(16)(p13.1q22) after single low-dose iodine-131 treatment for thyroid cancer","volume":"47","author":"Jeong","year":"2012","journal-title":"Korean J Hematol"},{"key":"R5-10-20240902","first-page":"767","article-title":"Acute leukemias after treatment with radioiodine for thyroid cancer","volume":"83","author":"Rold\u00e1n Schilling","year":"1998","journal-title":"Haematologica"},{"key":"R6-10-20240902","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1365-2257.1993.tb00121.x","article-title":"Acute promyelocytic leukaemia following radioiodine therapy","volume":"15","author":"Richards","year":"1993","journal-title":"Clin Lab Haematol"},{"key":"R7-10-20240902","first-page":"129","article-title":"Therapy-related acute promyelocytic leukemia after treatment with radioiodine for thyroid cancer: Case report with literature review","volume":"12","author":"Grudeva-Popova","year":"2007","journal-title":"J BUON"},{"key":"R8-10-20240902","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s002770050400","article-title":"Acute myeloid leukemia after iodine-131 treatment for thyroid disorders","volume":"76","author":"Laurenti","year":"1998","journal-title":"Ann Hematol"},{"key":"R9-10-20240902","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1259\/0007-1285-59-697-45","article-title":"The long-term hazards of the treatment of thyroid cancer with radioiodine","volume":"59","author":"Edmonds","year":"1986","journal-title":"Br J Radiol"},{"key":"R10-10-20240902","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/bjc.1973.142","article-title":"Induction of leukemia by 131-I treatment of thyroid carcinoma","volume":"28","author":"Brincker","year":"1973","journal-title":"Br J Cancer"},{"key":"R11-10-20240902","first-page":"1551","article-title":"Intermediate and long-term side effects of high-dose radioiodine therapy for thyroid carcinoma","volume":"39","author":"Alexander","year":"1998","journal-title":"J Nucl Med"},{"key":"R12-10-20240902","first-page":"1496","article-title":"\u201cHigh-dose\u201d radioiodine therapy in advanced differentiated thyroid carcinoma","volume":"37","author":"Menzel","year":"1996","journal-title":"J Nucl Med"},{"key":"R13-10-20240902","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0165-4608(91)90080-E","article-title":"Chronic myelogenous leukemia after treatment with 131-I for thyroid carcinoma. 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