{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T08:05:01Z","timestamp":1779696301713,"version":"3.53.1"},"reference-count":8,"publisher":"Scientific Scholar","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      Osteogenic sarcoma is an aggressive malignant bone tumor arising from primitive mesenchymal bone-forming cells. Ossification is the characteristic feature of the metastases in osteosarcoma which aids their detection on\n                      <jats:sup>99m<\/jats:sup>\n                      Tc-MDP bone scintigraphy. Although lung is the most common site of metastasis in osteogenic sarcoma, pleural involvement with effusion and skip metastases are rare. Herein, we report a case of osteogenic sarcoma of distal femur with diffuse calcified pleural thickening leading to malignant pleural effusion, calcified lung, lymph node, and bone metastases illustrated on bone scan.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijnm.ijnm_177_20","type":"journal-article","created":{"date-parts":[[2021,3,4]],"date-time":"2021-03-04T04:31:38Z","timestamp":1614832298000},"page":"78-79","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Osteogenic Sarcoma Presenting with Skip, Lymph Nodal, Pulmonary, Pleural Metastases and Malignant Effusion"],"prefix":"10.25259","volume":"36","author":[{"given":"Neeraja","family":"Bollampally","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkata Subramanian","family":"Krishnaraju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwani","family":"Sood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameer","family":"Aggarwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhagwant Rai","family":"Mittal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","reference":[{"key":"R1-19-20240902","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s40744-016-0046-y","article-title":"Review of osteosarcoma and current management","volume":"3","author":"Durfee","year":"2016","journal-title":"Rheumatol Ther"},{"key":"R2-19-20240902","doi-asserted-by":"crossref","first-page":"e87","DOI":"10.1016\/j.athoracsur.2017.09.010","article-title":"Pleural metastasis of osteosarcoma","volume":"105","author":"Marchiori","year":"2018","journal-title":"Ann Thorac Surg"},{"key":"R3-19-20240902","first-page":"314","article-title":"Osteosarcoma presenting with malignant pleural effusion in a 55 year old","volume":"25","author":"Krishnamurthy","year":"2018","journal-title":"Respir Med Case Rep"},{"key":"R4-19-20240902","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1007\/s00247-007-0735-3","article-title":"Unusual thoracic CT manifestations of osteosarcoma: Review of 16 cases","volume":"38","author":"Rastogi","year":"2008","journal-title":"Pediatr Radiol"},{"key":"R5-19-20240902","first-page":"129","article-title":"Kissing pleural metastases from metastatic osteosarcoma of the lung","volume":"12","author":"Mori","year":"2006","journal-title":"Ann Thorac Cardiovasc Surg"},{"key":"R6-19-20240902","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1148\/rg.281075015","article-title":"Best cases from the AFIP: Osteosarcoma of the femur with skip, lymph node, and lung metastases","volume":"28","author":"Zwaga","year":"2008","journal-title":"Radiographics"},{"key":"R7-19-20240902","doi-asserted-by":"crossref","first-page":"185","DOI":"10.4103\/0972-3919.136591","article-title":"Synchronous multifocal osteogenic sarcoma on multimodality imaging including bone scintigraphy","volume":"29","author":"Gupta","year":"2014","journal-title":"Indian J Nucl Med"},{"key":"R8-19-20240902","doi-asserted-by":"crossref","first-page":"655","DOI":"10.4103\/0973-1482.106594","article-title":"Extensive 99 m Tc-MDP uptake in metastasis to contralateral pleura from osteosarcoma of femur: An indirect measure of extent of disease involvement at diagnosis","volume":"8","author":"Basu","year":"2012","journal-title":"J Cancer Res Ther"}],"container-title":["Indian Journal of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.4103\/ijnm.IJNM_177_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T07:36:26Z","timestamp":1779694586000},"score":1,"resource":{"primary":{"URL":"https:\/\/ijnm.co.in\/osteogenic-sarcoma-presenting-with-skip-lymph-nodal-pulmonary-pleural-metastases-and-malignant-effusion-an-unusual-appearance-on-bone-scan\/"}},"subtitle":["An Unusual Appearance on Bone Scan"],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijnm.ijnm_177_20","relation":{},"ISSN":["0972-3919"],"issn-type":[{"value":"0972-3919","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}