{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T08:04:48Z","timestamp":1779696288569,"version":"3.53.1"},"reference-count":15,"publisher":"Scientific Scholar","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:p>Silicone implant incompatibility syndrome (SIIS) has been identified as a cause of systemic symptoms such as lymphadenopathy, myalgia, and dyspnea in patients with silicone implants. We present a case of 76-year-old female patient, treated for carcinoma left breast with mastectomy and silicone breast implant, chemotherapy, and radiotherapy 42 years ago. There was a history of implant rupture and removal 2 years ago. The patient presented with right axillary swelling and dyspnea. 18-fluorine fluoro-deoxy-glucose positron emission tomography\/computed tomography (F-18 FDG PET-CT) showed mildly FDG-avid left anterior chest wall and right rectus abdominis deposits, multiple lymph nodes, and low-grade FDG-avid pneumonitis changes in both lungs. Biopsy from the chest wall and rectus abdominis deposit was negative for malignancy and revealed foamy histiocytes and foreign-body giant cell reaction, indicative of SIIS. SIIS is a mimic for metastases and should be considered as a differential diagnosis in FDG PET-CT interpretation in patients with silicone breast implant.<\/jats:p>","DOI":"10.4103\/ijnm.ijnm_29_18","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T08:47:56Z","timestamp":1717058876000},"page":"230-232","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Silicone Implant Incompatibility Syndrome: Mimicking Metastases on Fluoro-Deoxy-Glucose Positron Emission Tomography\u2013Computed Tomography in a Treated Case of Carcinoma Breast"],"prefix":"10.25259","volume":"33","author":[{"given":"Patel","family":"Asra","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine and PET-CT, Apollo Hospitals, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indirani Muthukrishnan","family":"Elangoven","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and PET-CT, Apollo Hospitals, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Shelley","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and PET-CT, Apollo Hospitals, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurian","family":"Ann","sequence":"additional","affiliation":[{"name":"Department of Pathology, Apollo Hospitals, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","reference":[{"key":"R1-20250605","first-page":"534","article-title":"Women with silicone breast implants and unexplained systemic symptoms: A descriptive cohort study","volume":"71","author":"Maijers","year":"2013","journal-title":"Neth J 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