{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:29:31Z","timestamp":1787030971522,"version":"build-2736575974"},"reference-count":13,"publisher":"Scientific Scholar","issue":"6","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:p>\n                    Metastases from squamous cell carcinoma of the lung typically occur in the brain, liver, adrenal glands, bone, and regional lymph nodes. It is exceedingly uncommon to encounter multiple rare sites of metastasis from a single primary neoplasm. Herein, we describe a case of a 44-year-old male diagnosed with squamous cell carcinoma lung with pituitary and renal metastasis detected on\n                    <jats:sup>18<\/jats:sup>\n                    F-FDG (Fluorodeoxyglucose) PET\/CT.\n                    <jats:sup>18<\/jats:sup>\n                    F-FDG PET\/CT is the standard of care and is an integral part of the clinical staging of patients with lung cancer. According to published literature, the incidence of symptomatic pituitary and renal metastasis from squamous cell carcinoma lung is rare to find with incidences &lt;1% and 5%, respectively. The revelation of rare sites of metastasis originating from primary squamous cell carcinoma lung, as reported in this case on FDG PET\/CT, illuminates the exceptional rarity and intricacies in oncology. The exquisite sensitivity of FDG PET\/CT enables the identification of occult metastasis in atypical anatomical locations, presenting a distinct advantage over conventional imaging modalities.\n                  <\/jats:p>","DOI":"10.4103\/ijnm.ijnm_57_24","type":"journal-article","created":{"date-parts":[[2025,3,20]],"date-time":"2025-03-20T13:51:26Z","timestamp":1742478686000},"page":"454-456","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Intriguing Encounter: Unveiling Squamous Cell Carcinoma Lung with Rare Bilateral Renal and Pituitary Metastasis on [18F]-FDG PET\/CT"],"prefix":"10.25259","volume":"39","author":[{"given":"Prakash","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine, King George Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yogita","family":"Khandelwal","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vineet","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, King George Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bela","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2025,3,20]]},"reference":[{"key":"R1-20250320","doi-asserted-by":"crossref","first-page":"E8.","DOI":"10.3171\/foc.2004.16.4.9","article-title":"Metastases to the pituitary gland","volume":"16","author":"Fassett","year":"2004","journal-title":"Neurosurg Focus"},{"key":"R2-20250320","first-page":"e22608.","article-title":"Lung cancer metastasis to the pituitary gland","volume":"14","author":"Kilbane Myers","year":"2022","journal-title":"Cureus"},{"key":"R3-20250320","doi-asserted-by":"crossref","first-page":"S211","DOI":"10.1378\/chest.12-2355","article-title":"Methods for staging non-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines","volume":"143","author":"Silvestri","year":"2013","journal-title":"Chest"},{"key":"R4-20250320","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1158\/1078-0432.CCR-11-2370","article-title":"Squamous cell carcinoma of the lung: Molecular subtypes and therapeutic opportunities","volume":"18","author":"Perez-Moreno","year":"2012","journal-title":"Clin Cancer Res"},{"key":"R5-20250320","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1111\/bju.13194","article-title":"Metastases to the kidney: A comprehensive analysis of 151 patients from a tertiary referral centre","volume":"117","author":"Zhou","year":"2016","journal-title":"BJU Int"},{"key":"R6-20250320","doi-asserted-by":"crossref","first-page":"149.","DOI":"10.1186\/s12885-016-2169-5","article-title":"Distribution and prognosis of uncommon metastases from non-small cell lung cancer","volume":"16","author":"Niu","year":"2016","journal-title":"BMC Cancer"},{"key":"R7-20250320","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1007\/s002619900337","article-title":"Secondary renal neoplasms","volume":"23","author":"Bailey","year":"1998","journal-title":"Abdom Imaging"},{"key":"R8-20250320","doi-asserted-by":"crossref","first-page":"W168","DOI":"10.2214\/AJR.11.7923","article-title":"PET\/CT and renal pathology: A blind spot for radiologists? Part 2 \u2013 Lymphoma, leukemia, and metastatic disease","volume":"199","author":"Zukotynski","year":"2012","journal-title":"Am J Roentgenol"},{"key":"R9-20250320","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1097\/RLU.0000000000000875","article-title":"Preoperative evaluation of renal cell carcinoma by using 18F-FDG PET\/CT","volume":"40","author":"Takahashi","year":"2015","journal-title":"Clin Nucl Med"},{"key":"R10-20250320","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/j.1754-9485.2010.02181.x","article-title":"Role of FDG PET\/CT in imaging of renal lesions","volume":"54","author":"Kochhar","year":"2010","journal-title":"J Med Imaging Radiat Oncol"},{"key":"R11-20250320","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/s11102-013-0542-9","article-title":"Clinical and biochemical characteristic features of metastatic cancer to the sella turcica: An analytical review","volume":"17","author":"Al-Aridi","year":"2014","journal-title":"Pituitary"},{"key":"R12-20250320","doi-asserted-by":"crossref","first-page":"207","DOI":"10.12659\/AJCR.913388","article-title":"Small cell lung cancer with pituitary metastasis presenting as secondary adrenal insufficiency: A case report and literature review","volume":"20","author":"Atallah-Yunes","year":"2019","journal-title":"Am J Case Rep"},{"key":"R13-20250320","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1148\/rg.2018180060","article-title":"Role of FDG PET\/CT in the eighth edition of TNM staging of non-small cell lung cancer","volume":"38","author":"Kandathil","year":"2018","journal-title":"Radiographics"}],"container-title":["Indian Journal of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.4103\/ijnm.ijnm_57_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T07:38:22Z","timestamp":1779694702000},"score":1,"resource":{"primary":{"URL":"https:\/\/ijnm.co.in\/intriguing-encounter-unveiling-squamous-cell-carcinoma-lung-with-rare-bilateral-renal-and-pituitary-metastasis-on-18f-fdg-pet-ct\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ijnm.ijnm_57_24","relation":{},"ISSN":["0972-3919","0974-0244"],"issn-type":[{"value":"0972-3919","type":"print"},{"value":"0974-0244","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"2024-05-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}