{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T08:05:29Z","timestamp":1779696329708,"version":"3.53.1"},"reference-count":9,"publisher":"Scientific Scholar","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"\n \n A 60-year-old male, a diagnosed case of squamous cell carcinoma of the hypopharynx, underwent 18F-fluorodeoxyglucose positron emission tomography\/computed tomography (18F-FDG PET\/CT) for response assessment. PET\/CT revealed mildly increased 18F-FDG uptake and contrast enhancement in the region of the primary, which was suggestive of postradiation changes. Interestingly, a benign-looking cyst was seen in the shrunken, poorly-functioning left kidney, with mildly elevated 18F-FDG uptake. Structurally, the lesion appeared benign on ultrasound and sequential CT images. However, 18F-FDG was the only feature which alluded to the possibility of another pathology like low-grade malignancy or oncocytoma. The lesion was biopsied, which revealed Clear-Cell International Society of Urologic Pathologists grade-1 renal cell carcinoma. 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