{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T18:29:29Z","timestamp":1793730569502,"version":"4.6.1"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>The study assesses the effectiveness and safety of low-dose (3 mg) intraoperative intravitreal triamcinolone acetonide (IVTA) in managing postoperative inflammation and promoting early visual rehabilitation in patients with uveitic cataracts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was a prospective, interventional, and comparative study that included a total of 30 patients with uveitic cataracts, who were divided into two groups. A control group that did not receive the IVTA injection and an IVTA group that received the intravitreal injection at the end of surgery. Results were monitored over 12 months. The evaluated outcomes comprised best corrected visual acuity (BCVA), central macular thickness (CMT), intraocular pressure (IOP), anterior chamber inflammatory response, endothelial cell count (ECC), and any postoperative adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      At 12 months, the IVTA group demonstrated a marked improvement in mean logMAR BCVA from 1.74 \u00b1 0.42 to 0.27 \u00b1 0.17, compared with 0.52 \u00b1 0.19 in controls (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). Anterior chamber inflammation was better controlled in the IVTA group, although the difference was not statistically significant (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05). No significant intergroup differences were noted in IOP or ECC. At 3 months, mean CMT measured 250.42 \u00b1 32.41 \u00b5m in the IVTA group versus 258.25 \u00b1 43.06 \u00b5m in controls (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.494). Postoperative complications were fewer in the IVTA group, with posterior capsule opacification (PCO) being the most frequent.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>About 3 mg triamcinolone acetonide (TA) is not only effective but also safe in reducing postoperative inflammation and promoting early visual recovery in uveitic cataract patients undergoing surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1015_25","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T05:00:15Z","timestamp":1779858015000},"page":"887-892","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Impact of intraoperative 3 mg triamcinolone acetonide injection on visual rehabilitation and inflammation control in uveitic cataract patients undergoing small-incision cataract surgery"],"prefix":"10.4103","volume":"74","author":[{"given":"Mirza M","family":"Beg","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, MLN Medical College, Allahabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apurva","family":"Bagla","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, MLN Medical College, Allahabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jagriti","family":"Rana","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, MLN Medical College, Allahabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santosh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, MLN Medical College, Allahabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aparajita","family":"Chaudhary","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, MLN Medical College, Allahabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinod K","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, MLN Medical College, Allahabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,5,27]]},"reference":[{"key":"R1-20261103","doi-asserted-by":"crossref","first-page":"e7353","DOI":"10.1097\/MD.0000000000007353","article-title":"Efficacy of cataract surgery in patients with uveitis: A STROBE-compliant article","volume":"96","author":"Zhang","year":"2017","journal-title":"Medicine (Baltimore)"},{"key":"R2-20261103","doi-asserted-by":"crossref","first-page":"3923","DOI":"10.4103\/ijo.IJO_1609_22","article-title":"Manual small-incision cataract surgery under topical anesthesia for post-uveitis complicated cataract","volume":"70","author":"Ravindra","year":"2022","journal-title":"Indian J Ophthalmol"},{"key":"R3-20261103","doi-asserted-by":"crossref","first-page":"220","DOI":"10.4103\/ojo.OJO_102_2016","article-title":"Causes and management of small pupil in patients with cataract","volume":"10","author":"Halkiadakis","year":"2017","journal-title":"Oman J Ophthalmol"},{"key":"R4-20261103","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.ophtha.2020.08.035","article-title":"Seven-year outcomes of uveitic macular edema: The multicenter uveitis steroid treatment trial and follow-up study results","volume":"128","author":"Tomkins-Netzer","year":"2021","journal-title":"Ophthalmology"},{"key":"R5-20261103","doi-asserted-by":"crossref","first-page":"430","DOI":"10.3109\/09273948.2015.1025982","article-title":"Intravitreal triamcinolone injection for uveitic macular edema: A randomized clinical study","volume":"23","author":"Shin","year":"2015","journal-title":"Ocul Immunol Inflamm"},{"key":"R6-20261103","doi-asserted-by":"crossref","first-page":"402","DOI":"10.3109\/09273948.2010.486098","article-title":"Intraoperative intravitreal injection of triamcinolone acetonide for cataract extraction in patients with uveitis","volume":"18","author":"Alkawas","year":"2010","journal-title":"Ocul Immunol Inflamm"},{"key":"R7-20261103","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1186\/s12886-021-02017-y","article-title":"Intraoperative intravitreal triamcinolone acetonide injection for prevention of postoperative inflammation and complications after phacoemulsification in patients with uveitic cataract","volume":"21","author":"Ren","year":"2021","journal-title":"BMC Ophthalmol"},{"key":"R8-20261103","first-page":"965","article-title":"Phacoemulsification versus small incision cataract surgery in patients with uveitis","volume":"8","author":"Bhargava","year":"2015","journal-title":"Int J Ophthalmol"},{"key":"R9-20261103","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0161-6420(02)01969-3","article-title":"Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection","volume":"110","author":"Beer","year":"2003","journal-title":"Ophthalmology"},{"key":"R10-20261103","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.ophtha.2018.08.021","article-title":"Periocular triamcinolone vs. intravitreal triamcinolone vs. intravitreal dexamethasone implant for the treatment of uveitic macular edema: The PeriOcular vs. INTravitreal corticosteroids for uveitic macular edema (POINT) trial","volume":"126","author":"Thorne","year":"2019","journal-title":"Ophthalmology"},{"key":"R11-20261103","doi-asserted-by":"crossref","first-page":"3927","DOI":"10.4103\/ijo.IJO_1571_22","article-title":"Long-term outcomes of small-incision cataract surgery in patients with uveitis","volume":"70","author":"Bhargava","year":"2022","journal-title":"Indian J Ophthalmol"},{"key":"R12-20261103","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/eye.2001.197","article-title":"Phacoemulsification with intraocular lens implantation in patients with uveitis","volume":"15","author":"Suresh","year":"2001","journal-title":"Eye (Lond)"},{"key":"R13-20261103","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0002-9394(00)00909-0","article-title":"Phacoemulsification cataract extraction and posterior chamber lens implantation in patients with uveitis","volume":"131","author":"Estafanous","year":"2001","journal-title":"Am J Ophthalmol"},{"key":"R14-20261103","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1046\/j.1440-1606.1999.00238.x","article-title":"Intravitreal triamcinolone and elevated intraocular pressure","volume":"27","author":"Wingate","year":"1999","journal-title":"Aust N Z J Ophthalmol"},{"key":"R15-20261103","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.ajo.2004.06.067","article-title":"Intravitreal triamcinolone acetonide and intraocular pressure","volume":"138","author":"Smithen","year":"2004","journal-title":"Am J Ophthalmol"},{"key":"R16-20261103","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1016\/j.jcrs.2007.04.029","article-title":"Safety and efficacy of intraoperative intravitreal injection of triamcinolone acetonide injection after phacoemulsification in cases of uveitic cataract","volume":"33","author":"Dada","year":"2007","journal-title":"J Cataract Refract Surg"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_1015_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T18:01:34Z","timestamp":1793728894000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_1015_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,27]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_1015_25","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,27]]},"assertion":[{"value":"2025-04-23","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-31","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}