{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T13:23:25Z","timestamp":1788355405284,"version":"build-2803163510"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Pythium insidiosum<\/jats:italic>\n                    keratitis (PIK) is a devastating corneal infection resulting in blindness in a large number of cases. Clinically and morphologically, it closely mimics fungal keratitis, and hence is also labeled as \u201cparafungus.\u201d Although many clinical studies have documented evidence regarding the virulence of microorganism, and anatomical and functional outcomes, it remains a clinical challenge and diagnostic dilemma for most clinicians. Till today, PIK is being diagnosed and treated with certainty at only limited centers across the globe. But the question is why this is so? Taking this as the research question, this section on current ophthalmology aims to highlight the understanding of barriers to diagnosing and treating PIK, the suggestions to improve diagnosis and treatment, and the future prospects.\n                  <\/jats:p>","DOI":"10.4103\/ijo.ijo_1041_23","type":"journal-article","created":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T00:00:08Z","timestamp":1700438408000},"page":"3584-3586","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Understanding barriers, recommended solutions, and future prospects for the diagnosis and management of Pythium insidiosum keratitis"],"prefix":"10.4103","volume":"71","author":[{"given":"Bharat","family":"Gurnani","sequence":"first","affiliation":[{"name":"Cataract, Cornea, Trauma, External Disease, Ocular Surface and Refractive Services, Sadguru Netra Chikitsalya, Shri Sadguru Seva Sangh Trust, Chitrakoot, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirandeep","family":"Kaur","sequence":"additional","affiliation":[{"name":"Cataract, Pediatrics Ophthalmology and Strabismus Services, Sadguru Netra Chikitsalya, Shri Sadguru Seva Sangh Trust, Chitrakoot, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,11,20]]},"reference":[{"key":"R1-20260511","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.4103\/ijo.IJO_1534_21","article-title":"Pythium insidiosum keratitis-A review","volume":"70","author":"Gurnani","year":"2022","journal-title":"Indian J Ophthalmol"},{"key":"R2-20260511","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.4103\/ijo.IJO_1808_20","article-title":"Retrospective multifactorial analysis of Pythium keratitis and review of literature","volume":"69","author":"Gurnani","year":"2021","journal-title":"Indian J 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from patients of Pythium keratitis","volume":"70","author":"Gurnani","year":"2022","journal-title":"Indian J Ophthalmol"},{"key":"R6-20260511","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.4103\/ijo.IJO_3685_20","article-title":"Masked comparison of trypan blue stain and potassium hydroxide with calcofluor white stain in the microscopic examination of corneal scrapings for the diagnosis of microbial keratitis","volume":"69","author":"Rathi","year":"2021","journal-title":"Indian J Ophthalmol"},{"key":"R8-20260511","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1097\/ICO.0000000000001244","article-title":"Pythium insidiosum keratitis: Histopathology and rapid novel diagnostic staining technique","volume":"36","author":"Mittal","year":"2017","journal-title":"Cornea"},{"key":"R9-20260511","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1097\/ICO.0000000000002284","article-title":"Novel duplex polymerase chain reaction for the rapid detection of pythium 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