{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T12:46:45Z","timestamp":1792673205351,"version":"4.5.0"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,3]]},"abstract":"\n Purpose:<\/jats:title>\n This study aimed to evaluate the optic coherence tomography (OCT) findings in patients with toxoplasmic retinochoroiditis (TRC).<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n A total of 12 eyes of 12 patients with active TRC were included in the study. At baseline, at the first-month follow-up, at the sixth-month follow-up and at the 1-year follow-up, the TRC lesion OCT and macula OCT were evaluated.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Hyperreflectivity of the inner retinal layers and an increase in retinal thickness were observed on the OCT examinations of all the patients with an active TRC lesion. The retinal thickness decreased and the reflectivity of retinal layers was disorganized in the OCT images obtained in the follow-up period. Partial posterior hyaloid detachment (PHD) and no PHD were detected in 11 cases and 1 case, respectively. Epiretinal membrane (ERM) had developed in the adjacent region of the scar in 7 patients. With the regression of the lesion, the disruption of the ellipsoid zone (EZ), retinal pigment epithelium (RPE) and external limiting membrane (ELM) improved in the adjacent areas. In all the eyes, ERM and the PHD configuration did progress during the follow-up period. Vitreoschisis was found in 4 of the 11 patients with partial PHD. It was observed that ERM developed in all the patients with vitreoschisis.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n ERM and partial PHD were common in the TRC patients, and there was no progression during the follow-up period. Regeneration of the EZ, RPE and ELM was observed in the follow-up period.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1061_20","type":"journal-article","created":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T05:35:03Z","timestamp":1613540103000},"page":"630-634","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Optical coherence tomography findings in toxoplasma retinochoroiditis"],"prefix":"10.4103","volume":"69","author":[{"given":"Seda Karaca","family":"Ad\u0131yeke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neslisah Kutlu","family":"Uzakgider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u0131la","family":"Do\u011fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan","family":"Aytogan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Buket","family":"Aras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamze","family":"Ture","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekrem","family":"Talay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-35-20240828","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0002-9394(14)70532-X","article-title":"Causes of uveitis in the general practice of ophthalmology. UCLA Community-Based Uveitis Study Group","volume":"121","author":"McCannel","year":"1996","journal-title":"Am J Ophthalmol"},{"key":"R2-35-20240828","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1136\/bjo.80.12.1099","article-title":"Toxoplasma gondii and ocular toxoplasmosis: Pathogenesis","volume":"80","author":"Pavesio","year":"1996","journal-title":"Br J Ophthalmol"},{"key":"R3-35-20240828","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1136\/bjo.2007.124099","article-title":"The characteristic features of optical coherence tomography in posterior uveitis","volume":"91","author":"Gallagher","year":"2007","journal-title":"Br J Ophthalmol"},{"key":"R4-35-20240828","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1007\/s00417-006-0330-6","article-title":"Atypical spherical deposition on vitreoretinal interface associated with toxoplasmic chorioretinitis","volume":"245","author":"Guagnini","year":"2007","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R5-35-20240828","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1089\/jop.2016.0142","article-title":"Vitrectomy for epiretinal membranes and macular holes in uveitis patients","volume":"33","author":"Branson","year":"2017","journal-title":"J Ocul Pharmacol Ther"},{"key":"R6-35-20240828","doi-asserted-by":"crossref","first-page":"261","DOI":"10.4274\/tjo.77632","article-title":"Vitreomacular interface disorders in Beh\u00e7et's uveitis","volume":"47","author":"Eser \u00d6zt\u00fcrk","year":"2017","journal-title":"Turk J Ophthalmol"},{"key":"R7-35-20240828","doi-asserted-by":"crossref","first-page":"645","DOI":"10.2147\/OPTH.S20033","article-title":"Evaluation of spectral domain and time domain optical coherence tomography findings in toxoplasmic retinochoroiditis","volume":"5","author":"Diniz","year":"2011","journal-title":"Clin Ophthalmol"},{"key":"R8-35-20240828","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1136\/bjo.2006.108068","article-title":"Vitreoretinal morphology in active ocular toxoplasmosis: A prospective study by optical coherence tomography","volume":"91","author":"Or\u00e9fice","year":"2007","journal-title":"Br J Ophthalmol"},{"key":"R9-35-20240828","doi-asserted-by":"crossref","first-page":"376","DOI":"10.4103\/ijo.IJO_650_18","article-title":"Epiretinal membrane profile on spectral domain optical coherence tomography in patients with uveitis","volume":"67","author":"Maitra","year":"2019","journal-title":"Indian J Ophthalmol"},{"key":"R10-35-20240828","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.ajo.2006.03.037","article-title":"Third-generation optical coherence tomography findings in punctate retinal toxoplasmosis","volume":"142","author":"Or\u00e9fice","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"R11-35-20240828","doi-asserted-by":"crossref","first-page":"e0004685","DOI":"10.1371\/journal.pntd.0004685","article-title":"Toxoplasmic retinochoroiditis: Clinical characteristics and visual outcome in a prospective study","volume":"10","author":"Couto Aleixo","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"key":"R12-35-20240828","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/S0161-6420(02)01443-4","article-title":"Five-year cumulative incidence and progression of epiretinal membranes: The Blue Mountains Eye Study","volume":"110","author":"Fraser-Bell","year":"2003","journal-title":"Ophthalmology"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_1061_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:41:06Z","timestamp":1787845266000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_1061_20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_1061_20","relation":{},"ISSN":["0301-4738"],"issn-type":[{"value":"0301-4738","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]}}}