{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T13:36:31Z","timestamp":1793799391701,"version":"4.6.1"},"reference-count":60,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:p>Lowering of intraocular pressure is currently the only therapeutic measure for Glaucoma management. Many longterm, randomized trials have shown the efficacy of lowering IOP, either by a percentage of baseline, or to a specified level. This has lead to the concept of 'Target\u201d IOP, a range of IOP on therapy, that would stabilize the Glaucoma\/prevent further visual field loss, without significantly affecting a patient's quality of life. A clinical staging of Glaucoma by optic nerve head evaluation and perimetric parameters, allows a patient's eye to be categorized as having \u2013 mild, moderate or severe Glaucomatous damage. An initial attempt should be made to achieve the following IOP range for both POAG or PACG after an iridotomy. In mild glaucoma the initial target IOP range could be kept as 15-17 mmHg, for moderate glaucoma 12-15 mmHg and in the severe stage of glaucomatous damage 10-12 mmHg. Factoring in baseline IOP, age, vascular perfusion parameters, and change on perimetry or imaging during follow up, this range may be reassessed over 6 months to a year. \u201cTarget\u201d IOP requires further lowering when the patient continues to progress or develops a systemic disease such as a TIA. Conversely, in the event of a very elderly or sick patient with stable nerve and visual field over time, the target IOP could be raised and medications reduced. An appropriate use of medications\/laser\/surgery to achieve such a \u201cTarget\u201d IOP range in POAG or PACG can maintain visual fields and quality of life, preventing Glaucoma blindness.<\/jats:p>","DOI":"10.4103\/ijo.ijo_1130_17","type":"journal-article","created":{"date-parts":[[2018,3,26]],"date-time":"2018-03-26T01:46:39Z","timestamp":1522028799000},"page":"495-505","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":166,"title":["Simplifying \u201ctarget\u201d intraocular pressure for different stages of primary open-angle glaucoma and primary angle-closure glaucoma"],"prefix":"10.4103","volume":"66","author":[{"given":"Ramanjit","family":"Sihota","sequence":"first","affiliation":[{"name":"Glaucoma Research Facility & Clinical Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dewang","family":"Angmo","sequence":"additional","affiliation":[{"name":"Glaucoma Research Facility & Clinical Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepa","family":"Ramaswamy","sequence":"additional","affiliation":[{"name":"Glaucoma Research Facility & Clinical Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanuj","family":"Dada","sequence":"additional","affiliation":[{"name":"Glaucoma Research Facility & Clinical Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20251013","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/0039-6257(77)90043-1","article-title":"Progress in the treatment of glaucoma in my lifetime","volume":"21","author":"Chandler","year":"1977","journal-title":"Surv Ophthalmol"},{"key":"R2-20251013","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1185\/030079908X291976","article-title":"Treatment of glaucoma patients with insufficient intraocular pressure control: A survey of German ophthalmologists in private practice","volume":"24","author":"Vorwerk","year":"2008","journal-title":"Curr Med Res Opin"},{"key":"R3-20251013","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/S0161-6420(03)00564-5","article-title":"Glaucoma in a rural population of Southern India: The Aravind comprehensive eye survey","volume":"110","author":"Ramakrishnan","year":"2003","journal-title":"Ophthalmology"},{"key":"R4-20251013","doi-asserted-by":"crossref","first-page":"e76434","DOI":"10.1371\/journal.pone.0076434","article-title":"Prevalence and associated factors of glaucoma in rural central India. 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