{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:40:34Z","timestamp":1786653634424,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,6]]},"abstract":"\n Purpose:<\/jats:title>\n To study cases of Fuchs\u2019 uveitis (FU) diagnosed as uveitis other than FU at initial visits.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n A retrospective, observational chart review. Details of clinical presentation, initial diagnosis, treatment details, and follow-up before and after the diagnosis of FU was studied.<\/jats:p>\n <\/jats:sec>\n \n Result:<\/jats:title>\n Twenty eyes of 19 patients finally diagnosed with FU. Mean total follow-up was 39 months (range: 3\u2013120 months, median: 30 months) and follow-up after diagnosis of FU was 18 months (range: 0\u201384 months, median: 11 months). Most of the cases were diagnosed with anterior plus intermediate uveitis at the presentation (n = 8, 42.1%) and received steroid treatment. Keratic precipitates (KPs) typical of FU developed after mean 5.4 months of presentation (range: 1\u201318 months, median: 2 months). Altered iris pattern was noted after 17 months of presentation (range: 2\u201370 months, median: 8.5). Vitritis of grades 1\u20132 was present in all eyes. Overlap of uveitis of other etiology (retinal vasculitis, presumed tubercular intermediate uveitis) was found in three patients. Systemic immune disease (systemic lupus erythematosus, pulmonary sarcoidosis) was present in two patients. No treatment for the ocular inflammation was given after the diagnosis of FU in any patient and no change in the pattern of FU was observed during further follow-up.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Evolving FU may lead to misdiagnosis and mismanagement. We suggest a conservative approach, withholding steroid treatment, allowing FU to evolve, in otherwise asymptomatic patients with white eye, mild to moderate anterior chamber (AC) and vitreous inflammation, absent posterior synechiae and normal fundus examination or fundus examination suggestive of resolved uveitis.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1151_23","type":"journal-article","created":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T01:00:06Z","timestamp":1707181206000},"page":"885-889","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Evolving Fuchs\u2019 uveitis - A diagnostic challenge"],"prefix":"10.4103","volume":"72","author":[{"given":"Ankush","family":"Kawali","sequence":"first","affiliation":[{"name":"Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radhika","family":"Sriram","sequence":"additional","affiliation":[{"name":"Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Srinivasan","sequence":"additional","affiliation":[{"name":"Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padmamalini","family":"Mahendradas","sequence":"additional","affiliation":[{"name":"Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Shetty","sequence":"additional","affiliation":[{"name":"Department of Corneal and Refractive Surgery, Narayana Nethralaya, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,2,5]]},"reference":[{"key":"R1-20260504","doi-asserted-by":"crossref","first-page":"239","DOI":"10.4103\/0974-9233.58424","article-title":"Fuchs\u2019 uveitis: Failure to associate vitritis and disc hyperfluorescence with the disease is the major factor for misdiagnosis and diagnostic delay","volume":"16","author":"Bouchenaki","year":"2009","journal-title":"Middle East Afr J Ophthalmol"},{"key":"R2-20260504","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/j.1600-0420.1995.tb00661.x","article-title":"Fuchs\u2019 heterochromic iridocyclitis revisited","volume":"73","author":"Fearnley","year":"1995","journal-title":"Acta Ophthalmol Scand"},{"key":"R4-20260504","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1076\/ocii.10.2.125.13976","article-title":"Fuchs\u2019 heterochromic iridocyclitis: Clinical manifestations in dark-eyed Mexican patients","volume":"10","author":"Arellanes-Garc\u00eda","year":"2002","journal-title":"Ocul Immunol Inflamm"},{"key":"R5-20260504","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1038\/eye.1991.121","article-title":"Fuchs\u2019 Heterochromic Uveitis: A reappraisal of the clinical spectrum","volume":"5","author":"Jones","year":"1991","journal-title":"Eye (Lond)"},{"key":"R6-20260504","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1136\/bjophthalmol-2015-307246","article-title":"Iris autofluorescence in Fuchs\u2019 heterochromic uveitis","volume":"100","author":"Liu","year":"2016","journal-title":"Br J Ophthalmol"},{"key":"R7-20260504","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1007\/s00417-015-2960-z","article-title":"Clinical manifestation of Fuchs uveitis syndrome in childhood","volume":"253","author":"Tappeiner","year":"2015","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R8-20260504","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1038\/eye.2000.57","article-title":"Vitrectomy for vitreous opacification in Fuchs\u2019 heterochromic uveitis","volume":"14","author":"Waters","year":"2000","journal-title":"Eye (Lond)"},{"key":"R9-20260504","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.ajo.2004.02.055","article-title":"Fuchs heterochromic cyclitis: Rubella virus antibodies and genome in aqueous humor","volume":"138","author":"Quentin","year":"2004","journal-title":"Am J Ophthalmol"},{"key":"R10-20260504","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.ajo.2008.09.001","article-title":"Presumed Fuchs heterochromic iridocyclitis and Posner-Schlossman syndrome: Comparison of cytomegalovirus-positive and negative eyes","volume":"146","author":"Chee","year":"2008","journal-title":"Am J Ophthalmol"},{"key":"R11-20260504","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.ajo.2021.03.052","article-title":"Classification criteria for Fuchs uveitis syndrome","volume":"228","year":"2021","journal-title":"Am J Ophthalmol"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_1151_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:40:18Z","timestamp":1786650018000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_1151_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,5]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_1151_23","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,5]]},"assertion":[{"value":"2023-05-03","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}