{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:06:39Z","timestamp":1787169999303,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:p>We present a case of endogenous fungal endophthalmitis in a nondiabetic, nonhypertensive patient who recovered from COVID-19 infection. Endogenous fungal endophthalmitis in an immunocompetent individual is quite uncommon. The organism in our patient was resistant to amphotericin and voriconazole and was successfully treated with intravitreal caspofungin. The rarity of an opportunistic nosocomial infection in an immunocompetent person with a drug-resistant organism prompted us to write this report.<\/jats:p>","DOI":"10.4103\/ijo.ijo_1192_21","type":"journal-article","created":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T06:54:59Z","timestamp":1638255299000},"page":"3759-3761","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":14,"title":["Endogenous fungal endopthalmitis treated with intravitreal caspofungin in a COVID-19 recovered patient: A case report"],"prefix":"10.4103","volume":"69","author":[{"given":"Chinmay","family":"Nakhwa","sequence":"first","affiliation":[{"name":"Elixir Eye Care and Retina Center, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,11,26]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"e0241661","DOI":"10.1371\/journal.pone.0241661","article-title":"Ocular surface manifestations of coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis","volume":"15","author":"Aggarwal","year":"2020","journal-title":"PLoS One"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"2572","DOI":"10.4103\/ijo.IJO_2575_20","article-title":"Central retinal vein occlusion with COVID-19 infection as the presumptive etiology","volume":"68","author":"Walinjkar","year":"2020","journal-title":"Indian J Ophthalmol"},{"key":"B3-20240828","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.4103\/ijo.IJO_592_21","article-title":"Endogenous fungal endophthalmitis following intensive corticosteroid therapy in severe COVID-19 disease","volume":"69","author":"Shroff","year":"2021","journal-title":"Indian J Ophthalmol"},{"key":"B4-20240828","doi-asserted-by":"crossref","first-page":"827","DOI":"10.4103\/ijo.IJO_948_19","article-title":"Clinical profile and outcome of endogenous endophthalmitis at a quaternary referral centre in south India","volume":"68","author":"Pillai","year":"2020","journal-title":"Indian J Ophthalmol"},{"key":"B5-20240828","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1038\/s41433-020-01148-8","article-title":"Care for critically Ill patients with COVID-19: Don't forget the eyes","volume":"35","author":"Clough","year":"2021","journal-title":"Eye"},{"key":"B6-20240828","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1016\/S0140-6736(20)30920-X","article-title":"SARS-CoV-2 and viral sepsis: Observations and hypotheses","volume":"395","author":"Li","year":"2020","journal-title":"Lancet"},{"key":"B7-20240828","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1056\/NEJMoa2021436","article-title":"Dexamethasone in hospitalized patients with Covid-19","volume":"384","author":"Horby","year":"2021","journal-title":"N Engl J Med"},{"key":"B8-20240828","first-page":"137","article-title":"Distribution of Candida species in different clinical sources in Delhi, India, and proteinase and phospholipase activity of Candida albicans isolates","volume":"20","author":"Basu","year":"2003","journal-title":"Rev Iberoam Micol"},{"key":"B9-20240828","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1592\/phco.27.12.1711","article-title":"Candida endophthalmitis: Focus on current and future antifungal treatment options","volume":"27","author":"Khan","year":"2007","journal-title":"Pharmacotherapy"},{"key":"B10-20240828","doi-asserted-by":"crossref","first-page":"529","DOI":"10.4103\/ijo.IJO_781_16","article-title":"Management of a case of Candida albicans endogenous endophthalmitis with intravitreal caspofungin","volume":"65","author":"Yadav","year":"2017","journal-title":"Indian J Ophthalmol"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_1192_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:16:22Z","timestamp":1787166982000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_1192_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,26]]},"references-count":10,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_1192_21","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,26]]},"assertion":[{"value":"2021-05-12","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-28","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}