{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T18:00:40Z","timestamp":1789668040223,"version":"4.0.1"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>The present study aimed to assess the changes in optic disc and peripapillary retinal nerve fiber layer (RNFL) parameters in myopic patients and its correlation with axial length (AL) and spherical equivalent (SE) using optical coherence tomography (OCT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was a cross-sectional study carried out from August 2019 to September 2021 in the ophthalmology department of a tertiary care hospital in eastern India. Myopic patients in the age group of 20\u201340 years and SE between \u2212 0.5 to \u2212 10 Diopters (D) were included in the study. Patients were divided into two groups on the basis of degree of myopia and AL. Appropriate statistical analysis was done at the end of the study period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The study included 307 eyes of 307 myopic patients. There were 181 females (58.96%) and 126 males (41.04%). The mean age of the patients enrolled for the study was 28.78 \u00b1 5.76 years. Statistically significant difference (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) was found between SE and AL in between the subgroups of A and B. With every 1 D increase in SE, the average peripapillary RNFL thickness decreased by 0.61 m while with every 1 mm increase in AL, the average peripapillary RNFL thickness was found to reduce by 1.03 m.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Analysis of optic nerve head parameters and RNFL thickness by OCT for the diagnosis should be compared with a normative control group that has been matched for refractive error and AL instead of comparison with a normative database that has only been age matched.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1229_22","type":"journal-article","created":{"date-parts":[[2022,12,6]],"date-time":"2022-12-06T08:53:31Z","timestamp":1670316811000},"page":"4343-4348","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":9,"title":["Assessment of changes in optic disc parameters and peripapillary retinal nerve fiber layer thickness in myopic patients and its correlation with axial length and degree of myopia"],"prefix":"10.4103","volume":"70","author":[{"given":"Alpana","family":"Mishra","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan (deemed to be) University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lolly","family":"Pattnaik","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan (deemed to be) University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suchismita","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan (deemed to be) University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep Kumar","family":"Panigrahi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan (deemed to be) University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smaraki","family":"Mohanty","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan (deemed to be) University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,11,30]]},"reference":[{"key":"R1-20251006","doi-asserted-by":"crossref","first-page":"e0240750","DOI":"10.1371\/journal.pone.0240750","article-title":"Prevalence of myopia in Indian school children:Meta-analysis of last four decades","volume":"15","author":"Agarwal","year":"2020","journal-title":"PLoS One"},{"key":"R2-20251006","doi-asserted-by":"crossref","first-page":"83","DOI":"10.4103\/0970-0218.112436","article-title":"Is myopia a public health problem in India?","volume":"38","author":"Saxena","year":"2013","journal-title":"Indian J Community Med"},{"key":"R3-20251006","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.ophtha.2016.01.006","article-title":"Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050","volume":"123","author":"Holden","year":"2016","journal-title":"Ophthalmology"},{"key":"R4-20251006","doi-asserted-by":"crossref","first-page":"939","DOI":"10.4103\/ijo.IJO_974_21","article-title":"Myopia prevalence in a population-based childhood visual impairment study in North India-CHVI-2","volume":"70","author":"Wadhwani","year":"2022","journal-title":"Indian J Ophthalmol"},{"key":"R5-20251006","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1475-1313.2005.00298.x","article-title":"Myopia and associated pathological complications","volume":"25","author":"Saw","year":"2005","journal-title":"Ophthalmic Physiol Opt"},{"key":"R6-20251006","first-page":"874","article-title":"Optic disc and peripapillary changes by optic coherence tomography in high myopia","volume":"11","author":"Pan","year":"2018","journal-title":"Int J Ophthalmol"},{"key":"R7-20251006","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1001\/jamaophthalmol.2021.3303","article-title":"Continued increase of axial length and its risk factors in adults with high myopia","volume":"139","author":"Du","year":"2021","journal-title":"JAMA Ophthalmol"},{"key":"R8-20251006","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1136\/bjo.53.11.765","article-title":"Ratio of optic cup to optic disc. 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