{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T14:03:45Z","timestamp":1786716225143,"version":"build-2736575974"},"reference-count":96,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:p>Preterm babies with retinopathy of prematurity (ROP) can become blind if they do not receive appropriate timely intervention. The presence of cataract in these individuals in addition to visual deprivation amblyopia, also delays proper screening, adequate treatment, and makes follow-up assessment difficult. Anatomical differences in these infants and amblyopia management, especially in unilateral cataract, are other important concerns, and hence, management of these cases with cataract and ROP is challenging. In this review, studies where ROP cases were associated with cataract, were evaluated with a focus on preterm individuals less than 6 months age. Preterm babies are at increased risk of developing cataract because of systemic factors. In addition, those with ROP may have cataract associated with retinal detachment or treatment received. The type of cataract, risk factors, and pathophysiology associated with each cause varies. This review highlights these different aspects of cataract in ROP including causes, pathophysiology, types of cataracts, and management. The management of these cases is critical in terms of the timing of cataract surgery and the challenges associated with surgery and posterior segment management for ROP. Anatomical differences, preoperative retina status, pupillary dilatation, neovascularization of iris in aggressive posterior ROP, fundus examination, amblyopia, and follow-up are various important aspects in the management of the same. The preoperative workup, intraoperative challenges, postoperative care, and rehabilitation in these individuals are discussed.<\/jats:p>","DOI":"10.4103\/ijo.ijo_125_21","type":"journal-article","created":{"date-parts":[[2022,2,16]],"date-time":"2022-02-16T07:51:02Z","timestamp":1644997862000},"page":"369-377","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":11,"title":["Cataract in retinopathy of prematurity \u2013 A review"],"prefix":"10.4103","volume":"70","author":[{"given":"Sudarshan","family":"Khokhar","sequence":"first","affiliation":[{"name":"Cataract and Refractive Service, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"},{"name":"Dr. Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhidnya","family":"Surve","sequence":"additional","affiliation":[{"name":"Cataract and Refractive Service, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"},{"name":"Vitreoretinal, Uvea and ROP Service, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"},{"name":"Dr. Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saurabh","family":"Verma","sequence":"additional","affiliation":[{"name":"Cataract and Refractive Service, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"},{"name":"Vitreoretinal, Uvea and ROP Service, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"},{"name":"Dr. Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shorya","family":"Azad","sequence":"additional","affiliation":[{"name":"Vitreoretinal, Uvea and ROP Service, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"},{"name":"Dr. Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parijat","family":"Chandra","sequence":"additional","affiliation":[{"name":"Vitreoretinal, Uvea and ROP Service, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"},{"name":"Dr. Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chirakshi","family":"Dhull","sequence":"additional","affiliation":[{"name":"Cataract and Refractive Service, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"},{"name":"Vitreoretinal, Uvea and ROP Service, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"},{"name":"Dr. Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajpal","family":"Vohra","sequence":"additional","affiliation":[{"name":"Vitreoretinal, Uvea and ROP Service, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"},{"name":"Dr. Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,1,27]]},"reference":[{"key":"R1-20251006","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S0039-6257(96)82011-X","article-title":"Infantile cataracts","volume":"40","author":"Lambert","year":"1996","journal-title":"Surv Ophthalmol"},{"issue":"Suppl 1","key":"R2-20251006","doi-asserted-by":"crossref","first-page":"S108","DOI":"10.4103\/ijo.IJO_1827_19","article-title":"Operational guidelines for ROP in India: A Summary","volume":"68","author":"Shukla","year":"2020","journal-title":"Indian J Ophthalmol"},{"key":"R3-20251006","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1136\/bjophthalmol-2016-309392","article-title":"Cataract surgery in children with retinopathy of prematurity (ROP): Surgical outcomes","volume":"101","author":"Ezisi","year":"2017","journal-title":"Br J Ophthalmol"},{"key":"R4-20251006","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jaapos.2012.10.011","article-title":"Early Treatment for Retinopathy of Prematurity Cooperative Group. 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