{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T06:58:58Z","timestamp":1793429938097,"version":"4.5.0"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>Age is an important risk factor for both glaucoma and cataract. As global life expectancy continues to rise, the prevalence of concomitant open-angle glaucoma (OAG) and cataracts is increasing. Currently, there is a lack of definitive consensus on the optimal management approach for such individuals. Conventionally, trabeculectomy (Trab) in combination with phacoemulsification is the preferred method. Recent developments in microinvasive glaucoma surgery (MIGS), which offer similar results with fewer complications, provide a new possible approach to this condition. This study aimed to assess the current knowledge of combination surgery in patients with cataract and OAG to provide a comprehensive understanding and help its implementation in clinical settings. A comprehensive systematic search was conducted in May 2021 on five databases (MEDLINE, Embase, SCOPUS, Proquest, EBSCO, and Cochrane Library). The results were filtered for English and human studies but not publication year. All studies published up to May 2021 were reviewed. Newcastle\u2013Ottawa Scale and PEDro scale were used to screen studies for risk of bias where appropriate. Four studies satisfied the inclusion criteria and were subsequently added in this review. Study designs consisted of one RCT and three descriptive studies. Appropriate assessment tools were used; these studies demonstrated moderate to good quality. Postoperative mean IOP, IOP reduction, and qualified success rates were comparable in the Phaco-MIGS (Phaco-endoscopic cyclophotocoagulation (ECP), Phaco-ab interno trabeculectomy (AIT)) and Phaco-Trab group. Severe complication was reported only in the latter. Phaco-MIGS (in particular, trabectome) shows excellent promise as an option for individuals with OAG and concomitant cataract; further research through RCT is required to validate these findings.<\/jats:p>","DOI":"10.4103\/ijo.ijo_1322_23","type":"journal-article","created":{"date-parts":[[2024,4,20]],"date-time":"2024-04-20T04:00:28Z","timestamp":1713585628000},"page":"S345-S353","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":15,"title":["Comparison between MIGS with trabeculectomy in the management of open-angle glaucoma with cataract: A systematic review"],"prefix":"10.4103","volume":"72","author":[{"given":"Abritho","family":"Zaifar","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Kirana Eye Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiara Grevillea","family":"Pratomo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Kirana Eye Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrianda Nadya","family":"Suryono","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Kirana Eye Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,3,8]]},"reference":[{"key":"R1-20260504","first-page":"225","article-title":"The diagnosis and treatment of glaucoma","volume":"117","author":"Schuster","year":"2020","journal-title":"Dtsch Arztebl Int"},{"key":"R2-20260504","article-title":"Glaucoma in the developing world","author":"Aref","year":"2023","journal-title":"Am Acad Ophthalmol"},{"key":"R3-20260504","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","article-title":"Global prevalence of glaucoma and projections of glaucoma burden through 2040: A systematic review and meta-analysis","volume":"121","author":"Tham","year":"2014","journal-title":"Ophthalmology"},{"key":"R4-20260504","doi-asserted-by":"crossref","first-page":"e144","DOI":"10.1016\/S2214-109X(20)30489-7","article-title":"Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: The Right to Sight: An analysis for the Global Burden of Disease Study","volume":"9","year":"2021","journal-title":"Lancet Glob Health"},{"key":"R5-20260504","doi-asserted-by":"crossref","first-page":"4254","DOI":"10.1167\/iovs.06-0299","article-title":"Variations in primary open-angle glaucoma prevalence by age, gender, and race: A Bayesian meta-analysis","volume":"47","author":"Rudnicka","year":"2006","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R6-20260504","doi-asserted-by":"crossref","first-page":"605814","DOI":"10.1155\/2015\/605814","article-title":"The prevalence of age-related eye diseases and cataract surgery among older adults in the city of Lodz, Poland","volume":"2015","author":"Nowak","year":"2015","journal-title":"J Ophthalmol"},{"key":"R7-20260504","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.joco.2018.05.003","article-title":"Prevalence and risk factors of glaucoma in an adult population from Shahroud, Iran","volume":"31","author":"Hashemi","year":"2018","journal-title":"J Curr Ophthalmol"},{"key":"R10-20260504","first-page":"CD008671","article-title":"Combined surgery versus cataract surgery alone for eyes with cataract and glaucoma","volume":"2015","author":"Zhang","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"R11-20260504","article-title":"Techniques for combined cataract and filtering glaucoma surgery","author":"Wisner","year":"2023","journal-title":"American Academy of Ophthalmology"},{"key":"R12-20260504","doi-asserted-by":"crossref","first-page":"2532","DOI":"10.1016\/j.ophtha.2013.07.049","article-title":"Trabeculectomy in the 21st century: A multicenter analysis","volume":"120","author":"Kirwan","year":"2013","journal-title":"Ophthalmology"},{"key":"R13-20260504","doi-asserted-by":"crossref","first-page":"3182935","DOI":"10.1155\/2017\/3182935","article-title":"Safety and efficacy of microinvasive glaucoma surgery","volume":"2017","author":"Chen","year":"2017","journal-title":"J Ophthalmol"},{"key":"R14-20260504","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1080\/17469899.2017.1335597","article-title":"Microinvasive glaucoma surgery: An evidence-based assessment","volume":"12","author":"Schehlein","year":"2017","journal-title":"Expert Rev Ophthalmol"},{"key":"R15-20260504","article-title":"Microinvasive Glaucoma Surgery (MIGS)","author":"Aref","year":"2023","journal-title":"American Academy of Ophthalmology;"},{"key":"R16-20260504","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.2147\/OPTH.S293702","article-title":"Microinvasive glaucoma surgery: A review of Schlemm\u2019s canal-based procedures","volume":"15","author":"Konopi\u0144ska","year":"2021","journal-title":"Clin Ophthalmol"},{"key":"R17-20260504","article-title":"Newcastle-Ottawa Quality Assessment form for cohort studies","year":"2023"},{"key":"R18-20260504","article-title":"PEDro scale"},{"key":"R19-20260504","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.jcjo.2018.01.033","article-title":"Prospective randomized controlled trial of phaco-trabectome versus phaco-trabeculectomy in patients with open angle glaucoma","volume":"53","author":"Ting","year":"2018","journal-title":"Can J Ophthalmol"},{"key":"R20-20260504","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1007\/s00417-019-04341-y","article-title":"XEN implant device versus trabeculectomy, either alone or in combination with phacoemulsification, in open-angle glaucoma patients","volume":"257","author":"Marcos Parra","year":"2019","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R21-20260504","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1055\/s-0043-100291","article-title":"Long-term efficacy of combined phacoemulsification plus trabeculectomy versus phacoemulsification plus excimer laser trabeculotomy","volume":"234","author":"T\u00f6teberg-Harms","year":"2017","journal-title":"Klin Monbl Augenheilkd"},{"key":"R22-20260504","doi-asserted-by":"crossref","first-page":"5149154","DOI":"10.1155\/2018\/5149154","article-title":"Combined phacoendoscopic cyclophotocoagulation versus combined phacotrabeculectomy in the management of coexisting cataract and glaucoma: A comparative study","volume":"2018","author":"Lau","year":"2018","journal-title":"J Ophthalmol"},{"key":"R23-20260504","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/0002-9394(68)91288-9","article-title":"Trabeculectomy. Preliminary report of a new method","volume":"66","author":"Cairns","year":"1968","journal-title":"Am J Ophthalmol"},{"key":"R24-20260504","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.21037\/atm-20-6354","article-title":"XEN gel implant with or without phacoemulsification for glaucoma: A systematic review and meta-analysis","volume":"8","author":"Wang","year":"2020","journal-title":"Ann Transl Med"},{"key":"R25-20260504","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/S0161-6420(96)30639-8","article-title":"Bleb-related endophthalmitis after trabeculectomy with mitomycin C","volume":"103","author":"Higginbotham","year":"1996","journal-title":"Ophthalmology"},{"key":"R26-20260504","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1001\/archopht.1996.01100140151007","article-title":"Endophthalmitis after filtering surgery with mitomycin","volume":"114","author":"Greenfield","year":"1996","journal-title":"Arch Ophthalmol"},{"key":"R27-20260504","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1016\/S0886-3350(99)00141-8","article-title":"Combined cataract and glaucoma surgery: Trabeculectomy versus endoscopic laser cycloablation","volume":"25","author":"Gayton","year":"1999","journal-title":"J Cataract Refract Surg"},{"key":"R28-20260504","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2415-13-24","article-title":"Cataract surgery combined with excimer laser trabeculotomy to lower intraocular pressure: Effectiveness dependent on preoperative IOP","volume":"13","author":"T\u00f6teberg-Harms","year":"2013","journal-title":"BMC Ophthalmol"},{"key":"R29-20260504","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s40662-020-00190-7","article-title":"Current review of excimer laser trabeculostomy","volume":"7","author":"Durr","year":"2020","journal-title":"Eye Vis (Lond)"},{"key":"R30-20260504","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.tjo.2011.12.003","article-title":"Bleb-related infection: Clinical features and management","volume":"2","author":"Yamamoto","year":"2012","journal-title":"Taiwan J Ophthalmol"},{"key":"R31-20260504","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.survophthal.2017.01.009","article-title":"Trabeculectomy bleb-associated infections","volume":"62","author":"Razeghinejad","year":"2017","journal-title":"Surv Ophthalmol"},{"key":"R32-20260504","doi-asserted-by":"crossref","first-page":"100830","DOI":"10.1016\/j.ajoc.2020.100830","article-title":"Endophthalmitis following combined cataract extraction and placement of an iStent trabecular bypass device","volume":"20","author":"Chaves","year":"2020","journal-title":"Am J Ophthalmol Case Rep"},{"key":"R33-20260504","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1136\/bjophthalmol-2015-307131","article-title":"Review and meta-analysis of ab-interno trabeculectomy outcomes","volume":"100","author":"Kaplowitz","year":"2016","journal-title":"Br J Ophthalmol"},{"key":"R34-20260504","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1097\/01.ijg.0000196653.77836.af","article-title":"Ab interno trabeculectomy: Development of a novel device (Trabectome) and surgery for open-angle glaucoma","volume":"15","author":"Francis","year":"2006","journal-title":"J Glaucoma"},{"key":"R35-20260504","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.ajo.2005.03.031","article-title":"The tube versus trabeculectomy study: Design and baseline characteristics of study patients","volume":"140","author":"Gedde","year":"2005","journal-title":"Am J Ophthalmol"},{"key":"R36-20260504","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/sj.eye.6701477","article-title":"A review of trabeculectomy in East Asian people--the influence of race","volume":"19","author":"Husain","year":"2005","journal-title":"Eye (Lond)"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_1322_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:42:33Z","timestamp":1786650153000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_1322_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,8]]},"references-count":34,"journal-issue":{"issue":"Suppl 3","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_1322_23","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,8]]},"assertion":[{"value":"2023-05-21","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-08","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}