{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:32:48Z","timestamp":1786739568094,"version":"build-2736575974"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>Structural differences have been described in the retina of prematurely born children, including increased macular thickness caused by failed migration of the inner retina during development and retinal nerve fiber layer (RNFL) thinning related to low birth weight. The present study aimed to evaluate the differences in macular and RNFL optical coherence tomography (OCT) findings between full-term and preterm children without retinopathy of prematurity (ROP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Thirty-four premature (study group) and 43 full-term patients (control group)\u2014aged 3 to 8 years\u2014were studied. All children underwent a complete ophthalmological exam and OCT of the macula and optic nerve in both eyes to determine macular and RNFL thickness and morphology. Correlation analysis between central macular thickness, age, and visual acuity was also performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Central macular thickness was greater in the study group than in the control group; a difference of 14.2 \u03bcm was observed for the right eye (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.002) and 12.16 \u03bcm for the left eye (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.019). The thickness of the parafoveal and the perifoveal zones was consistently greater in the study group. 44.3% of eyes in the study group had mild forms of foveal hypoplasia (grades 1a and 1b) in qualitative description. No correlation between central macular thickness and visual acuity was found. There was no difference in RNFL thickness between both groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Statistically significant structural differences were found in the macula of premature children, with a greater foveal thickness possibly reflecting retention of the inner retina during development, with no repercussion over visual acuity. RNFL thickness was similar in both groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_137_21","type":"journal-article","created":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T10:22:48Z","timestamp":1627899768000},"page":"2151-2156","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["A comparison of posterior segment optical coherence tomography findings in full-term and preterm children without retinopathy of prematurity"],"prefix":"10.4103","volume":"69","author":[{"given":"Claudia J","family":"Mart\u00ednez-C\u00f3rdoba","sequence":"first","affiliation":[{"name":"Ophthalmology and Optometry Department - Hospital Militar Central, Bogot\u00e1, Colombia"},{"name":"Medical and Surgical Specialties Unit - Universidad Militar Nueva Granada, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernardo A","family":"Quijano-Nieto","sequence":"additional","affiliation":[{"name":"Ophthalmology and Optometry Department - Hospital Militar Central, Bogot\u00e1, Colombia"},{"name":"Medical and Surgical Specialties Unit - Universidad Militar Nueva Granada, Bogot\u00e1, Colombia"},{"name":"Macula and Retina Institute - Oftalmo Center, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia L","family":"Echeverr\u00eda-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Medical and Surgical Specialties Unit - Universidad Militar Nueva Granada, Bogot\u00e1, Colombia"},{"name":"Pediatrics and Neonatology Department - Hospital Militar Central, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa M","family":"Sierra-Bernal","sequence":"additional","affiliation":[{"name":"Ophthalmology and Optometry Department - Hospital Militar Central, Bogot\u00e1, 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