{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:28:43Z","timestamp":1786649323262,"version":"build-2736575974"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T00:00:00Z","timestamp":1734998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To study the prevalence, clinical presentation, treatment, and follow-up of ocular (dermal) melanocytosis (ODM) and its association with choroidal melanoma (CM) in Asian Indian patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was a retrospective case series of patients with ODM conducted in a quaternary eye care center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of the total 1.48 million patients during the study period, we identified 213 patients with ODM with a prevalence rate of 0.014%. Median age at presentation was 13 years (range 0\u201376 years). Unilateral presentation of ODM was noted in 87% cases. ODM involved the sclera in 100% cases, the iris in 23%, the choroid in 20%, the eyelid in 29%, and V1 and V2 dermatomes in 53% cases. Nineteen patients (9%) were found to have CM, with 1.3 times increased risk of CM compared to the Caucasian population. The most common tumor location was in the inferior quadrant (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 8, 44%). The mean tumor thickness was 8.3 \u00b1 2.8 mm with a mean basal diameter of 14.0 \u00b1 4.3 mm. Primary treatment of CM included plaque brachytherapy (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 6), enucleation (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 9), and few patients refused for treatment (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 3). During a mean follow-up period of 21 months, one patient died because of lung metastasis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Although rare, choroidal melanoma does occur in the presence of ODM with an increased risk in Asian Indians compared to the Caucasian population. Patients with ODM should be examined periodically for early detection of CM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1445_24","type":"journal-article","created":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T10:01:16Z","timestamp":1735034476000},"page":"S88-S94","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Oculodermal melanocytosis in Asian Indian patients: Prevalence, clinical presentation, and association with choroidal melanoma"],"prefix":"10.4103","volume":"73","author":[{"given":"Prapti","family":"Chheda","sequence":"first","affiliation":[{"name":"Anant Bajaj Retina Institute, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srishti","family":"Ramamurthy","sequence":"additional","affiliation":[{"name":"Anant Bajaj Retina Institute, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal","family":"Raval","sequence":"additional","affiliation":[{"name":"Anant Bajaj Retina Institute, Hyderabad, Telangana, India"},{"name":"The Operation Eyesight Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swathi","family":"Kaliki","sequence":"additional","affiliation":[{"name":"The Operation Eyesight Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,12,24]]},"reference":[{"key":"R1-20260424","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0161-6420(98)92205-9","article-title":"Lifetime prevalence of uveal melanoma in white patients with oculo (dermal) melanocytosis","volume":"105","author":"Singh","year":"1998","journal-title":"Ophthalmology"},{"key":"R2-20260424","first-page":"25","article-title":"Nevus of Ota in children","volume":"82","author":"Sinha","year":"2008","journal-title":"Cutis"},{"key":"R3-20260424","first-page":"176","article-title":"Ocular and oculodermal melanocytosis","volume":"20","author":"Gonder","year":"1985","journal-title":"Can J Ophthalmol"},{"key":"R4-20260424","doi-asserted-by":"crossref","first-page":"524","DOI":"10.3109\/08820538.2015.1118133","article-title":"An update on oculodermal melanocytosis and rare associated conditions","volume":"32","author":"Plateroti","year":"2017","journal-title":"Semin Ophthalmol"},{"key":"R5-20260424","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1001\/archderm.1967.01600320043006","article-title":"Natural history of nevus of Ota","volume":"95","author":"Hidano","year":"1967","journal-title":"Arch Dermatol"},{"key":"R6-20260424","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0161-6420(84)34261-0","article-title":"Orbital malignant melanoma and oculodermal melanocytosis: Report of two cases and review of the literature","volume":"91","author":"Dutton","year":"1984","journal-title":"Ophthalmology"},{"key":"R7-20260424","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1055\/s-2008-1045981","article-title":"[Ocular melanocytosis, oculodermal melanocytosis and choroid melanomas]","volume":"198","author":"Bercher","year":"1991","journal-title":"Klin Monbl Augenheilkd"},{"key":"R8-20260424","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/S0161-6420(82)34694-1","article-title":"Uveal malignant melanoma associated with ocular and oculodermal melanocytosis","volume":"89","author":"Gonder","year":"1982","journal-title":"Ophthalmology"},{"key":"R9-20260424","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1001\/archopht.1967.00980020333007","article-title":"Histogenesis of malignant melanomas of the uvea. 3. 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