{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:21:44Z","timestamp":1787761304899,"version":"build-2784847793"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>The aim of the study was to evaluate the outcomes of cataract surgery in patients of the pediatric age group with systemic comorbidities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Medical records of 54 eyes (30 patients) of the pediatric age group with systemic comorbidities who had undergone cataract surgery in a tertiary-care center were reviewed. The following parameters were recorded: systemic comorbidity; toxoplasmosis, rubella, cytomegalovirus, herpes simplex, HIV (TORCH) profile, best spectacle-corrected visual acuity (BSCVA), strabismus, nystagmus, and cataract morphology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Thirty patients with a mean age of 55 months (9 months\u201314 years) were included. On average, every child was seen by three physicians, and the mean duration between the first visit to a physician and presentation to our center was 2.23 \u00b1 0.67 years. The various causes for delay in referral include multiple referrals due to a lack of general anesthesia services in 78% of cases, a long waiting list at the referral hospital in 35% of cases, and a lack of awareness at the primary-care physician level in 50% of cases. The mean BSCVA at presentation was 1.4 logMAR (0.3 to 3 logMAR). The most common cataract morphology was that of zonular cataract (31.48%; 17\/54). Strabismus and abnormal eye movements were observed in 27.7% (15\/54) and 33.3% (18\/54) of eyes, respectively. Various systemic associations were periventricular leukomalacia (12\/30), Down\u2019s syndrome (6\/30), seizure disorder (6\/30), cardiac valvular anomalies (6\/30), Marfan\u2019s syndrome (4\/30), hypothyroidism (4\/30), rubella (3\/20), cytomegalovirus (3\/20), cerebral palsy (2\/30), nephrotic syndrome (2\/30), Type 1 diabetes mellitus (1\/30), microcephaly (1\/30), cryptogenic West syndrome (1\/30), congenital rubella syndrome (1\/30), and Tourette syndrome (1\/30). The mean postoperative corrected distance visual acuity (CDVA) at 2-year follow-up improved to 1.0 logMAR (0 to 3 logMAR). No postoperative complications were reported at the final follow-up. Around 70% of the parents reported improvement in their child\u2019s psychomotor skills.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Intellectually impaired pediatric patients with cataract should be operated upon whenever there is a presence of infrastructure, and unnecessary delay in surgery should be avoided by referring the patient to higher centers. Even though objective improvement in visual acuity was suboptimal, there was definitely an improvement in the psychomotor skills of the patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1465_22","type":"journal-article","created":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T09:14:27Z","timestamp":1672910067000},"page":"125-137","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Cataract surgery outcomes in pediatric patients with systemic comorbidities"],"prefix":"10.4103","volume":"71","author":[{"given":"Sohini","family":"Mandal","sequence":"first","affiliation":[{"name":"Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prafulla K","family":"Maharana","sequence":"additional","affiliation":[{"name":"Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritu","family":"Nagpal","sequence":"additional","affiliation":[{"name":"Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivani","family":"Joshi","sequence":"additional","affiliation":[{"name":"Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manpreet","family":"Kaur","sequence":"additional","affiliation":[{"name":"Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Sinha","sequence":"additional","affiliation":[{"name":"Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tushar","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Namrata","family":"Sharma","sequence":"additional","affiliation":[{"name":"Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeewan S","family":"Titiyal","sequence":"additional","affiliation":[{"name":"Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,12,30]]},"reference":[{"key":"R1-20240828","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.jfo.2014.10.012","article-title":"Epidemiologic and etiological characteristics of congenital cataract:Study of 59 cases over 10 years","volume":"38","author":"Fakhoury","year":"2015","journal-title":"J Fr Ophtalmol"},{"key":"R2-20240828","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1038\/s41433-019-0426-y","article-title":"Intra-lenticular lens aspiration in paediatric cases with anterior dislocation of lens","volume":"33","author":"Sahay","year":"2019","journal-title":"Eye (Lond)"},{"key":"R3-20240828","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1038\/eye.2017.160","article-title":"Modified technique of endocapsular lens aspiration for severely subluxated lenses","volume":"32","author":"Khokhar","year":"2018","journal-title":"Eye (Lond)"},{"key":"R4-20240828","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1001\/archophthalmol.2011.268","article-title":"Outcomes of pediatric cataract surgery at a tertiary care center in rural southern Ethiopia","volume":"129","author":"Tomkins","year":"2011","journal-title":"Arch Ophthalmol"},{"key":"R5-20240828","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.joco.2015.11.001","article-title":"Long-term visual outcome of congenital cataract at a Tertiary referral center from 2004 to 2014","volume":"27","author":"Rajavi","year":"2016","journal-title":"J Curr Ophthalmol"},{"key":"R6-20240828","first-page":"1245","article-title":"Gender inequalities in surgery for bilateral cataract among children in low-income countries","volume":"123","author":"Gilbert","year":"2016","journal-title":"A systematic review. 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