{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:30:40Z","timestamp":1787758240615,"version":"build-2784847793"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:p>Internuclear ophthalmoplegia (INO) is a neuro-ophthalmic disorder caused by damage in the medial longitudinal fasciculus between the third and sixth cranial nerve nuclei. We present a 4-year-old female diagnosed with INO triggered by coronavirus disease 2019 (COVID-19) infection. The patient had history of neonatal meningitis with hydrocephalus without history of surgical intervention. To the best of our knowledge, this is the first case with combined COVID-19 and chronic hydrocephalus as an etiology for INO in a child. COVID-19 may trigger neurological manifestations as INO in susceptible cases.<\/jats:p>","DOI":"10.4103\/ijo.ijo_1482_22","type":"journal-article","created":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T11:10:13Z","timestamp":1665054613000},"page":"3719-3721","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["COVID-19 provoked internuclear ophthalmoplegia in a child with arrested hydrocephalus"],"prefix":"10.4103","volume":"70","author":[{"given":"Mohamed","family":"Fathy","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Farwanyia Hospital, Kuwait, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salah","family":"Alrashidi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Farwanyia Hospital, Kuwait, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherein M","family":"Hagras","sequence":"additional","affiliation":[{"name":"Mansoura University Faculty of Medicine, Mansoura, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,9,30]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1148\/rg.331125033","article-title":"Brainstem pathways for horizontal eye movement: Pathologic correlation with MR imaging","volume":"33","author":"Bae","year":"2013","journal-title":"Radiographics"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1001\/archneur.62.5.714","article-title":"Internuclear ophthalmoplegia: Unusual causes in 114 of 410 patients","volume":"62","author":"Keane","year":"2005","journal-title":"Arch Neurol"},{"key":"B4-20240828","doi-asserted-by":"crossref","first-page":"e241873","DOI":"10.1136\/bcr-2021-241873","article-title":"Internuclear ophthalmoplegia as a presenting feature in a COVID-19-positive patient","volume":"14","author":"Vasanthpuram","year":"2021","journal-title":"BMJ Case Rep"},{"key":"B5-20240828","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1001\/archneurol.2010.60","article-title":"Wall-eyed bilateral internuclear ophthalmoplegia after ruptured aneurysm","volume":"67","author":"Jacob","year":"2010","journal-title":"Arch Neurol"},{"key":"B6-20240828","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1007\/s003810000383","article-title":"Disorders of CSF hydrodynamics","volume":"16","author":"Johnston","year":"2000","journal-title":"Childs Nerv Syst"},{"key":"B7-20240828","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/ICU.0000000000000707","article-title":"Neuro-ophthalmic manifestations of coronavirus disease 19","volume":"31","author":"Tisdale","year":"2020","journal-title":"Curr Opin Ophthalmol"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_1482_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:10:32Z","timestamp":1787757032000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_1482_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,30]]},"references-count":6,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_1482_22","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,30]]},"assertion":[{"value":"2022-06-22","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-08","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}