{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:20:59Z","timestamp":1787502059380,"version":"build-2736575974"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T00:00:00Z","timestamp":1735257600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate retinal vascular changes by optical coherence tomography angiography (OCTA) in multisystem inflammatory syndrome in children (MIS-C).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This cross-sectional study included 21 patients who were diagnosed with MIS-C and had a history of hospitalization, 20 pediatric outpatients with a coronavirus disease 2019 (COVID-19) diagnosis, and 26 healthy children. All patients underwent a detailed ophthalmologic examination and OCTA. In the MIS-C and pediatric COVID-19 groups, these evaluations were made 6 months after diagnosis. The vascular density values of the superficial, deep, and radial peripapillary capillary plexuses (SCP, DCP, and RPCP, respectively), foveal avascular zone (FAZ) parameters (area, perimeter, acircularity index, and foveal density), and outer retinal and choriocapillaris flow area values were recorded using OCTA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      No pathology was detected in the ophthalmologic examinations of the three groups with similar age and gender distributions. Although the vascular density values of SCP, DCP, and RPCP were found to be higher in most quadrants in the MIS-C group, there was no statistically significant difference among the three groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05 for all). FAZ parameters and flow area measurements were similar in all three groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05 for all).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This is the first study to evaluate relatively long-term outcomes in patients with MIS-C and pediatric COVID-19 together. This study shows no changes in the SCP and DCP parameters in pediatric age group, which shows that ocular hemodynamic changes may not be reflected on OCTA after 6 months.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1527_24","type":"journal-article","created":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T10:00:30Z","timestamp":1735293630000},"page":"725-730","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Ocular hemodynamics in multisystem inflammatory syndrome in children: A cross-sectional study"],"prefix":"10.4103","volume":"73","author":[{"given":"Sule Gokcek Gurturk","family":"Icoz","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Yozgat City Hospital, Yozgat, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mucella Ar\u0131kan","family":"Yorgun","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Y\u0131ld\u0131r\u0131m Beyaz\u0131t University Faculty of Medicine, Ankara, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gulsum Iclal","family":"Bayhan","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Disease, Ankara City Hospital, Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University Faculty of Medicine, Ankara, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Icoz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Yozgat City Hospital, Yozgat, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aysun","family":"Yahsi","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Disease, Ankara City Hospital, Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University Faculty of Medicine, Ankara, 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