{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:08:52Z","timestamp":1790730532598,"version":"4.1.0"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To assess anterior chamber configuration changes during phacoemulsification in primary angle-closure suspect (PACS\/PAC) and primary open-angle glaucoma (POAG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Prospective observational comparative study of anterior segment optical coherence tomography (AS-OCT) findings before and after phacoemulsification on three groups of patients (PACS\/PAC, POAG, and controls). Data were collected over a period of 9 months. Main outcome measures included mean change in anterior chamber depth (ACD), angle opening distance (AOD), and trabecular iris space area (TISA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      153 patients (51 PACS\/PAC, 51 POAG, and 51 controls) were included in the study. Change in all parameters (ACD, AOD at 500 um, and AOD at 750 um) between the groups demonstrated a greater change in PACS\/PAC as compared to POAG and controls. AOD at 750 \u03bcm in the temporal quadrant, which has been considered to be having the highest correlation or best representation of the angle, increased in all groups after phacoemulsification (463.59 \u00b1 10.99 vs. 656.27 \u00b1 9.73 mm in PACS; 521.29 \u00b1 16.36 vs. 674.37 \u00b1 8.72 mm in POAG; 549.27 \u00b1 12.40 vs. 702.82 \u00b1 13.04 mm in controls, (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). After phacoemulsification, intraocular pressure (IOP) decreased by 2.75 \u00b1 1.17 mm Hg in PACS\/PAC (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), 2.14 \u00b1 1.33 mm Hg in POAG and 1.90 \u00b1 1.25 mm Hg in controls and it was statistically significant in the PACS group compared to control (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                    <jats:p>\n                      <jats:bold>Conclusion<\/jats:bold>\n                      : Phacoemulsification with intraocular lens implantation is associated with increase in the ACD and angle parameters and a corresponding decrease in IOP. Findings were more pronounced in PACS\/PAC suggesting early phacoemulsification may be a treatment option in this group.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1538_21","type":"journal-article","created":{"date-parts":[[2022,2,16]],"date-time":"2022-02-16T07:51:02Z","timestamp":1644997862000},"page":"574-579","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":13,"title":["Lowering of intraocular pressure after phacoemulsification in primary open-angle and angle-closure glaucoma: Correlation with lens thickness"],"prefix":"10.4103","volume":"70","author":[{"given":"Mohideen Abdul","family":"Kader","sequence":"first","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital, Tirunelveli, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arkaprava","family":"Pradhan","sequence":"additional","affiliation":[{"name":"Department of Vitreo Retina, Sankara Nethralaya, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aakriti Garg","family":"Shukla","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Wills Eye Hospital, Philadelphia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devendra","family":"Maheswari","sequence":"additional","affiliation":[{"name":"Department of Vitreo Retina, Sankara Nethralaya, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Ramakrishnan","sequence":"additional","affiliation":[{"name":"Department of Vitreo Retina, Sankara Nethralaya, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debahuti","family":"Midya","sequence":"additional","affiliation":[{"name":"Department of Paediatric Ophthalmology, Sankara Nethralaya, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,1,27]]},"reference":[{"key":"R1-20251006","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1001\/archopht.1996.01100140435011","article-title":"Glaucoma in Mongolia. 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