{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:24:03Z","timestamp":1787772243060,"version":"build-2784847793"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To study the choroidal thickness (CT) and central macular thickness (CMT) in post-fever retinitis (PFR) and their correlation with visual acuity and treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      A retrospective, observational study of patients presenting with PFR from 2013 to 2021 and with spectral domain optical coherence tomography (SD-OCT) (Heidelberg\u00ae, Spectralis\n                      <jats:sup>TM<\/jats:sup>\n                      , Heidelberg, Germany) images were included. The CT and CMT were measured at presentation and at the final visit. The CT was measured subfoveally and at points 2000 \u00b5m superior, inferior, medial, and lateral from the fovea using the caliper tool.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Seventy-nine eyes of 65 patients were included for this study. The mean age was 39.03 (\u00b116.00) years with female preponderance of 53.84% (n = 35). Mean follow-up duration was 30 days. Mean CT at presentation and at follow-up was 254.12 \u00b5m and 241.51 \u00b5m, respectively. CT was decreased in majority of the eyes 67.1% (n = 53) from their baseline value. Mean CMTs at presentation and final visit were 454.8 \u00b5m and 223.7 \u00b5m, respectively. Best corrected visual acuity had a positive correlation with CMT (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      = 0.340;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.002) and negligible correlation with CT. A significant decrease in the mean CT was noted in patients who received doxycycline either alone or in combination with a steroid as compared to those who did not receive any treatment (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). The significance of which is unknown presently.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>CMT has a greater role in determining the final visual outcome than CT. CT can be reduced post-treatment with no effect on vision.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1557_23","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T04:00:31Z","timestamp":1713758431000},"page":"728-734","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Choroidal and central macular thickness before and after treatment in post fever retinitis"],"prefix":"10.4103","volume":"72","author":[{"given":"Srinivasan","family":"Sanjay","sequence":"first","affiliation":[{"name":"Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bengaluru, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isha","family":"Acharya","sequence":"additional","affiliation":[{"name":"Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bengaluru, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankush","family":"Kawali","sequence":"additional","affiliation":[{"name":"Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bengaluru, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sai Prashanti","family":"Chitturi","sequence":"additional","affiliation":[{"name":"Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bengaluru, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padmamalini","family":"Mahendradas","sequence":"additional","affiliation":[{"name":"Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bengaluru, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,4,22]]},"reference":[{"key":"R1-20260504","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.4103\/ijo.IJO_1352_20","article-title":"Post-fever retinitis-Newer concepts","volume":"68","author":"Mahendradas","year":"2020","journal-title":"Indian J Ophthalmol"},{"key":"R2-20260504","doi-asserted-by":"crossref","first-page":"91","DOI":"10.33590\/emjallergyimmunol\/20-00092","article-title":"Post fever uveoretinal manifestations in an immunocompetent individual","volume":"5","author":"Sanjay","year":"2020","journal-title":"EMJ Allergy Immunol"},{"key":"R3-20260504","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1038\/sj.eye.6702863","article-title":"Bilateral macular choroiditis following Chikungunya virus infection","volume":"21","author":"Chanana","year":"2007","journal-title":"Eye (Lond)"},{"key":"R4-20260504","doi-asserted-by":"crossref","first-page":"530","DOI":"10.5144\/0256-4947.2012.30.4.1105","article-title":"Dengue retinochoroiditis","volume":"32","author":"Tabbara","year":"2012","journal-title":"Ann Saudi Med"},{"key":"R5-20260504","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1080\/09273948.2019.1651872","article-title":"Multifocal choroiditis secondary to acute Zika virus infection","volume":"28","author":"Jimenez","year":"2020","journal-title":"Ocul Immunol Inflamm"},{"key":"R6-20260504","first-page":"637","article-title":"Ocular changes in scrub typhus. 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