{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:00:55Z","timestamp":1787169655720,"version":"build-2736575974"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To analyze the ocular biometric parameters of eyes with acute primary angle closure (APAC) as compared to fellow eyes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A cross-sectional study was conducted on 27 patients presenting with recent onset APAC to a tertiary eye institute in India. Anterior and posterior ocular biometric parameters were measured simultaneously by anterior segment optical coherence tomography (AS-OCT), A-scan, ultrasound biomicroscopy (UBM), and B-mode ultrasonogram (USG). The parameters measured were anterior chamber depth (ACD), anterior chamber angle (ACA), angle opening distance (AOD500, AOD750), lens vault (LV), axial length (AL), ciliary body thickness maximum (CBTmax) and at the point of scleral spur (CBT0), anterior placement of the ciliary body (APCB), and retinochoroidal thickness (RCS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Mean age \u00b1 SD of patients with APAC was 55.66 \u00b1 7.2 years with female preponderance (21:6 patients). Mean presenting IOP \u00b1 SD of the affected eye and fellow eye were 54.74 \u00b1 11.67 mm Hg and 18.7 \u00b1 11.67 mm Hg, respectively. Eyes with APAC had statistically significant narrower anterior ocular biometric parameters, higher LV, decreased ciliary body thickness, more APCB, and longer AL than the fellow eyes. CBTmax is the only variable that had significance (b = \u22120.421,95% CI: \u22120.806 to \u2212 0.035,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.034) in the univariate analysis with RCS thickness in APAC eyes. Further, there was a correlation between CBT0 and APCB with CBTmax both in univariate (b = 0.894,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.0001 and b = \u22120.351,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.039) and multivariable analysis (b = 0.911,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.0001 and b = \u22120.416,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.016)\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Compared to the fellow eyes, APAC eyes had different ocular biometric parameters. In addition to known biometric parameters associated with pupillary block (narrower anterior biometric parameters-ACA, ACD, and AOD), our study found multiple nonpupillary block factors such as higher lens vault and thinner and more anteriorly placed ciliary body to be associated with APAC.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1561_21","type":"journal-article","created":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T07:53:23Z","timestamp":1648454003000},"page":"1232-1238","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of uveal parameters between acute primary angle-closure eyes and fellow eyes in South Indian population"],"prefix":"10.4103","volume":"70","author":[{"given":"Vijayalakshmi A","family":"Senthilkumar","sequence":"first","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and Postgraduate Institute of Ohthalmology, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chinmayee","family":"Pradhan","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and Postgraduate Institute of Ohthalmology, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharmila","family":"Rajendrababu","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and Postgraduate Institute of Ohthalmology, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Krishnadas","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and Postgraduate Institute of Ohthalmology, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iswarya","family":"Mani","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Aravind Eye Hospital and Postgraduate Institute of Ohthalmology, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley","year":"2006","journal-title":"Br J Ophthalmol"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1136\/bjo.85.11.1277","article-title":"Glaucoma in China: How big is the problem?","volume":"85","author":"Foster","year":"2001","journal-title":"Br J Ophthalmol"},{"key":"B3-20240828","doi-asserted-by":"crossref","first-page":"S76","DOI":"10.4103\/0301-4738.73687","article-title":"An Indian perspective on primary angle closure and glaucoma","volume":"59","author":"Sihota","year":"2011","journal-title":"Indian J Ophthalmol"},{"key":"B4-20240828","first-page":"25","article-title":"Profile of glaucoma in a major eye hospital in north India","volume":"49","author":"Das","year":"2001","journal-title":"Indian J Ophthalmol"},{"key":"B5-20240828","first-page":"25","article-title":"Profile of the subtypes of angle closure glaucoma in a tertiary hospital in north India","volume":"46","author":"Sihota","year":"1998","journal-title":"Indian J Ophthalmol"},{"key":"B6-20240828","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.ophtha.2010.07.025","article-title":"Lens vault, thickness, and position in Chinese subjects with angle closure","volume":"118","author":"Nongpiur","year":"2011","journal-title":"Ophthalmology"},{"key":"B7-20240828","doi-asserted-by":"crossref","first-page":"3538","DOI":"10.1167\/iovs.13-11728","article-title":"Does acute primary angle-closure cause an increased choroidal thickness?","volume":"54","author":"Wang","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"B8-20240828","doi-asserted-by":"crossref","first-page":"e514","DOI":"10.1111\/aos.12403","article-title":"Is increased choroidal thickness association with primary angle closure?","volume":"92","author":"Zhou","year":"2014","journal-title":"Acta Ophthalmol"},{"key":"B9-20240828","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1136\/bjo.46.11.641","article-title":"Acute angle-closure glaucoma: The second eye: An analysis of 200 cases","volume":"46","author":"Lowe","year":"1962","journal-title":"Br J Ophthalmol"},{"key":"B10-20240828","doi-asserted-by":"crossref","first-page":"3299","DOI":"10.1167\/iovs.16-19558","article-title":"Quantitative measurements of the ciliary body in eyes with acute primary-angle closure","volume":"57","author":"Wang","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"B11-20240828","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1038\/s41433-018-0056-9","article-title":"Difference of uveal parameters between the acute primary angle closure eyes and the fellow eyes","volume":"32","author":"Li","year":"2018","journal-title":"Eye (Lond)"},{"key":"B12-20240828","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.ophtha.2006.05.073","article-title":"Detection of primary angle closure using anterior segment optical coherence tomography in Asian eyes","volume":"114","author":"Nolan","year":"2007","journal-title":"Ophthalmology"},{"key":"B13-20240828","doi-asserted-by":"crossref","first-page":"159","DOI":"10.4103\/0301-4738.27065","article-title":"Evaluation of the anterior chamber angle in Asian Indian eyes by ultrasound biomicroscopy and gonioscopy","volume":"54","author":"Kaushik","year":"2006","journal-title":"Indian J Ophthalmol"},{"key":"B14-20240828","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1159\/000510924","article-title":"Automatic classification of anterior chamber angle based on ultrasound biomicroscopy images","volume":"64","author":"Yu","year":"2021","journal-title":"Ophthalmic Res"},{"key":"B15-20240828","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1136\/bjo.86.2.238","article-title":"The definition and classification of glaucoma in prevalence surveys","volume":"86","author":"Foster","year":"2002","journal-title":"Br J Ophthalmol"},{"key":"B16-20240828","doi-asserted-by":"crossref","first-page":"3646","DOI":"10.1167\/iovs.13-13009","article-title":"Comparison of anterior segment parameters between the acute primary angle closure eye and the fellow eye","volume":"55","author":"Lee","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"B17-20240828","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1001\/archopht.123.4.527","article-title":"Anterior chamber depth and the risk of primary angle closure in 2 East Asian populations","volume":"123","author":"Aung","year":"2005","journal-title":"Arch Ophthalmol"},{"key":"B18-20240828","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1167\/iovs.09-4145","article-title":"Qualitative assessment of ultrasound biomicroscopic images using standard photographs: The Liwan eye study","volume":"51","author":"Jiang","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"B19-20240828","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1097\/IJG.0b013e318285fede","article-title":"Qualitative evaluation of the iris and ciliary body by ultrasound biomicroscopy in subjects with angle closure","volume":"23","author":"Ku","year":"2014","journal-title":"J Glaucoma"},{"key":"B20-20240828","first-page":"485","article-title":"Comparison of ciliary body anatomy between American Caucasians and Ethnic Chinese using ultrasound biomicroscopy","volume":"41","author":"He","year":"2016","journal-title":"Curr Eye Res"},{"key":"B21-20240828","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1159\/000107498","article-title":"Ocular biometry in acute and chronic angle-closure glaucoma","volume":"221","author":"Lan","year":"2007","journal-title":"Ophthalmologica"},{"key":"B22-20240828","article-title":"Ocular biometric characteristics of Chinese with history of acute angle closure","author":"Niu","year":"2018","journal-title":"J Ophthalmol 2018"},{"key":"B23-20240828","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1038\/sj.eye.6702709","article-title":"Effects of change in intraocular pressure on axial eye length and lens position","volume":"22","author":"Leydolt","year":"2008","journal-title":"Eye (Lond)"},{"key":"B24-20240828","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1007\/s10384-012-0173-0","article-title":"Changes in choroidal thickness and optical axial length accompanying intraocular pressure increase","volume":"56","author":"Hata","year":"2012","journal-title":"Jpn J Ophthalmol"},{"key":"B25-20240828","first-page":"526","article-title":"Choroidal thickness decreased in acute primary angle closure attacks with elevated intraocular pressure","volume":"41","author":"Song","year":"2016","journal-title":"Curr Eye Res"},{"key":"B26-20240828","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1001\/archophthalmol.2008.514","article-title":"Confirmation of the presence of uveal effusion in Asian eyes with primary angle closure glaucoma: An ultrasound biomicroscopy study","volume":"126","author":"Kumar","year":"2008","journal-title":"Arch Ophthalmol"},{"key":"B27-20240828","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1167\/iovs.11-8782","article-title":"Diurnal variation of choroidal thickness in normal, healthy subjects measured by spectral domain optical coherence tomography","volume":"53","author":"Tan","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"B28-20240828","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1167\/iovs.11-8383","article-title":"Circadian changes in subfoveal choroidal thickness and the relationship with circulatory factors in healthy subjects","volume":"53","author":"Usui","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_1561_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:10:42Z","timestamp":1787166642000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_1561_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,22]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_1561_21","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,22]]},"assertion":[{"value":"2021-06-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}