{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T01:34:58Z","timestamp":1790040898897,"version":"4.0.1"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To study the safety and efficacy of pre-operative suprachoroidal triamcinolone acetonide (SCTA) for achieving reduction\/resolution of serous choroidal detachment (CD) associated with rhegmatogenous retinal detachment (RRD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was a prospective, noncomparative, interventional pilot study. All consecutive patients presenting with RD and coexisting CD underwent transconjunctival injection of SCTA before proceeding with vitrectomy\/scleral buckle surgery. Sequential ultrasound B scans were performed for assessing the change in height of the CD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The mean age of the cohort was 53.8 \u00b1 10.8 years (range: 39\u201372 years). The CD was present in a median of 3 quadrants; the cumulative mean CD height was 5.59 mm (range: 2.02\u20139.42 mm). Following SCTA, a successful response (&gt;50% reduction) was seen in five eyes by day 3 and in two eyes by day 5. Three eyes failed to respond to SCTA and required surgical drainage before proceeding with vitrectomy. No intraprocedural injection-related complications were noted. A transient rise in the intraocular pressure (30 mmHg) was seen in one eye following vitrectomy and was managed successfully with topical antiglaucoma medications<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Suprachoroidal administration of triamcinolone appears to be a safe and effective technique to achieve CD resolution in eyes with RRD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1788_21","type":"journal-article","created":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T07:53:23Z","timestamp":1648454003000},"page":"1302-1306","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Safety and efficacy of suprachoroidal triamcinolone acetonide for the management of serous choroidal detachment prior to rhegmatogenous retinal detachment surgery: A Pilot study"],"prefix":"10.4103","volume":"70","author":[{"given":"Gaurav Mohan","family":"Kohli","sequence":"first","affiliation":[{"name":"Department of Vitreo-retina and Uveitis, Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India"},{"name":"Department of Ophthalmology, Hind Institute of Medical Sciences, Sitapur, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratik","family":"Shenoy","sequence":"additional","affiliation":[{"name":"Department of Vitreo-retina and Uveitis, Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danish","family":"Halim","sequence":"additional","affiliation":[{"name":"Department of Vitreo-retina and Uveitis, Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saurabh","family":"Nigam","sequence":"additional","affiliation":[{"name":"Department of Vitreo-retina and Uveitis, Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachin","family":"Shetty","sequence":"additional","affiliation":[{"name":"Department of Vitreo-retina and Uveitis, Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinesh","family":"Talwar","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Indraprastha Apollo Hospital and Center for Sight, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alok","family":"Sen","sequence":"additional","affiliation":[{"name":"Department of Vitreo-retina and Uveitis, Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/s12886-016-0319-9","article-title":"Risk factors for choroidal detachment following rhegmatogenous retinal detachment in a Chinese population","volume":"16","author":"Yu","year":"2016","journal-title":"BMC Ophthalmol"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1001\/archopht.1972.01000030483003","article-title":"Combined choroidal and retinal detachment","volume":"88","author":"Gottlieb","year":"1972","journal-title":"Arch Ophthalmol"},{"key":"B3-20240828","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1016\/S0161-6420(98)91230-1","article-title":"Primary vitrectomy for rhegmatogenous retinal detachment associated with choroidal detachment","volume":"105","author":"Sharma","year":"1998","journal-title":"Ophthalmology"},{"key":"B4-20240828","first-page":"664","article-title":"Rhegmatogenous retinal detachment complicated by severe intraocular inflammation, hypotony, and choroidal detachment","volume":"79","author":"Jarrett","year":"1981","journal-title":"Trans Am Ophthalmol Soc"},{"key":"B5-20240828","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.ophtha.2004.07.017","article-title":"Intravitreal triamcinolone-induced elevated intraocular pressure is associated with the development of posterior subcapsular cataracts","volume":"112","author":"Gillies","year":"2005","journal-title":"Ophthalmology"},{"key":"B6-20240828","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.addr.2018.03.001","article-title":"The suprachoroidal space as a route of administration to the posterior segment of the eye","volume":"126","author":"Chiang","year":"2018","journal-title":"Adv Drug Deliv Rev"},{"key":"B7-20240828","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1167\/tvst.5.6.14","article-title":"Suprachoroidal corticosteroid administration: A Novel route for local treatment of noninfectious uveitis","volume":"5","author":"Goldstein","year":"2016","journal-title":"Transl Vis Sci Technol"},{"key":"B8-20240828","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/IIO.0000000000000251","article-title":"Medical and surgical applications for the suprachoroidal space","volume":"59","author":"Emami-Naeini","year":"2019","journal-title":"Int Ophthalmol Clin"},{"key":"B9-20240828","doi-asserted-by":"crossref","first-page":"4749","DOI":"10.1167\/iovs.10-6291","article-title":"Pharmacokinetics of pars plana intravitreal injections versus microcannula suprachoroidal injections of bevacizumab in a porcine model","volume":"52","author":"Olsen","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"B10-20240828","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.ajo.2006.05.045","article-title":"Cannulation of the suprachoroidal space: A novel drug delivery methodology to the posterior segment","volume":"142","author":"Olsen","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"B11-20240828","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1001\/archopht.1974.03900060264003","article-title":"Choroidal detachment associated with primary retinal detachment","volume":"91","author":"Seelenfreund","year":"1974","journal-title":"Arch Ophthalmol"},{"key":"B12-20240828","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0002-9394(14)76695-4","article-title":"An updated classification of retinal detachment with proliferative vitreoretinopathy","volume":"112","author":"Machemer","year":"1991","journal-title":"Am J Ophthalmol"},{"key":"B13-20240828","first-page":"143","article-title":"Choroidal detachment in association with retinal detachment","volume":"32","author":"Azad","year":"1984","journal-title":"Indian J Ophthalmol"},{"key":"B14-20240828","first-page":"217","article-title":"Management of postoperative choroidal detachment","volume":"33","author":"Krishnan","journal-title":"Indian J Ophthalmol 1985"},{"key":"B15-20240828","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1038\/eye.2017.262","article-title":"Surgical outcomes of preoperative steroid for rhegmatogenous retinal detachment with associated choroidal detachment","volume":"32","author":"Denwattana","year":"2018","journal-title":"Eye (Lond)"},{"key":"B16-20240828","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1111\/aos.12694","article-title":"Perioperative pharmacological management of choroidal detachment associated with rhegmatogenous retinal detachment","volume":"94","author":"Shen","year":"2016","journal-title":"Acta Ophthalmol"},{"key":"B17-20240828","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jconrel.2015.02.021","article-title":"Safety and pharmacodynamics of suprachoroidal injection of triamcinolone acetonide as a controlled ocular drug release model","volume":"203","author":"Chen","year":"2015","journal-title":"J Control Release"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_1788_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:09:59Z","timestamp":1787166599000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_1788_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,22]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_1788_21","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,22]]},"assertion":[{"value":"2021-07-12","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}