{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:28:36Z","timestamp":1786649316878,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T00:00:00Z","timestamp":1725926400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To report the long-term anatomical and functional results of lens-sparing vitrectomy (LSV) for stage 4 retinopathy of prematurity (ROP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Retrospective study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This is a study of 23 eyes of 16 patients with stage 4 ROP who underwent lens-sparing vitrectomy at a tertiary care center and had a minimum of 2 years of follow-up. The main outcome measures are the retinal status and visual outcome at the final follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>After a mean follow-up of 7.36 years, the lenses remained clear in 69.57%; anatomical success in terms of the attached retina was achieved in 19\/23 eyes (82.61%) and vision of \u22656\/24 was achieved in 8\/23 eyes (34.78%), whereas navigational vision (\u22651\/60) was achieved in 16\/23 (69.56%). The mean spherical equivalent was \u22128.50 + 6.39 diopters. High myopia (\u22657 dsph) was noted in 43.47% of patients. The severity of myopia was not related to previous lasers and was less severe in eyes with posterior pole residual folds compared to normalized fundus or eyes with macular drag but no fold. At the final follow-up, 3\/16 (18.75%) patients had bilateral blindness due to total retinal detachments and 11\/16 (68.75%) had recorded functional vision in one or both eyes, whereas two others could potentially be having vision but could not be evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The long-term results of lens-sparing vitrectomy for stage 4 ROP are favorable with a majority retaining clear lenses and attached retina and two-thirds having functional vision.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_179_24","type":"journal-article","created":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T03:01:15Z","timestamp":1726023675000},"page":"S132-S138","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Long-term follow-up after lens-sparing vitrectomy for complications of retinopathy of prematurity"],"prefix":"10.4103","volume":"73","author":[{"given":"Lingam","family":"Gopal","sequence":"first","affiliation":[{"name":"Department of Vitreo Retinal Services, Medical Research Foundation, Chennai, Tamil Nadu, India"},{"name":"Department of Ophthalmology, National University Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pramod","family":"Bhende","sequence":"additional","affiliation":[{"name":"Department of Vitreo Retinal Services, Medical Research Foundation, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chetan","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Vitreo Retinal Services, Medical Research Foundation, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parveen","family":"Sen","sequence":"additional","affiliation":[{"name":"Department of Vitreo Retinal Services, Medical Research Foundation, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarun","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Columbia University Irving Medical Centre, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debarati","family":"Dasgupta","sequence":"additional","affiliation":[{"name":"Department of Vitreo Retinal Services, Medical Research Foundation, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,9,10]]},"reference":[{"issue":"Suppl 1","key":"R1-20260424","first-page":"35","article-title":"Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010","volume":"74","author":"Blencowe","year":"2013","journal-title":"Pediatr Res"},{"key":"R2-20260424","first-page":"1261","article-title":"National, regional, and global estimates of preterm birth in 2020, with trends from 2010: A systematic analysis","volume":"402","author":"Ohuma","year":"2023","journal-title":"Lancet"},{"key":"R2-20260424","first-page":"618","article-title":"Erratum","volume":"403","year":"2024","journal-title":"Lancet"},{"issue":"Suppl 1","key":"R3-20260424","first-page":"S103","article-title":"Retinopathy of prematurity: Overview and highlights of an initiative to integrate prevention, screening, and management into the public health system in India","volume":"68","author":"Gilbert","year":"2020","journal-title":"Indian J Ophthalmol"},{"key":"R4-20260424","first-page":"22064","article-title":"Cataract progression following lens-sparing pars plana vitrectomy for rhegmatogenous retinal detachment","volume":"12","author":"Bellucci","year":"2022","journal-title":"Sci Rep"},{"key":"R5-20260424","first-page":"20","article-title":"Lens clarity after 3 port lens sparing vitrectomy in stage 4A and 4B retinal detachments secondary to retinopathy of prematurity","volume":"124","author":"Lakhanpal","year":"2006","journal-title":"Arch Ophthalmol"},{"key":"R6-20260424","first-page":"302","article-title":"Vitrectomy surgery increases oxygen exposure to the lens: A possible mechanism for nuclear cataract formation","volume":"139","author":"Holekamp","year":"2005","journal-title":"Am J Ophthalmol"},{"key":"R7-20260424","first-page":"421","article-title":"Cataract formation following pars plana vitrectomy in the pediatric population","volume":"60","author":"Fernandez","year":"2023","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"R8-20260424","first-page":"835","article-title":"Refractive and ocular biometric profile of children with a history of laser treatment for retinopathy of prematurity","volume":"65","author":"Kaur","year":"2017","journal-title":"Indian J Ophthalmol"},{"key":"R9-20260424","first-page":"300","article-title":"Refractive outcomes of three-port lens sparing vitrectomy for retinopathy of prematurity (an AOS thesis)","volume":"107","author":"Holz","year":"2009","journal-title":"Trans Am Ophthalmol Soc"},{"key":"R10-20260424","first-page":"841","article-title":"Influence of laser versus lens-sparing vitrectomy on myopia in children with retinopathy of prematurity","volume":"65","author":"Agarkar","year":"2017","journal-title":"Indian J Ophthalmol"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_179_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:52:23Z","timestamp":1786647143000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_179_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,10]]},"references-count":11,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_179_24","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,10]]},"assertion":[{"value":"2024-01-17","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-30","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}