{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:36:55Z","timestamp":1786649815009,"version":"build-2736575974"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>The purpose of this study was to compare surgical outcomes and safety profiles of gonioscopy-assisted transluminal trabeculotomy (GATT) versus combined trabeculectomy and trabeculotomy (CTT) in primary congenital glaucoma (PCG) at 12 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Retrospective comparative analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      Children with mild-to-moderate PCG who underwent either GATT or CTT between December 2021 and June 2023 were included. Patients\u2019 data recorded at baseline and at postoperative periods of 1\n                      <jats:sup>st<\/jats:sup>\n                      , 3\n                      <jats:sup>rd<\/jats:sup>\n                      , 6\n                      <jats:sup>th<\/jats:sup>\n                      , and 12\n                      <jats:sup>th<\/jats:sup>\n                      months were analyzed. Intraocular pressure (IOP) reduction, incidence of complications, and the need for repeat examinations under anesthesia (EUA) were analyzed. Surgical success was defined as absolute when IOP \u226418 (criterion A) and \u226415 mmHg (criterion B) was achieved without medications and qualified, when achieved with medications. Failure was defined as IOP &gt;18 mmHg on maximal medical therapy, IOP &lt;6 mmHg, or the need for additional IOP-lowering surgery. Multivariate regression analysis was used to assess baseline predictors for binary outcomes (surgical success and any complication).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Ninety-eight eyes from 68 children diagnosed with PCG were analyzed, having undergone either CTT (58 eyes) or GATT (40 eyes) with 12-month follow-up, which showed similar success rates (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.6, Log Rank test). Multivariate analysis did not identify any significant baseline predictors of surgical success. Postoperative complications (34% vs 20%; adjusted\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.02) and need for repeat EUAs (0 vs 1.27\/eye;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.05) were significantly higher in the CTT group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In mild-moderate PCG eyes, GATT demonstrated similar surgical success with a better safety profile than CTT and can be preferred as the first-line surgical modality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1813_25","type":"journal-article","created":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T16:00:56Z","timestamp":1772035256000},"page":"451-457","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Comparing combined trabeculotomy\u2013trabeculectomy with gonioscopy-assisted transluminal trabeculotomy as primary surgery for primary congenital glaucoma"],"prefix":"10.4103","volume":"74","author":[{"given":"Anand K","family":"Pathak","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences (AIIMS), New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viney","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences (AIIMS), New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anurag","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences (AIIMS), New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shikha","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences (AIIMS), New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"key":"R1-20260417","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1097\/IJG.0000000000001259","article-title":"Prevalence and clinical characteristics of childhood glaucoma at a tertiary care children\u2019s hospital","volume":"28","author":"Bouhenni","year":"2019","journal-title":"J Glaucoma"},{"key":"R2-20260417","first-page":"76","article-title":"Epidemiology and genetics of primary congenital glaucoma in Slovakia. 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