{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T01:55:51Z","timestamp":1792029351142,"version":"4.4.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 3","license":[{"start":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T00:00:00Z","timestamp":1748563200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To study the early postoperative efficacy and safety of 5-0 prolene gonioscopy-assisted transluminal trabeculotomy (GATT) in juvenile open-angle glaucoma (JOAG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was a prospective, interventional study. Patients with JOAG planned for GATT were included. All patients were evaluated on postoperative days 1, 15, and 30 as well as 3 months and 6 months postoperatively. Baseline and follow-up visits were compared to determine the significant difference in intraocular pressure (IOP), number of antiglaucoma medications (AGMs), and best-corrected visual acuity. Other outcome measures included surgical success, complications, and interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Thirty eyes (28 patients) were included, of which 11 eyes had mild-to-moderate and 19 eyes had severe JOAG. Mean IOP reduced from preoperative 23.43 \u00b1 9.65 mmHg to 12.7 \u00b1 5.2 mmHg (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) at the end of 1 week and 14.52 \u00b1 7.3 mmHg, 13.83 \u00b1 6.29 mmHg, and 14.00 \u00b1 7.23 mmHg at the end of 1, 3, and 6 months, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). The mean number of AGM reduced from 2.93 \u00b1 0.87 to 0.5 at the end of 1 week and 0.69 \u00b1 1.17, 0.83 \u00b1 0.15, 0.80 \u00b1 0.96, and 0.80 \u00b1 0.96 at the end of 1, 3, and 6 months, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). The cumulative probability of overall success at the end of 6 months was 72.7% in the mild to moderate group and 73.7% in the advanced group (using both criteria 1 IOP \u22656 and \u226421 mmHg or a 20% reduction and criteria 2 IOP \u22656 and \u226418 mmHg or a 25% reduction). Hyphema was the most common complication. Macrohyphema (&gt;1 mm) was seen in one patient, out of which two patients required anterior chamber wash. IOP spikes (&gt;30 mmHg) were seen in two patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>GATT is efficacious and safe with good surgical outcomes in JOAG patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1864_24","type":"journal-article","created":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T05:00:17Z","timestamp":1748581217000},"page":"S449-S453","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Early outcomes of 5-0 prolene gonioscopy-assisted transluminal trabeculotomy in juvenile open-angle glaucoma"],"prefix":"10.4103","volume":"73","author":[{"given":"Devendra","family":"Maheshwari","sequence":"first","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivam","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhavi R","family":"Pillai","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nimrita","family":"Nagdev","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohideen A","family":"Kader","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rengappa","family":"Ramakrishnan","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,5,30]]},"reference":[{"key":"R1-20260422","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1080\/08820530701745199","article-title":"Clinical and genetic characteristics of primary juvenile-onset open-angle glaucoma (JOAG)","volume":"23","author":"Turalba","year":"2008","journal-title":"Semin Ophthalmol"},{"key":"R2-20260422","first-page":"243","article-title":"The distinction between juvenile and adult-onset primary open-angle glaucoma","volume":"58","author":"Wiggs","year":"1996","journal-title":"Am J Hum 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