{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:22:14Z","timestamp":1787775734990,"version":"build-2784847793"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To determine the proportion of people with type 2 diabetes mellitus (T2DM) attending large eye care facilities across India who have retinal vascular occlusion (RVO).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A 6-month descriptive, multicenter, observational hospital-based study of people was being presented to the 14 eye care facilities in India. The retina-specific component of comprehensive eye examination included stereoscopic biomicroscopy, binocular indirect ophthalmoscopy, and fundus fluorescein angiography, and optical coherence tomography was also available when needed. Data recording of the duration of diabetes, hypertension (HTN), stroke, and other variables was obtained from the medical history. The statistical analysis included frequencies, mean, and standard deviations for continuous variables. Odds ratio (OR) and multivariate analysis were undertaken to assess the associations between risk factors and RVO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The study recruited 11,182 consecutive patients (22,364 eyes) with T2DM. About 59.0% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 6697) were male. The mean age was 58.2 \u00b1 10.6 years. In this cohort, RVO was detected in 3.4% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 380) of patients; 67.6% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 257) of them had branch retinal vein occlusion (BRVO) and the remaining 32.4% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 123) had central retinal vein occlusion (CRVO). The frequency of unilateral BRVO (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 220, 85.6%) and unilateral CRVO (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 106, 86.18%) was much common. Unilateral RVO was more frequent (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 326, 85.8%) than bilateral diseases (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 54, 14.2%) (\u03c7\n                      <jats:sup>2<\/jats:sup>\n                      = 126.95,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). Ischemic CRVO was more common (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 103, 73.6%) than nonischemic CRVO (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 37, 26.4%). Macula-involving BRVO was found in 58.5% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 172) of cases, suggesting more than 50% of cases in RVO carries a risk of severe vision loss. The duration of diabetes apparently had no influence on the occurrence of RVO. On the multivariate analysis, a history of HTN [OR: 1.7; 95% confidence interval (CI): 1.3\u20132.1;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001) and stroke (OR: 5.1; 95% CI: 2.1\u201312.4;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) was associated with RVO.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>RVO is a frequent finding in people with T2DM. History of stroke carries the highest risk followed by HTN. The management of people with T2DM and RVO must also include comanagement of all associated systemic conditions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1934_19","type":"journal-article","created":{"date-parts":[[2020,1,16]],"date-time":"2020-01-16T05:03:16Z","timestamp":1579150996000},"page":"S27-S31","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Spectrum of Eye Disease in Diabetes (SPEED) in India: A prospective facility-based study. Report # 3. 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