{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T19:10:11Z","timestamp":1793214611607,"version":"4.5.0"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the role of swept-source optical coherence tomography (SS-OCT) in the management of acute Vogt\u2013Koyanagi\u2013Harada\u2019s (VKH) disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospective analysis of SS-OCT images of acute VKH patients between January 2015 and February 2020 in a tertiary eye care hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We studied 34 eyes of 17 patients with acute probable VKH disease. The mean age was 31.6 \u00b1 10.4 years. Twelve patients were women. The mean follow-up was 17.1 \u00b1 9.3 months. The mean visual acuity was 0.86 logMAR (Snellen equivalent: 6\/45) at presentation and 0.18 logMAR (Snellen equivalent: 6\/9) at the last follow-up. The mean subfoveal choroidal thickness (SFCT) was 784.97 microns at presentation, 431.40 microns at the first month of therapy, 453.94 microns at six months of therapy, and 405.83 microns at the last follow-up. Qualitative features noted on SS-OCT on presentation was subretinal fluid (SRF) in 29 (85%) eyes, subretinal hyperreflective dots in 34 (100%) eyes, subretinal septa in 33 (97%) eyes, RPE undulations in 21 (61.7%) eyes, posterior vitreous cells in 34 (100%) eyes, SRF around disc in 9 (26%) eyes, and disc swelling in 34 (100%) eyes. At the end of 1 year of follow-up, RPE undulations were absent in 30 eyes (88%) and disc swelling was notably absent in all 34 eyes (100%), though SRF around disc was noted in 4 eyes (11.7%) of 2 patients who had recurrences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>SFCT, SRF around disc, RPE undulation, and disc swelling may be important indicators on SS-OCT to guide therapy and prognosticate recurrences in acute VKH.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1944_21","type":"journal-article","created":{"date-parts":[[2022,7,12]],"date-time":"2022-07-12T06:28:32Z","timestamp":1657607312000},"page":"2458-2463","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["Role of Swept source optical coherence tomography in management of acute Vogt-Koyanagi-Harada\u2019s disease"],"prefix":"10.4103","volume":"70","author":[{"given":"Sudha K","family":"Ganesh","sequence":"first","affiliation":[{"name":"Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saurabh","family":"Mistry","sequence":"additional","affiliation":[{"name":"Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nivedita","family":"Nair","sequence":"additional","affiliation":[{"name":"Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,6,30]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.ajo.2005.01.046","article-title":"Comparative study of two sets of criteria for the diagnosis of Vogt-Koyanagi-Harada's disease [published correction appears in Am J Ophthalmol 2006 141 1179]","volume":"139","author":"Kitamura","year":"2005","journal-title":"Am J Ophthalmol"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"528","DOI":"10.3109\/09273948.2016.1151896","article-title":"Comparison of enhanced depth imaging and swept source optical coherence tomography in assessment of choroidal thickness in Vogt-Koyanagi-Harada disease","volume":"25","author":"Chee","year":"2017","journal-title":"Ocul Immunol Inflamm"},{"key":"B3-20240828","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1097\/IAE.0000000000001076","article-title":"Features of optical coherence tomography for the diagnosis of vogt-koyanagi-harada disease","volume":"36","author":"Liu","year":"2016","journal-title":"Retina"},{"key":"B4-20240828","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1097\/IAE.0b013e3182083beb","article-title":"Choroidal evaluation using enhanced depth imaging spectral-domain optical coherence tomography in Vogt-Koyanagi-Harada disease","volume":"31","author":"Fong","year":"2011","journal-title":"Retina"},{"key":"B5-20240828","doi-asserted-by":"crossref","first-page":"e490","DOI":"10.1111\/aos.12384","article-title":"Choroidal thickness in eyes with posterior recurrence of Vogt-Koyanagi-Harada disease after high-dose steroid therapy","volume":"92","author":"Hashizume","year":"2014","journal-title":"Acta Ophthalmol"},{"key":"B6-20240828","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/S0002-9394(01)00925-4","article-title":"Revised diagnostic criteria for Vogt-Koyanagi-Harada disease:Report of an international committee on nomenclature","volume":"131","author":"Read","year":"2001","journal-title":"Am J Ophthalmol"},{"key":"B7-20240828","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1097\/IAE.0b013e3181eef053","article-title":"Subfoveal choroidal thickness after treatment of Vogt-Koyanagi-Harada disease","volume":"31","author":"Maruko","year":"2011","journal-title":"Retina"},{"key":"B8-20240828","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1097\/IAE.0b013e31826710ea","article-title":"Intravitreal cellular infiltrate imaged as punctate spots by spectral-domain optical coherence tomography in eyes with posterior segment inflammatory disease","volume":"33","author":"Saito","year":"2013","journal-title":"Retina"},{"key":"B9-20240828","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.ajo.2005.03.057","article-title":"Standardization of uveitis nomenclature for reporting clinical data. 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