{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:36:50Z","timestamp":1786649810961,"version":"build-2736575974"},"reference-count":37,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,3]]},"abstract":"\n Purpose:<\/jats:title>\n This study aimed to evaluate Schlemm\u2019s canal (SC) parameters using anterior segment optical coherence tomography (AS-OCT) in eyes undergoing Descemet membrane endothelial keratoplasty (DMEK).<\/jats:p>\n <\/jats:sec>\n \n Design:<\/jats:title>\n This is a retrospective, cross-sectional, observational study.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n The study included 22 eyes from 22 patients with pseudophakic bullous keratopathy, with a mean age of 70 \u00b1 11.4 years. AS-OCT (Triton) scans were performed with the patient fixating nasally; horizontal images were obtained from the temporal limbus to visualize SC.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n A significant difference was found in visual acuity [1.9 (0.5\u20132.3) LogMAR vs. 0.5 (0.1\u20132.3) LogMAR, respectively] and central corneal thickness (CCT) [850 (630\u2013950) \u00b5m vs. 545 (407\u2013900) \u00b5m, respectively] before and after DMEK surgery (\n P<\/jats:italic>\n < 0.01 for both). No significant difference was observed in postoperative intraocular pressure (IOP) [12 (6\u201320) mmHg] compared to preoperative values [13 (6\u201318) mmHg] (\n P<\/jats:italic>\n = 1.00). There was a significant difference between the preoperative and postoperative SC length (SCL) values (249 \u00b5m vs. 266.5 \u00b5m, respectively;\n P<\/jats:italic>\n < 0.001) as well as SC area (SCA) values (4893.5 \u00b5m\u00b2 vs. 5227 \u00b5m\u00b2, respectively) at the third month (\n P<\/jats:italic>\n = 0.001). Changes in CCT and IOP were not significantly correlated with changes in SCA (\n P<\/jats:italic>\n = 0.658 vs.\n P<\/jats:italic>\n = 0.460) or SCL (\n P<\/jats:italic>\n = 0.435 vs.\n P<\/jats:italic>\n = 0.377). Tamponade with sulfur hexafluoride (SF\u2086) or air did not significantly affect preoperative and postoperative SCA (\n P<\/jats:italic>\n = 0.974 vs.\n P<\/jats:italic>\n = 0.821, respectively) and SCL (\n P<\/jats:italic>\n = 0.974 vs.\n P<\/jats:italic>\n = 0.792, respectively).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n AS-OCT imaging revealed postoperative expansion of SC parameters following DMEK, with no detectable adverse impact attributable to the surgical procedure or SF\u2086 use.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1947_25","type":"journal-article","created":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T16:00:50Z","timestamp":1772035250000},"page":"438-443","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Anterior segment optical coherence tomography assessment of Schlemm\u2019s canal before and after Descemet membrane endothelial keratoplasty: A retrospective observational study"],"prefix":"10.4103","volume":"74","author":[{"given":"Fatma Isil","family":"Sozen-Delil","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burak","family":"Tanyildiz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erdi","family":"Karadag","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"key":"R1-20260417","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1097\/ICO.0000000000003310","article-title":"Comparison of long-term outcomes of DSEK and DMEK in 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