{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:36:30Z","timestamp":1786649790736,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>This study aimed to describe visual outcomes in cases of pediatric uveitis in an Indian population and to analyze various factors affecting these outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Single-center, retrospective chart review of 277 cases of uveitis in patients under the age of 18 years. Variables assessed included age and sex distribution, anatomical location of uveitis, systemic associations, complications, and various treatment strategies used, including long-term immunomodulation and surgical management of complications if required. The main outcome was the final visual acuity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      At the final visit, 51.5% of the eyes showed improvement in the final visual acuity, while vision remained stable in 28.7% and 19.7% of the eyes showed worsening of vision at the final follow-up. A total of 19.4% of patients were blind in at least one eye at the final visit, and 16 patients (5.77%) remained bilaterally blind at the final follow-up. The presence of cataract (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0), posterior uveitis (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.005), and retinal detachment (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.014) were the most significant risk factors for predicting worse visual outcomes. More than half (65.7%) of patients reported a complication at some point in their follow-up, and the most common complication was cataract. In total, 50.9% of patients required long-term immunomodulatory therapy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Pediatric uveitis remains a challenging condition to treat and follow-up, and the visual outcome remains guarded for most patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_1993_22","type":"journal-article","created":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T03:31:03Z","timestamp":1684294263000},"page":"2158-2161","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":12,"title":["Visual outcome in pediatric uveitis: A retrospective data review in 277 children"],"prefix":"10.4103","volume":"71","author":[{"given":"Prasanna","family":"Sivakoti","sequence":"first","affiliation":[{"name":"Resident, Sankara Nethralaya, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meenakshi","family":"Swaminathan","sequence":"additional","affiliation":[{"name":"Department of Strabismus and Pediatric Ophthalmology Medical and Vision Research Foundations, Sankara Nethralaya, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kowsigan","family":"Magesan","sequence":"additional","affiliation":[{"name":"Department of Optometry, Sankara Nethralaya, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richa","family":"Pyare","sequence":"additional","affiliation":[{"name":"Department of Uvea, Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amala E","family":"George","sequence":"additional","affiliation":[{"name":"Department of Uvea, Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudha K","family":"Ganesh","sequence":"additional","affiliation":[{"name":"Department of Uvea, Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyotirmay","family":"Biswas","sequence":"additional","affiliation":[{"name":"Department of Uvea, Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parthopratim","family":"Dutta Majumder","sequence":"additional","affiliation":[{"name":"Department of Uvea, Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,5,17]]},"reference":[{"key":"R1-20251006","doi-asserted-by":"crossref","first-page":"140","DOI":"10.4103\/0974-620X.122267","article-title":"Pediatric uveitis:An update","volume":"6","author":"Majumder","year":"2013","journal-title":"Oman J Ophthalmol"},{"key":"R2-20251006","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1076\/ocii.8.4.251.6459","article-title":"Uveitis in children","volume":"8","author":"Cunningham","year":"2000","journal-title":"Ocul Immunol Inflamm"},{"key":"R3-20251006","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1136\/bjo.87.7.879","article-title":"Visual loss in uveitis of childhood","volume":"87","author":"de","year":"2003","journal-title":"Br J Ophthalmol"},{"key":"R4-20251006","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/s12886-019-1139-5","article-title":"Patterns of uveitis in children according to 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Ophthalmol"},{"key":"R8-20251006","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1177\/112067210301300704","article-title":"Prognosis of juvenile rheumatoid arthritis-associated uveitis","volume":"13","author":"Paroli","year":"2003","journal-title":"Eur J Ophthalmol"},{"key":"R9-20251006","first-page":"25158414211027708","article-title":"Pediatric uveitis:A retrospective analysis at a tertiary eye care hospital in South India","volume":"13","author":"Raveendra","year":"2021","journal-title":"Ther Adv Ophthalmol"},{"key":"R10-20251006","doi-asserted-by":"crossref","first-page":"402","DOI":"10.3109\/09273948.2015.1012298","article-title":"Pattern of pediatric uveitis seen at a tertiary referral center from India","volume":"24","author":"Ganesh","year":"2016","journal-title":"Ocul Immunol Inflamm"},{"key":"R11-20251006","doi-asserted-by":"crossref","first-page":"199","DOI":"10.4103\/0301-4738.31940","article-title":"Analysis of juvenile idiopathic arthritis associated uveitis in India over the last 16 years","volume":"55","author":"Sudharshan","year":"2007","journal-title":"Indian J Ophthalmol"}],"container-title":["Indian Journal of 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