{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:35:03Z","timestamp":1786649703282,"version":"build-2736575974"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>Screening guidelines for retinopathy of prematurity (ROP) are updated frequently to help clinicians identify infants at risk of type 1 ROP. This study aims to evaluate the accuracy of three different predictive algorithms\u2014WINROP, ROPScore, and CO-ROP\u2014in detecting ROP in preterm infants in a developing country.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This retrospective study was conducted on 386 preterm infants from two centers between 2015 and 2021. Neonates with gestational age \u226430 weeks and\/or birth weight \u22641500 g who underwent ROP screening were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>One hundred twenty-three neonates (31.9%) developed ROP. The sensitivity to identify type 1 ROP was as follows: WINROP, 100%; ROPScore, 100%; and CO-ROP, 92.3%. The specificity was 28% for WINROP, 1.4% for ROPScore, and 19.3% for CO-ROP. CO-ROP missed two neonates with type 1 ROP. WINROP provided the best performance for type 1 ROP with an area under the curve score at 0.61.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The sensitivity was at 100% for WINROP and ROPScore for type 1 ROP; however, specificity was quite low for both algorithms. Highly specific algorithms tailored to our population may serve as a useful adjunctive tool to detect preterm infants at risk of sight-threatening ROP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2013_22","type":"journal-article","created":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T09:04:33Z","timestamp":1686733473000},"page":"2555-2560","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Validation of three weight gain-based algorithms as a screening tool to detect retinopathy of prematurity: A multicenter study"],"prefix":"10.4103","volume":"71","author":[{"given":"Lina","family":"Raffa","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, King Abdulaziz University, Jeddah, Saudi Arabia"},{"name":"Department of Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliaa","family":"Alamri","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, King Abdulaziz University Hospital, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal","family":"Alosaimi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Alessa","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, King Abdulaziz University, Jeddah, Saudi Arabia"},{"name":"Department of Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzan","family":"Alharbi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Jeddah Eye Hospital, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huda","family":"Ahmedhussain","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, King Abdulaziz University, Jeddah, Saudi Arabia"},{"name":"Department of Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hashem","family":"Almarzouki","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia"},{"name":"Department of Ophthalmology, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia"},{"name":"King Abdullah International Medical Research Center, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mansour","family":"AlQurashi","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia"},{"name":"King Abdullah International Medical Research Center, Jeddah, Saudi Arabia"},{"name":"Department of Pediatrics, Neonatology Division, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Western Region, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,6,14]]},"reference":[{"key":"R1-20251006","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.jaapos.2012.09.004","article-title":"An update on progress and the changing epidemiology of causes of childhood blindness worldwide","volume":"16","author":"Kong","year":"2012","journal-title":"J Am Assoc Pediatr Ophthalmol Strabismus"},{"key":"R2-20251006","first-page":"720","article-title":"Retinopathy of prematurity at a University Hospital in Riyadh, Saudi Arabia","volume":"24","author":"Al-Amro","year":"2003","journal-title":"Saudi Med J"},{"key":"R3-20251006","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1136\/bjo.2007.126508","article-title":"Retinopathy of prematurity in Saudi Arabia:Incidence, risk factors, and the applicability of current screening criteria","volume":"92","author":"Binkhathlan","year":"2008","journal-title":"Br J Ophthalmol"},{"key":"R4-20251006","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1136\/bjophthalmol-2012-301570","article-title":"Retinopathy of prematurity:Are we missing any infant with retinopathy of prematurity?","volume":"96","author":"Amer","year":"2012","journal-title":"Br J Ophthalmol"},{"key":"R5-20251006","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.sjopt.2016.02.006","article-title":"Incidence of retinopathy of prematurity at two tertiary centers in Jeddah, Saudi Arabia","volume":"30","author":"Waheeb","year":"2016","journal-title":"Saudi J Ophthalmol"},{"key":"R6-20251006","doi-asserted-by":"crossref","first-page":"235","DOI":"10.4103\/meajo.MEAJO_131_18","article-title":"Retinopathy of prematurity incidence and risk factors in a tertiary hospital in Riyadh, Saudi Arabia","volume":"26","author":"Al-Qahtani","year":"2019","journal-title":"Middle East Afr J Ophthalmol"},{"key":"R7-20251006","doi-asserted-by":"crossref","first-page":"87","DOI":"10.5144\/0256-4947.2020.87","article-title":"Screening premature infants for retinopathy of prematurity in a tertiary hospital in Saudi Arabia","volume":"40","author":"Mgharbil","year":"2020","journal-title":"Ann Saudi Med"},{"key":"R8-20251006","doi-asserted-by":"crossref","first-page":"31","DOI":"10.4103\/jcn.jcn_171_20","article-title":"Retinopathy of prematurity:Incidence and perinatal risk factors in a tertiary hospital in Saudi Arabia","volume":"10","author":"Ahmedhussain","year":"2021","journal-title":"J Clin Neonatol"},{"key":"R9-20251006","doi-asserted-by":"crossref","first-page":"359","DOI":"10.4103\/tjo.tjo_72_20","article-title":"Retinopathy of prematurity in Saudi Arabia:Exploring maternal risk factors","volume":"11","author":"Badeeb","year":"2021","journal-title":"Taiwan J Ophthalmol"},{"key":"R10-20251006"},{"key":"R11-20251006","doi-asserted-by":"crossref","first-page":"e20183061","DOI":"10.1542\/peds.2018-3061","article-title":"Screening examination of premature infants for retinopathy of prematurity","volume":"142","year":"2018","journal-title":"Pediatrics"},{"key":"R12-20251006","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1001\/archopht.121.12.1684","article-title":"Revised indications for the treatment of retinopathy of prematurity: Results of the early treatment for retinopathy of prematurity randomized trial","volume":"121","year":"2003","journal-title":"Arch Ophthalmol"},{"key":"R13-20251006","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/aos.13117","article-title":"Predictive algorithms for early detection of retinopathy of prematurity","volume":"95","author":"Piermarocchi","year":"2017","journal-title":"Acta Ophthalmol (Copenh)"},{"key":"R14-20251006","doi-asserted-by":"crossref","first-page":"e638","DOI":"10.1542\/peds.2008-2697","article-title":"Early weight gain predicts retinopathy in preterm infants:New, simple, efficient approach to screening","volume":"123","author":"Hellstr\u00f6m","year":"2009","journal-title":"Pediatrics"},{"key":"R15-20251006","first-page":"622","article-title":"Validation of a new retinopathy of prematurity screening method monitoring longitudinal postnatal weight and insulinlike growth factor I","volume":"127","author":"L\u00f6fqvist","year":"2009","journal-title":"Arch Ophthalmol Chic Ill 1960"},{"key":"R16-20251006","first-page":"443","article-title":"Longitudinal postnatal weight measurements for the prediction of retinopathy of prematurity","volume":"128","author":"Wu","year":"2010","journal-title":"Arch Ophthalmol Chic Ill 1960"},{"key":"R17-20251006","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jaapos.2015.10.017","article-title":"The Colorado-retinopathy of prematurity model (co-Rop):Postnatal weight gain screening algorithm","volume":"20","author":"Cao","year":"2016","journal-title":"J Am Assoc Pediatr Ophthalmol Strabismus"},{"key":"R18-20251006","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1001\/archophthalmol.2010.255","article-title":"Predicting proliferative retinopathy in a Brazilian population of preterm infants with the screening algorithm WINROP","volume":"128","author":"H\u00e5rd","year":"2010","journal-title":"Arch Ophthalmol"},{"key":"R19-20251006","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1001\/archophthalmol.2012.215","article-title":"Prediction of retinopathy of prematurity using the screening algorithm WINROP in a Mexican population of preterm infants","volume":"130","author":"Zepeda-Romero","year":"2012","journal-title":"Arch Ophthalmol"},{"key":"R20-20251006","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1159\/000351297","article-title":"The Use of the WINROP screening algorithm for the prediction of retinopathy of prematurity in a Chinese population","volume":"104","author":"Sun","year":"2013","journal-title":"Neonatology"},{"key":"R21-20251006","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1001\/jamaophthalmol.2013.566","article-title":"Efficacy of the screening algorithm WINROP in a Korean population of preterm infants","volume":"131","author":"Choi","year":"2013","journal-title":"JAMA Ophthalmol"},{"key":"R22-20251006","doi-asserted-by":"crossref","first-page":"110","DOI":"10.4103\/ijo.IJO_486_17","article-title":"WINROP algorithm for prediction of sight threatening retinopathy of prematurity:Initial experience in Indian preterm infants","volume":"66","author":"Sanghi","year":"2018","journal-title":"Indian J Ophthalmol"},{"key":"R23-20251006","doi-asserted-by":"crossref","first-page":"e377","DOI":"10.6061\/clinics\/2018\/e377","article-title":"The ROPScore as a screening algorithm for predicting retinopathy of prematurity in a Brazilian population","volume":"73","author":"Lucio","year":"2018","journal-title":"Clinics (Sao Paulo)"},{"key":"R24-20251006","doi-asserted-by":"crossref","first-page":"622","DOI":"10.15537\/smj.2020.6.25127","article-title":"Prediction of retinopathy of prematurity using the screening algorithm WINROP in a Saudi cohort of preterm infants","volume":"41","author":"Raffa","year":"2020","journal-title":"Saudi Med J"},{"key":"R25-20251006","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1001\/archopht.123.7.991","article-title":"The International Classification of Retinopathy of Prematurity Revisited","volume":"123","year":"2005","journal-title":"Arch Ophthalmol"},{"key":"R26-20251006","first-page":"233","article-title":"Final results of the early treatment for retinopathy of prematurity (ETROP) randomized trial","volume":"102","author":"Good","year":"2004","journal-title":"Trans Am Ophthalmol Soc"},{"key":"R27-20251006","article-title":"Applicability of the ROPScore as a predictive algorithm for early detection of retinopathy of prematurity","volume":"44","author":"Figueiredo","year":"2020","journal-title":"Rev Soc Port Oftalmol"},{"key":"R28-20251006","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1093\/biomet\/26.4.404","article-title":"The use of confidence or fiducial limits illustrated in the case of the binomial","volume":"26","author":"Clopper","year":"1934","journal-title":"Biometrika"},{"key":"R29-20251006","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1016\/S0140-6736(13)60178-6","article-title":"Retinopathy of prematurity","volume":"382","author":"Hellstr\u00f6m","year":"2013","journal-title":"Lancet"},{"key":"R30-20251006","doi-asserted-by":"crossref","first-page":"e2135879","DOI":"10.1001\/jamanetworkopen.2021.35879","article-title":"The use of postnatal weight gain algorithms to predict severe or type 1 retinopathy of prematurity:A systematic review and meta-analysis","volume":"4","author":"Athikarisamy","year":"2021","journal-title":"JAMA Netw Open"},{"key":"R31-20251006","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.jaapos.2016.08.008","article-title":"Prediction of severe retinopathy of prematurity using the screening algorithm WINROP in preterm infants","volume":"20","author":"Ko\u00e7ak","year":"2016","journal-title":"J AAPOS"},{"key":"R32-20251006","doi-asserted-by":"crossref","first-page":"476","DOI":"10.5935\/0004-2749.20190093","article-title":"Validation of ROPScore to predict retinopathy of prematurity among very low birth weight preterm infants in a southern Brazilian population","volume":"82","author":"Cagliari","year":"2019","journal-title":"Arq Bras Oftalmol"},{"key":"R33-20251006","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1007\/s13312-021-2321-4","article-title":"Diagnostic accuracy of WINROP, CHOP-ROP and ROPScore in detecting type 1 retinopathy of prematurity","volume":"58","author":"Thomas","year":"2021","journal-title":"Indian Pediatr"},{"key":"R34-20251006","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.jaapos.2017.03.009","article-title":"Colorado retinopathy of prematurity screening algorithm (CO-ROP):A validation study at a tertiary care center","volume":"21","author":"Huang","year":"2017","journal-title":"J AAPOS"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_2013_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:57:18Z","timestamp":1786647438000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_2013_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_2013_22","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"2022-08-14","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-13","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}