{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T07:37:32Z","timestamp":1793173052635,"version":"4.5.0"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To establish normative data on anterior scleral thickness using the spectral domain anterior segment optical coherence tomography (AS-OCT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In total, 200 eyes of 100 healthy subjects underwent AS-OCT scans in the temporal and nasal quadrants. The scleral + conjunctival complex thickness (SCT) was measured by a single examiner. Mean SCT was analyzed for differences across age groups, gender, and location (nasal versus temporal).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Mean age was 46.4 \u00b1 18.3 (21\u201384) years; male to female ratio was 54:46. Mean SCT (nasal + temporal) of the right eye (RE) was 682.3 \u00b1 64.2 \u03bcm in males and 660.6 \u00b1 57.1 \u03bcm in females. In the left eye (LE), it was 684.6 \u00b1 64.9 \u03bcm in males and 661.8 \u00b1 49.3 \u03bcm in females. These differences between male and female for both eyes were statistically significant (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.006 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.002). The mean SCT of temporal and nasal quadrants in the RE was 678.54 \u00b1 57.50 and 666 \u00b1 66.2 \u03bcm, respectively. In the LE, the temporal mean SCT quadrant was 679.6 \u00b1 55.8 \u03bcm, and the nasal was 668.6 \u00b1 63.6 \u03bcm. Age had a negative correlation with SCT (\u22120.62 \u03bcm\/year;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.03), and males had a higher temporal SCT than females (22 \u03bcm higher;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.03). After adjusting for age and gender in a multivariate analysis, temporal SCT was significantly (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) higher than nasal SCT.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In our study, mean SCT decreased with age and males had a higher temporal SCT. This is the first study to evaluate scleral thickness in the Indian population, and the data can be used as a baseline for comparing variations in scleral thickness in disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2046_22","type":"journal-article","created":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T03:37:44Z","timestamp":1684294664000},"page":"1833-1836","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":11,"title":["Scleral thickness in normal Indian eyes measured using spectral domain anterior segment optical coherence tomography"],"prefix":"10.4103","volume":"71","author":[{"given":"Hasna","family":"Kommula","sequence":"first","affiliation":[{"name":"Shantilal Shanghvi Cornea Institute, L V Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somasheila I","family":"Murthy","sequence":"additional","affiliation":[{"name":"Shantilal Shanghvi Cornea Institute, L V Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhinav","family":"Loomba","sequence":"additional","affiliation":[{"name":"Shantilal Shanghvi Cornea Institute, L V Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashik","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Ophthalmic Biophysics, L V Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashmi","family":"Ranjan","sequence":"additional","affiliation":[{"name":"Shantilal Shanghvi Cornea Institute, L V Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,5,17]]},"reference":[{"key":"R1-20251006","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0014-4835(03)00212-4","article-title":"Scleral structure, organisation and disease","volume":"78","author":"Watson","year":"2004","journal-title":"A review. 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