{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:35:15Z","timestamp":1786649715053,"version":"build-2736575974"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To report on the microbiological profile and antibiotic sensitivity patterns of infectious keratitis at a tertiary center in central India.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The suspected case of severe keratitis underwent microbiological culture and identification using the VITEK 2 technique. Antibiotic susceptibility for different sensitivity and resistance patterns was analyzed. Demographics, clinical profile, and socioeconomic history was also documented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Culture was positive in 233\/455 (51.2%) patients. Pure bacterial growth was present in 83 (35.62%) patients and pure fungus was present in 146 (62.66%) patients. The most common bacterial cause of infectious keratitis was\n                      <jats:italic toggle=\"yes\">Pseudomonas<\/jats:italic>\n                      followed by\n                      <jats:italic toggle=\"yes\">Staphylococcus<\/jats:italic>\n                      and\n                      <jats:italic toggle=\"yes\">Bacillus<\/jats:italic>\n                      .\n                      <jats:italic toggle=\"yes\">Pseudomonas<\/jats:italic>\n                      showed 65%\u201375% resistance against levofloxacin, ceftazidime, imipenem, gentamycin, ciprofloxacin, and amikacin.\n                      <jats:italic toggle=\"yes\">Staphylococcus<\/jats:italic>\n                      showed 65%\u201370% resistance against levofloxacin, erythromycin, and ciprofloxacin, with\n                      <jats:italic toggle=\"yes\">Streptococcus<\/jats:italic>\n                      being 100% resistant to erythromycin.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study highlights the current trend of microbiological profiles of infectious keratitis and their antibiotic susceptibility at a rural setup in central India. Fungal predominance and increased resistance against the commonly used antibiotics were noted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2070_22","type":"journal-article","created":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T09:06:22Z","timestamp":1686733582000},"page":"2455-2459","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":13,"title":["Microbial keratitis and antibiotic sensitivity patterns: A retrospective analysis at a tertiary center in Central India"],"prefix":"10.4103","volume":"71","author":[{"given":"Gautam Singh","family":"Parmar","sequence":"first","affiliation":[{"name":"Department of Cornea and Refractive Surgery, Sadguru Netra Chikitsalaya and Postgraduate Institute of Ophthalmology, Chitrakoot, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok Kumar","family":"Meena","sequence":"additional","affiliation":[{"name":"Department of 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